Detailed information    

insolico Bioinformatically predicted

Overview

Name   cinA   Type   Machinery gene
Locus tag   KGS74_RS04570 Genome accession   NZ_CP074377
Coordinates   1008250..1009491 (-) Length   413 a.a.
NCBI ID   WP_049169077.1    Uniprot ID   -
Organism   Lacticaseibacillus casei strain FBL6     
Function   facilitate localization of RecA (predicted from homology)   
Homologous recombination

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
ICE 994845..1016978 1008250..1009491 within 0


Gene organization within MGE regions


Location: 994845..1016978
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  KGS74_RS04515 (KGS74_04515) - 994845..995738 (+) 894 WP_049171184.1 IS3 family transposase -
  KGS74_RS04520 (KGS74_04520) ftsX 995884..996771 (-) 888 WP_049169073.1 permease-like cell division protein FtsX -
  KGS74_RS04525 (KGS74_04525) ftsE 996761..997447 (-) 687 WP_025012520.1 cell division ATP-binding protein FtsE -
  KGS74_RS04535 (KGS74_04535) secA 998900..1001263 (-) 2364 WP_039638826.1 preprotein translocase subunit SecA -
  KGS74_RS04540 (KGS74_04540) raiA 1001532..1002089 (-) 558 WP_010489439.1 ribosome-associated translation inhibitor RaiA -
  KGS74_RS04545 (KGS74_04545) - 1002214..1002732 (-) 519 WP_025012517.1 ComF family protein -
  KGS74_RS04550 (KGS74_04550) - 1002890..1004152 (-) 1263 WP_049169074.1 DEAD/DEAH box helicase -
  KGS74_RS04555 (KGS74_04555) - 1004180..1004833 (+) 654 WP_049169075.1 YigZ family protein -
  KGS74_RS04560 (KGS74_04560) rny 1004979..1006550 (-) 1572 WP_010489446.1 ribonuclease Y -
  KGS74_RS04565 (KGS74_04565) recA 1007209..1008195 (-) 987 Protein_895 recombinase RecA -
  KGS74_RS04570 (KGS74_04570) cinA 1008250..1009491 (-) 1242 WP_049169077.1 competence/damage-inducible protein A Machinery gene
  KGS74_RS04575 (KGS74_04575) pgsA 1009763..1010356 (-) 594 WP_025012513.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  KGS74_RS04580 (KGS74_04580) - 1010353..1011291 (-) 939 WP_049169078.1 helix-turn-helix domain-containing protein -
  KGS74_RS04585 (KGS74_04585) - 1011378..1012106 (-) 729 WP_049169079.1 SDR family oxidoreductase -
  KGS74_RS04590 (KGS74_04590) - 1012103..1013398 (-) 1296 WP_049169080.1 pitrilysin family protein -
  KGS74_RS04595 (KGS74_04595) - 1013395..1014657 (-) 1263 WP_049169081.1 pitrilysin family protein -
  KGS74_RS04600 (KGS74_04600) - 1014666..1016978 (-) 2313 WP_049169082.1 DNA translocase FtsK -

Sequence

Protein


Download         Length: 413 a.a.        Molecular weight: 44290.73 Da        Isoelectric Point: 6.6420

>NTDB_id=564435 KGS74_RS04570 WP_049169077.1 1008250..1009491(-) (cinA) [Lacticaseibacillus casei strain FBL6]
MQAEIIAVGTEILMGQITNTNGAYMAKQLAALGIASYHQQVVGDNAQRLADAISLAEKRSDIVILIGGLGPTPDDLTKQT
LAAHLNLPLVEDADAMAKLAARVKQQQRPMTPNNKLQAMYPQGADILVNRIGLAVGAWVEQHQHAYVLLPGPPKEFIPMV
DHELLPHLAKYSGHHEAFVSRVMRFFGVGESQLVTDLGDLIAKQTNPTLATYIKDHEVTIRVTASGETQTDAEAKLEPVI
RAIMDREGRYFYGYGDDNSLAKELVKALAATDKQITAAESLTAGAFQAALGDVPGVSNYFKGGFVTYALATKAAFLNIDA
RELAAHGVVSEFTAKAMAEHARQRAAADIAVSFTGVAGPDTLEGQPAGTVWIGLARMGQAPVAQVYHFPGGRNDVRKRAV
MTGMMIALKSLRD

Nucleotide


Download         Length: 1242 bp        

>NTDB_id=564435 KGS74_RS04570 WP_049169077.1 1008250..1009491(-) (cinA) [Lacticaseibacillus casei strain FBL6]
ATGCAGGCAGAAATTATTGCTGTCGGAACTGAAATTCTGATGGGACAGATTACTAATACTAATGGCGCCTATATGGCTAA
ACAGTTGGCCGCTTTAGGCATTGCCAGCTATCATCAACAGGTTGTCGGTGACAATGCGCAACGCCTGGCTGATGCGATCA
GCTTAGCCGAAAAACGCAGTGACATTGTGATTTTGATCGGTGGTTTAGGACCCACACCAGATGACCTGACGAAACAAACG
TTGGCGGCTCATCTGAATTTGCCGTTGGTTGAAGATGCGGACGCCATGGCAAAACTGGCGGCGCGGGTTAAACAACAGCA
ACGGCCGATGACGCCAAATAATAAGTTACAGGCGATGTATCCGCAAGGTGCTGATATATTGGTTAATCGCATCGGGCTGG
CAGTCGGTGCCTGGGTCGAACAACACCAACATGCCTATGTACTACTGCCTGGGCCGCCTAAGGAATTTATCCCAATGGTT
GATCATGAGCTATTGCCTCATTTGGCCAAGTATAGCGGCCATCATGAAGCTTTTGTCAGCCGCGTCATGCGCTTCTTTGG
TGTTGGTGAATCACAATTGGTGACGGATTTGGGTGATTTAATTGCCAAGCAGACGAATCCGACACTGGCAACGTATATCA
AGGATCATGAAGTGACCATTCGAGTGACGGCTAGTGGTGAGACCCAGACAGACGCTGAAGCAAAATTGGAACCGGTGATT
CGCGCCATTATGGATCGCGAGGGACGTTACTTTTATGGTTATGGTGATGATAATAGCCTCGCTAAAGAGTTGGTCAAGGC
ATTAGCGGCGACCGACAAGCAAATAACGGCAGCGGAGAGCTTGACAGCCGGTGCGTTTCAGGCAGCTTTGGGGGATGTTC
CCGGCGTCTCGAATTATTTCAAAGGCGGTTTTGTGACGTACGCCTTAGCCACTAAAGCAGCATTTTTGAATATTGATGCG
CGTGAGTTAGCGGCTCATGGGGTAGTGAGTGAATTTACTGCCAAAGCAATGGCCGAGCATGCCCGTCAGCGGGCTGCGGC
CGATATTGCAGTCAGTTTTACCGGCGTGGCAGGGCCCGACACACTGGAAGGCCAGCCAGCGGGGACAGTTTGGATCGGCT
TGGCGCGGATGGGCCAGGCGCCGGTTGCACAGGTTTATCATTTTCCCGGTGGCCGCAATGATGTGCGCAAACGCGCGGTT
ATGACTGGCATGATGATCGCATTGAAGAGCTTGCGGGATTAA

Domains

Predicted by InterproScan.

Damage-inducible protein CinA KH domain (CinA_KH)

(180-253)

Competence-damaged protein (CinA)

(258-409)

Probable molybdopterin binding domain (MoCF_biosynth)

(5-169)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cinA Streptococcus mitis SK321

50.831

100

0.518
  cinA Streptococcus mitis NCTC 12261

50.831

100

0.518
  cinA Streptococcus pneumoniae TIGR4

50.119

100

0.511
  cinA Streptococcus mutans UA159

50.725

100

0.508
  cinA Streptococcus pneumoniae Rx1

49.644

100

0.506
  cinA Streptococcus pneumoniae R6

49.644

100

0.506
  cinA Streptococcus pneumoniae D39

49.406

100

0.504
  cinA Bacillus subtilis subsp. subtilis str. 168

44.769

99.516

0.446
  cinA Streptococcus suis isolate S10

42.147

92.494

0.39