Detailed information NTG0553305

Bioinformatically predicted

Overview

• Name: comGA/cglA/cilD
• Type: Machinery gene
• Locus tag: J7T61_RS08860
• Genome accession: NZ_CP072441
• Coordinates: 1686450..1687391 (-)
• Length: 313 a.a.
• NCBI ID: WP_071417491.1
• Uniprot ID: -
• Organism: Streptococcus thermophilus strain S24728
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type	MGE coordinates	Gene coordinates	Relative position	Distance (bp)
IScluster/Tn	1688104..1689359	1686450..1687391	flank	713

Gene organization within MGE regions

Location: 1686450..1689359

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
J7T61_RS08860 (J7T61_08795)	comGA/cglA/cilD	1686450..1687391 (-)	942	WP_071417491.1	competence type IV pilus ATPase ComGA	Machinery gene
J7T61_RS08865 (J7T61_08800)	-	1687472..1687834 (-)	363	WP_014622006.1	DUF1033 family protein	-
J7T61_RS08870 (J7T61_08805)	-	1688104..1689352 (+)	1249	Protein_1690	ISL3 family transposase	-

Sequence

Protein

• Length: 313 a.a.
• Molecular weight: 35411.58 Da
• Isoelectric Point: 6.4142

>NTDB_id=553305 J7T61_RS08860 WP_071417491.1 1686450..1687391(-) (comGA/cglA/cilD) [Streptococcus thermophilus strain S24728]
MVTEFAKEMIKNADSCGAQDIYVIPRQDNYELYMRVGQERRLIDVYRPDFMASLIGHFKFVAGMMVGEKRRSQLGSCDYD
CGDGHLVSLRLSTVGDYRGLESLVIRILHSERRELVYWNQGIHPIKDALDYRGLYLFAGPVGSGKTTLMHELVQEHFKGQ
QVISIEDPVEIKQDNVLQLQVNQAIDMTYDSLIKLSLRHRPDVLIIGEIRDKETARAVIRASLIGVTVLSTIHAKSIAGV
YERLLDLGVDKSELDNALQGIAYMRLIKGGGVIDFARENFQNHSSTNWNQQLEGLVKQGCLTERDIQGEKIKD

Nucleotide

• Length: 942 bp

>NTDB_id=553305 J7T61_RS08860 WP_071417491.1 1686450..1687391(-) (comGA/cglA/cilD) [Streptococcus thermophilus strain S24728]
ATGGTAACAGAATTTGCTAAGGAAATGATCAAAAATGCTGATAGTTGTGGGGCTCAAGACATCTATGTCATTCCACGTCA
GGATAATTATGAGCTCTATATGCGAGTCGGGCAAGAGAGGAGATTGATTGATGTATATCGGCCTGATTTCATGGCTAGTC
TTATTGGTCACTTTAAATTTGTGGCGGGAATGATGGTGGGTGAGAAGCGTAGGAGTCAACTGGGTTCATGTGACTATGAT
TGTGGTGACGGTCACTTGGTTTCTCTGCGTTTATCAACTGTTGGAGACTATCGAGGTTTGGAGAGCTTGGTTATCCGTAT
CCTACATTCCGAACGTCGAGAATTAGTGTATTGGAATCAAGGAATCCATCCTATTAAGGATGCCTTGGATTATAGAGGAC
TGTATCTCTTTGCGGGTCCCGTAGGTTCTGGGAAGACCACACTTATGCATGAGTTGGTTCAGGAGCATTTTAAGGGGCAG
CAGGTAATTTCGATTGAGGATCCTGTTGAAATCAAACAGGATAATGTCTTGCAACTCCAGGTTAATCAGGCGATTGATAT
GACCTATGATAGTTTGATTAAGCTATCTCTACGTCACCGTCCAGATGTTTTGATTATTGGGGAGATTCGGGATAAGGAGA
CTGCCCGGGCAGTTATTAGAGCTAGTCTAATAGGTGTAACTGTTCTTTCAACTATTCATGCTAAGAGTATTGCTGGCGTT
TACGAACGTCTCTTGGACCTTGGCGTAGATAAGTCTGAGTTGGATAATGCTCTACAAGGCATTGCCTACATGCGTTTGAT
CAAGGGAGGAGGTGTGATTGATTTTGCCAGAGAAAATTTCCAAAACCATTCGTCGACCAACTGGAATCAGCAGTTGGAAG
GTTTGGTTAAACAAGGATGTCTCACTGAGAGGGATATCCAAGGGGAAAAAATTAAAGATTAG

Domains

Predicted by InterproScan.

• Type II/IV secretion system protein (T2SSE) (10-267)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comGA/cglA/cilD	Streptococcus mitis NCTC 12261	65.273	99.361	0.649
comYA	Streptococcus mutans UA159	64.217	100	0.642
comYA	Streptococcus mutans UA140	64.217	100	0.642
comGA/cglA/cilD	Streptococcus pneumoniae D39	63.987	99.361	0.636
comGA/cglA/cilD	Streptococcus pneumoniae Rx1	63.987	99.361	0.636
comGA/cglA/cilD	Streptococcus pneumoniae R6	63.987	99.361	0.636
comGA/cglA/cilD	Streptococcus pneumoniae TIGR4	63.987	99.361	0.636
comYA	Streptococcus gordonii str. Challis substr. CH1	62.939	100	0.629
comGA/cglA	Streptococcus sobrinus strain NIDR 6715-7	61.218	99.681	0.61
comGA	Lactococcus lactis subsp. cremoris KW2	51.125	99.361	0.508
comGA	Latilactobacillus sakei subsp. sakei 23K	38.667	95.847	0.371