Detailed information NTG0552832

Bioinformatically predicted

Overview

• Name: comGA/cglA/cilD
• Type: Machinery gene
• Locus tag: J7U07_RS08860
• Genome accession: NZ_CP072433
• Coordinates: 1700909..1701850 (-)
• Length: 313 a.a.
• NCBI ID: WP_014727726.1
• Uniprot ID: -
• Organism: Streptococcus thermophilus strain S24743
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type	MGE coordinates	Gene coordinates	Relative position	Distance (bp)
IS/Tn	1702563..1703819	1700909..1701850	flank	713

Gene organization within MGE regions

Location: 1700909..1703819

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
J7U07_RS08860 (J7U07_08740)	comGA/cglA/cilD	1700909..1701850 (-)	942	WP_014727726.1	competence type IV pilus ATPase ComGA	Machinery gene
J7U07_RS08865 (J7U07_08745)	-	1701931..1702293 (-)	363	WP_014622006.1	DUF1033 family protein	-
J7U07_RS08870 (J7U07_08750)	-	1702563..1703812 (+)	1250	Protein_1690	ISL3 family transposase	-

Sequence

Protein

• Length: 313 a.a.
• Molecular weight: 35524.70 Da
• Isoelectric Point: 6.6091

>NTDB_id=552832 J7U07_RS08860 WP_014727726.1 1700909..1701850(-) (comGA/cglA/cilD) [Streptococcus thermophilus strain S24743]
MVTEFAKEMIKNADSCGAQDIYVIPRQDNYELYMRVGQERRLIDVYRPDFMASLIGHFKFVARMMVGEKRRSQLGSCDYD
CGDGHLVSLRLSTVGDYRGLESLVIRILHSERRELVYWNQGIQPIKDALDYRGLYLFAGPVGSGKTTLMHELVQERFKGQ
QVISIEDPVEIKQDNVLQLQVNQAIDMTYDSLIKLSLRHRPDVLIIGEIRDKETARAVIRASLTGVTVLSTIHAKSIAGV
YERLLDLGVDKSELDNALQGISYMRLIKGGGVIDFARENFQNHSSTNWNQQLEGLVKQGCLTERDIQGEKIKD

Nucleotide

• Length: 942 bp

>NTDB_id=552832 J7U07_RS08860 WP_014727726.1 1700909..1701850(-) (comGA/cglA/cilD) [Streptococcus thermophilus strain S24743]
ATGGTAACAGAATTTGCTAAGGAAATGATCAAAAATGCTGATAGTTGTGGGGCTCAAGACATCTATGTCATTCCACGTCA
GGATAATTATGAGCTCTATATGCGAGTCGGGCAAGAGAGGAGATTGATTGATGTATATCGGCCTGATTTCATGGCTAGTC
TTATTGGTCACTTTAAATTTGTGGCGAGAATGATGGTGGGTGAGAAGCGTAGGAGTCAACTGGGTTCATGTGACTATGAT
TGTGGTGACGGTCACTTGGTTTCTCTGCGTTTATCAACTGTTGGAGACTATCGAGGTTTGGAGAGCTTGGTTATCCGTAT
CCTACATTCCGAACGTCGAGAATTGGTGTATTGGAATCAAGGAATCCAGCCTATTAAGGATGCCTTGGATTATAGAGGAC
TGTATCTCTTTGCGGGTCCCGTAGGTTCTGGGAAGACCACACTTATGCATGAGTTGGTTCAGGAGCGTTTTAAGGGGCAG
CAGGTAATTTCGATTGAGGATCCTGTTGAAATCAAACAGGATAATGTCTTGCAACTCCAGGTTAATCAGGCGATTGATAT
GACCTATGATAGTTTGATTAAGCTATCTCTACGTCACCGTCCAGATGTTTTGATTATTGGGGAGATTCGGGATAAGGAGA
CTGCCCGGGCAGTTATTAGAGCTAGTCTAACAGGTGTAACTGTTCTTTCAACTATTCATGCTAAGAGTATTGCTGGCGTT
TACGAACGTCTCTTGGACCTTGGCGTAGATAAGTCTGAGTTGGATAATGCTCTACAAGGCATTTCCTACATGCGTTTGAT
CAAGGGAGGAGGTGTGATTGATTTTGCCAGAGAAAATTTCCAAAACCATTCGTCGACCAACTGGAATCAGCAGTTGGAAG
GTTTGGTTAAACAAGGATGTCTCACTGAGAGGGATATCCAAGGGGAAAAAATTAAAGATTAG

Domains

Predicted by InterproScan.

• Type II/IV secretion system protein (T2SSE) (10-266)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comGA/cglA/cilD	Streptococcus mitis NCTC 12261	65.273	99.361	0.649
comYA	Streptococcus mutans UA159	64.537	100	0.645
comYA	Streptococcus mutans UA140	64.537	100	0.645
comGA/cglA/cilD	Streptococcus pneumoniae D39	63.987	99.361	0.636
comGA/cglA/cilD	Streptococcus pneumoniae Rx1	63.987	99.361	0.636
comGA/cglA/cilD	Streptococcus pneumoniae R6	63.987	99.361	0.636
comGA/cglA/cilD	Streptococcus pneumoniae TIGR4	63.987	99.361	0.636
comYA	Streptococcus gordonii str. Challis substr. CH1	62.939	100	0.629
comGA/cglA	Streptococcus sobrinus strain NIDR 6715-7	60.897	99.681	0.607
comGA	Lactococcus lactis subsp. cremoris KW2	50.804	99.361	0.505
comGA	Latilactobacillus sakei subsp. sakei 23K	38.158	97.125	0.371