Detailed information    

insolico Bioinformatically predicted

Overview

Name   cinA   Type   Machinery gene
Locus tag   KPU57_RS12615 Genome accession   NZ_CP076471
Coordinates   2608468..2609709 (-) Length   413 a.a.
NCBI ID   WP_130587399.1    Uniprot ID   -
Organism   Enterococcus faecium strain UAMS_EF58     
Function   facilitate localization of RecA (predicted from homology)   
Homologous recombination

Genomic Context

Location: 2603468..2614709
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  KPU57_RS12600 (KPU57_12560) proC 2604458..2605264 (+) 807 WP_002296027.1 pyrroline-5-carboxylate reductase -
  KPU57_RS12605 (KPU57_12565) rny 2605343..2606899 (-) 1557 WP_002287336.1 ribonuclease Y -
  KPU57_RS12610 (KPU57_12570) recA 2607310..2608359 (-) 1050 WP_002287328.1 recombinase RecA Machinery gene
  KPU57_RS12615 (KPU57_12575) cinA 2608468..2609709 (-) 1242 WP_130587399.1 competence/damage-inducible protein A Machinery gene
  KPU57_RS12620 (KPU57_12580) pgsA 2609949..2610527 (-) 579 WP_002296025.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  KPU57_RS12625 (KPU57_12585) - 2610736..2611659 (-) 924 WP_002287423.1 RodZ domain-containing protein -
  KPU57_RS12630 (KPU57_12590) - 2612398..2613684 (-) 1287 WP_002287425.1 pitrilysin family protein -

Sequence

Protein


Download         Length: 413 a.a.        Molecular weight: 45433.80 Da        Isoelectric Point: 4.6507

>NTDB_id=575622 KPU57_RS12615 WP_130587399.1 2608468..2609709(-) (cinA) [Enterococcus faecium strain UAMS_EF58]
MKAEIIAVGTELLLGQVVNTNATFLSEQLADLGIEVYYQTVVGDNQQRLEELIALAETRSELILLCGGLGPTEDDLTKEA
TAAHLGKSLMQNTEGYKKLLAYFETTHRKMTKNNLQQSQIIEGGVPLPNRTGLALGTFYQTDTHAYILLPGPPNELKPMF
VEQVRPLLEERFPSEEKLISKVLRFYGIGESRLVTELKDLIETQINPTIAPYAKPNEVTLRLTVKTNDVQAGNQALLALE
EKIQERVGEYFYGYGDDNSLAKVVVELLKENKQTVTAAESLTAGAFQAALGDIAGVSEVFPGGFVTYSLQTKAGFLEIDP
ELLAEYGTVSKECVEQMAIQAREIARTDYSVAFTGVAGPDTLEGQSAGTVWIAISSKDGVVSEKYHFARDRAAIRYNAVM
QGFDLLRKQLLRK

Nucleotide


Download         Length: 1242 bp        

>NTDB_id=575622 KPU57_RS12615 WP_130587399.1 2608468..2609709(-) (cinA) [Enterococcus faecium strain UAMS_EF58]
ATGAAAGCAGAAATAATAGCTGTCGGAACAGAACTTTTACTAGGACAAGTCGTGAATACGAATGCCACTTTCTTGTCAGA
ACAGCTAGCTGATCTAGGTATCGAAGTTTATTATCAAACAGTTGTAGGAGATAATCAGCAGCGTTTAGAAGAGTTGATTG
CTCTAGCTGAAACAAGAAGTGAACTCATACTCTTATGTGGCGGATTAGGACCGACAGAAGATGACCTGACAAAAGAAGCA
ACTGCGGCTCACCTCGGTAAGTCTCTCATGCAAAATACGGAAGGATACAAAAAATTATTGGCATATTTTGAAACAACCCA
TCGAAAAATGACCAAAAACAATCTGCAACAGTCCCAGATTATCGAAGGCGGGGTTCCTCTACCAAATCGTACAGGGCTTG
CTTTAGGGACTTTTTATCAAACAGATACACATGCGTATATCCTTCTTCCCGGTCCGCCTAATGAGTTGAAACCAATGTTT
GTGGAACAAGTACGTCCTTTACTAGAGGAACGTTTTCCTTCTGAAGAAAAACTAATTTCTAAAGTTTTGCGCTTTTATGG
GATTGGTGAATCGCGACTGGTCACTGAGCTAAAAGATCTGATTGAGACACAGATCAATCCAACGATCGCACCATATGCCA
AACCAAATGAAGTGACATTACGACTGACAGTGAAAACAAATGATGTTCAGGCAGGGAATCAAGCTCTTTTAGCATTAGAA
GAAAAAATCCAAGAACGAGTAGGGGAATATTTTTATGGATACGGCGATGATAATTCGCTAGCAAAAGTCGTAGTGGAACT
ACTGAAAGAAAACAAGCAGACTGTAACAGCAGCGGAAAGTTTGACAGCCGGCGCCTTCCAAGCCGCATTAGGCGACATTG
CTGGTGTATCTGAAGTATTTCCAGGCGGATTCGTTACCTACTCGCTCCAAACAAAAGCTGGTTTTCTGGAGATTGATCCG
GAGCTATTAGCAGAATATGGAACAGTCAGCAAAGAATGTGTGGAGCAGATGGCCATTCAAGCACGTGAGATAGCAAGAAC
AGATTACAGTGTAGCTTTCACCGGAGTGGCTGGACCGGACACGTTAGAAGGTCAATCTGCAGGAACAGTATGGATCGCTA
TTTCATCTAAAGACGGCGTGGTTTCGGAAAAATATCACTTTGCCAGAGATCGTGCTGCTATCAGATATAATGCGGTTATG
CAAGGATTTGATCTTTTGAGAAAACAGCTTTTAAGAAAATGA

Domains

Predicted by InterproScan.

Competence-damaged protein (CinA)

(258-410)

Probable molybdopterin binding domain (MoCF_biosynth)

(5-169)

Damage-inducible protein CinA KH domain (CinA_KH)

(180-253)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cinA Streptococcus mitis SK321

51.19

100

0.521
  cinA Streptococcus mutans UA159

51.566

100

0.518
  cinA Streptococcus pneumoniae TIGR4

50.952

100

0.518
  cinA Streptococcus pneumoniae D39

50.714

100

0.516
  cinA Streptococcus pneumoniae R6

50.714

100

0.516
  cinA Streptococcus pneumoniae Rx1

50.714

100

0.516
  cinA Streptococcus mitis NCTC 12261

50.714

100

0.516
  cinA Bacillus subtilis subsp. subtilis str. 168

47.573

99.758

0.475
  cinA Streptococcus suis isolate S10

41.787

100

0.419