Detailed information    

insolico Bioinformatically predicted

Overview

Name   cinA   Type   Machinery gene
Locus tag   KFU60_RS00365 Genome accession   NZ_CP073916
Coordinates   62868..64109 (+) Length   413 a.a.
NCBI ID   WP_016387106.1    Uniprot ID   A0A422ME13
Organism   Lacticaseibacillus paracasei subsp. tolerans strain 2A     
Function   facilitate localization of RecA (predicted from homology)   
Homologous recombination

Genomic Context

Location: 57868..69109
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  KFU60_RS00345 (KFU60_00345) - 58867..60159 (+) 1293 WP_003661348.1 pitrilysin family protein -
  KFU60_RS00350 (KFU60_00350) - 60159..60887 (+) 729 WP_003569514.1 SDR family oxidoreductase -
  KFU60_RS00355 (KFU60_00355) - 60974..61903 (+) 930 WP_003593861.1 helix-turn-helix domain-containing protein -
  KFU60_RS00360 (KFU60_00360) pgsA 61900..62493 (+) 594 WP_003564171.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  KFU60_RS00365 (KFU60_00365) cinA 62868..64109 (+) 1242 WP_016387106.1 competence/damage-inducible protein A Machinery gene
  KFU60_RS00370 (KFU60_00370) recA 64166..65227 (+) 1062 WP_108298964.1 recombinase RecA Machinery gene
  KFU60_RS00375 (KFU60_00375) rny 65529..67100 (+) 1572 WP_003657913.1 ribonuclease Y -
  KFU60_RS00380 (KFU60_00380) - 67194..67844 (-) 651 WP_108298965.1 YigZ family protein -

Sequence

Protein


Download         Length: 413 a.a.        Molecular weight: 44312.66 Da        Isoelectric Point: 6.0028

>NTDB_id=562261 KFU60_RS00365 WP_016387106.1 62868..64109(+) (cinA) [Lacticaseibacillus paracasei subsp. tolerans strain 2A]
MQAEIIAVGTEILMGQITNTNGAYMAKQLTALGIDSYHQQVVGDNGPRLEEAIKLAESRSNLVILIGGLGPTPDDLTKQT
LAAHLNRKLVEDPDAMAKLQARVKQQQRPMTPNNQLQAMYPEGADILVNRVGLAVGAWIVNGQHTYVLLPGPPKEFVPMV
DHELLPRLAKWSGHAEIMVSRVLRFFGIGESQLVTDLDDLIANQTDPTIATYIKDHEVTVRVTASGATEKDADAKLEPMI
GAIMDRDGQYFYGYGDDNSLAKEVVKTLAANDMQITAAESLTAGAFQAALGDVPGVSTYFKGGFVTYSLATKAAFLAIDA
RELAAHGVVSAFTAKAMAEHARRKAAADISVSFTGVAGPDTLEGQPAGTVWIGLARRGQLPEAHVYHFPGGRNDVRQRAV
MTGMMLALRALQA

Nucleotide


Download         Length: 1242 bp        

>NTDB_id=562261 KFU60_RS00365 WP_016387106.1 62868..64109(+) (cinA) [Lacticaseibacillus paracasei subsp. tolerans strain 2A]
ATGCAAGCAGAGATTATTGCTGTCGGGACAGAGATCCTGATGGGACAGATTACTAACACAAATGGTGCCTATATGGCTAA
GCAACTGACAGCACTGGGTATTGATAGCTACCATCAACAGGTGGTGGGAGACAACGGGCCGCGACTTGAGGAGGCCATTA
AGTTGGCGGAAAGTCGCAGTAATTTAGTTATTTTGATTGGCGGGTTAGGACCGACACCAGATGATCTGACCAAGCAAACA
TTGGCAGCGCACTTGAACCGCAAATTGGTTGAAGATCCTGACGCTATGGCTAAATTACAGGCGCGCGTCAAGCAACAGCA
GCGGCCAATGACGCCTAATAATCAATTACAGGCCATGTATCCGGAAGGCGCCGATATTTTGGTCAATCGGGTTGGCTTAG
CGGTTGGCGCGTGGATCGTCAATGGGCAGCACACCTATGTCTTATTGCCGGGACCACCGAAGGAATTCGTTCCGATGGTT
GATCATGAACTGCTGCCGCGGCTAGCAAAATGGAGCGGCCACGCGGAAATTATGGTCAGCCGGGTCTTACGTTTCTTTGG
CATTGGCGAATCGCAACTAGTGACAGATCTGGACGACTTGATTGCCAACCAAACCGATCCGACCATTGCAACTTATATCA
AGGATCATGAGGTGACGGTGCGCGTCACTGCCAGTGGCGCTACCGAAAAAGACGCTGATGCAAAGTTAGAACCAATGATC
GGTGCCATCATGGATCGTGATGGTCAATATTTTTACGGCTACGGTGACGACAATAGTTTGGCAAAAGAGGTTGTGAAGAC
GCTTGCGGCAAATGATATGCAAATTACTGCAGCTGAGAGTTTGACTGCTGGCGCATTTCAAGCAGCGTTAGGCGATGTGC
CGGGGGTATCCACTTATTTTAAGGGCGGTTTTGTCACTTACTCACTTGCAACAAAGGCCGCTTTTTTGGCAATTGATGCT
CGCGAATTAGCGGCACACGGAGTTGTCAGCGCATTTACAGCCAAGGCGATGGCTGAACATGCTCGGCGTAAGGCAGCGGC
GGATATAAGTGTCAGCTTTACCGGCGTTGCCGGTCCAGACACGCTGGAAGGACAGCCTGCTGGTACGGTTTGGATCGGTT
TAGCGCGGCGTGGCCAACTGCCTGAAGCACATGTTTACCATTTTCCTGGCGGTCGCAATGATGTTCGGCAGCGTGCTGTG
ATGACTGGTATGATGCTTGCATTAAGGGCGCTGCAGGCCTAA

Domains

Predicted by InterproScan.

Probable molybdopterin binding domain (MoCF_biosynth)

(5-169)

Damage-inducible protein CinA KH domain (CinA_KH)

(180-253)

Competence-damaged protein (CinA)

(258-410)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A422ME13

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cinA Streptococcus mitis NCTC 12261

52.123

100

0.535
  cinA Streptococcus mitis SK321

52.009

100

0.533
  cinA Streptococcus pneumoniae TIGR4

51.651

100

0.53
  cinA Streptococcus pneumoniae R6

51.179

100

0.525
  cinA Streptococcus pneumoniae Rx1

51.179

100

0.525
  cinA Streptococcus mutans UA159

52.415

100

0.525
  cinA Streptococcus pneumoniae D39

50.943

100

0.523
  cinA Bacillus subtilis subsp. subtilis str. 168

44.769

99.516

0.446
  cinA Streptococcus suis isolate S10

42.328

91.525

0.387