Detailed information    

insolico Bioinformatically predicted

Overview

Name   cinA   Type   Machinery gene
Locus tag   J7T78_RS00410 Genome accession   NZ_CP072427
Coordinates   70943..72214 (+) Length   423 a.a.
NCBI ID   WP_014621015.1    Uniprot ID   -
Organism   Streptococcus thermophilus strain S24750     
Function   facilitate localization of RecA (predicted from homology)   
Homologous recombination

Genomic Context

Location: 65943..77214
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  J7T78_RS00380 (J7T78_00375) - 66278..66669 (-) 392 Protein_54 LytTR family DNA-binding domain-containing protein -
  J7T78_RS00385 (J7T78_00380) - 66893..67198 (+) 306 WP_014621013.1 hypothetical protein -
  J7T78_RS00390 (J7T78_00385) mutL 67250..69193 (+) 1944 WP_011680601.1 DNA mismatch repair endonuclease MutL -
  J7T78_RS00395 (J7T78_00390) - 69323..69544 (+) 222 WP_011680602.1 hypothetical protein -
  J7T78_RS00400 (J7T78_00395) ruvA 69696..70286 (+) 591 WP_011680603.1 Holliday junction branch migration protein RuvA -
  J7T78_RS00405 (J7T78_00400) - 70293..70847 (+) 555 WP_014621014.1 DNA-3-methyladenine glycosylase I -
  J7T78_RS00410 (J7T78_00405) cinA 70943..72214 (+) 1272 WP_014621015.1 competence/damage-inducible protein A Machinery gene
  J7T78_RS00415 (J7T78_00410) recA 72250..73389 (+) 1140 WP_011680606.1 recombinase RecA Machinery gene
  J7T78_RS00420 (J7T78_00415) spx 73566..73964 (+) 399 WP_002949058.1 transcriptional regulator Spx -

Sequence

Protein


Download         Length: 423 a.a.        Molecular weight: 45952.38 Da        Isoelectric Point: 5.0948

>NTDB_id=552494 J7T78_RS00410 WP_014621015.1 70943..72214(+) (cinA) [Streptococcus thermophilus strain S24750]
MKAELIAVGTEILTGQITNTNAQFLSEKLAELGIDVYFHTAVGDNENRLLSVLDQSSKRSDLVILCGGLGPTEDDLTKQT
LAKFLGKELIFDEEASKKLDSFFATRPKHTRTPNNERQAQIVEGAVPLQNLTGLAVGGIITVEGVTYVVLPGPPSELKPM
VNQELIPALTENHTTLYSRVLRFFGVGESQLVTIIKDLIVNQTDPTIAPYAKVGEVTLRLSTKASSQEEADRKLDVLEEQ
IRSTKTLDGKSLSDLIYGYGESNSLAYEVFYLLKKYGKTITAAESLTAGLFQASVADFPGASQVFKGGFVTYSMEEKAKM
LGIPLSKLEEHGVVSHFTAEKMAEGARVKTDSDYGIALTGVAGPDALEGHQAGTVFIGIADRNQVRSIKVVIGGRSRSDV
RYISTLYAFNLVRQALLQEDNLI

Nucleotide


Download         Length: 1272 bp        

>NTDB_id=552494 J7T78_RS00410 WP_014621015.1 70943..72214(+) (cinA) [Streptococcus thermophilus strain S24750]
ATGAAAGCTGAATTGATTGCAGTAGGAACTGAAATTCTTACAGGGCAAATCACCAATACCAATGCCCAATTTTTATCTGA
AAAACTAGCTGAATTAGGAATTGACGTGTATTTTCACACAGCGGTAGGAGACAATGAAAACCGTCTACTTTCAGTCTTAG
ACCAGTCTAGTAAACGTAGCGATTTAGTCATACTCTGTGGAGGACTTGGCCCTACTGAGGATGACTTAACCAAACAAACA
TTGGCTAAGTTTTTAGGCAAAGAACTCATTTTTGATGAGGAGGCAAGTAAAAAACTGGATAGTTTCTTTGCTACTCGTCC
TAAACATACACGAACGCCTAATAATGAACGCCAAGCGCAAATTGTTGAGGGGGCTGTCCCCTTGCAAAATCTCACAGGTC
TGGCAGTTGGAGGAATTATTACTGTTGAAGGAGTGACCTATGTTGTCTTGCCTGGTCCGCCAAGTGAACTCAAACCTATG
GTGAACCAAGAGCTTATTCCAGCTCTCACAGAGAATCATACTACGCTTTATTCTAGAGTCCTAAGGTTTTTTGGTGTTGG
AGAAAGTCAATTGGTGACTATTATTAAAGATCTCATTGTTAACCAAACAGACCCAACCATTGCGCCCTATGCTAAAGTGG
GAGAAGTGACCCTTCGCTTATCAACAAAGGCATCGTCGCAAGAAGAAGCGGATCGAAAACTAGATGTTTTAGAAGAACAA
ATTCGTTCTACTAAAACTCTAGATGGAAAAAGCTTGTCTGATCTCATCTATGGATATGGAGAATCAAATAGCTTAGCTTA
TGAAGTGTTCTATTTGCTTAAGAAATATGGCAAAACTATTACTGCAGCTGAAAGTTTAACAGCTGGCTTATTTCAAGCTA
GTGTTGCTGATTTTCCTGGAGCTTCACAAGTATTCAAGGGTGGTTTTGTCACCTATAGCATGGAAGAAAAAGCTAAAATG
TTGGGTATTCCCTTATCTAAATTAGAAGAGCATGGTGTTGTTAGTCATTTTACAGCAGAAAAAATGGCTGAGGGTGCCCG
AGTTAAGACAGATAGTGATTACGGAATTGCGCTTACTGGAGTAGCAGGACCAGATGCTTTGGAAGGGCATCAAGCAGGTA
CAGTCTTTATTGGTATTGCCGATAGAAACCAAGTGCGATCAATTAAGGTTGTTATAGGTGGAAGAAGTCGATCTGATGTT
AGATATATCAGTACACTCTATGCCTTTAACCTAGTTCGCCAAGCTTTATTACAAGAGGACAACTTAATTTAA

Domains

Predicted by InterproScan.

Competence-damaged protein (CinA)

(264-415)

Damage-inducible protein CinA KH domain (CinA_KH)

(178-243)

Probable molybdopterin binding domain (MoCF_biosynth)

(5-170)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cinA Streptococcus mitis SK321

74.702

99.054

0.74
  cinA Streptococcus mitis NCTC 12261

73.508

99.054

0.728
  cinA Streptococcus pneumoniae TIGR4

72.315

99.054

0.716
  cinA Streptococcus pneumoniae Rx1

72.076

99.054

0.714
  cinA Streptococcus pneumoniae R6

72.076

99.054

0.714
  cinA Streptococcus pneumoniae D39

71.838

99.054

0.712
  cinA Streptococcus mutans UA159

70.213

100

0.702
  cinA Streptococcus suis isolate S10

54.567

98.345

0.537
  cinA Bacillus subtilis subsp. subtilis str. 168

44.656

99.527

0.444