Detailed information    

insolico Bioinformatically predicted

Overview

Name   comE/comE2   Type   Regulator
Locus tag   J4854_RS10295 Genome accession   NZ_CP072329
Coordinates   2141361..2142119 (-) Length   252 a.a.
NCBI ID   WP_187538542.1    Uniprot ID   -
Organism   Streptococcus lactarius strain CCUG 66490     
Function   activate transcription of early competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2136361..2147119
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  J4854_RS10275 (J4854_10275) - 2136814..2138433 (+) 1620 WP_200772348.1 ATP-binding cassette domain-containing protein -
  J4854_RS10280 (J4854_10280) - 2138489..2141101 (+) 2613 WP_200772347.1 YfhO family protein -
  J4854_RS10295 (J4854_10295) comE/comE2 2141361..2142119 (-) 759 WP_187538542.1 response regulator transcription factor Regulator
  J4854_RS10300 (J4854_10300) - 2142116..2143456 (-) 1341 WP_200772346.1 sensor histidine kinase -

Sequence

Protein


Download         Length: 252 a.a.        Molecular weight: 29611.94 Da        Isoelectric Point: 5.0990

>NTDB_id=552070 J4854_RS10295 WP_187538542.1 2141361..2142119(-) (comE/comE2) [Streptococcus lactarius strain CCUG 66490]
MKIFLLEDELQQQLRVEKHIATIANELDLTIEMISTGKLSEFEEYIQHSDLHQLYFLDIHIQDNEYCGLEIAQKIREANP
YAIIVFITTKSEFASITYRYKVSALDFIDKNLNEDLFKSKLQGCIEYLTTIQIKNDDLTDYFEYDFRDKKIKIPFKDILY
IETIGTAYKLNLVGKNFQKEIAGSLSDVLNKDEEDRYFSPHQSFIVNRSMIIGMDKKNKQLLLKEGYSCPISRSNIKRVK
KLIEEQNLEYNA

Nucleotide


Download         Length: 759 bp        

>NTDB_id=552070 J4854_RS10295 WP_187538542.1 2141361..2142119(-) (comE/comE2) [Streptococcus lactarius strain CCUG 66490]
ATGAAGATTTTTTTACTAGAAGATGAACTACAACAACAGCTACGTGTTGAAAAACATATTGCAACAATTGCTAACGAATT
GGATTTAACGATTGAAATGATTTCTACAGGTAAGCTATCTGAGTTTGAAGAATATATACAACATTCTGATCTCCACCAAT
TATATTTTTTAGATATTCATATTCAAGACAATGAGTATTGTGGGCTCGAAATTGCTCAAAAAATACGGGAAGCAAATCCT
TATGCAATTATTGTATTCATTACTACAAAATCTGAATTTGCCTCTATTACTTACCGTTACAAAGTATCTGCTTTGGACTT
TATTGATAAAAATTTGAATGAAGATTTATTTAAATCTAAGTTACAAGGTTGTATTGAATATTTGACAACCATCCAGATTA
AAAATGATGACTTGACGGATTATTTTGAGTATGACTTTAGGGATAAAAAAATTAAAATTCCGTTCAAAGATATTCTTTAT
ATTGAGACGATTGGAACTGCTTATAAATTGAATTTAGTTGGAAAAAATTTTCAAAAAGAAATTGCGGGAAGCTTATCCGA
TGTTTTAAATAAGGATGAAGAAGATAGATATTTTAGCCCTCATCAATCTTTTATTGTAAATAGAAGTATGATTATTGGAA
TGGATAAGAAAAATAAGCAACTTCTCTTAAAAGAAGGATATTCTTGCCCTATTTCAAGAAGCAATATCAAGCGCGTTAAA
AAATTAATTGAAGAGCAAAATTTAGAATATAATGCTTGA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(20-120)

LytTr DNA-binding domain (LytTR)

(149-243)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comE/comE2 Streptococcus gordonii strain NCTC7865

49.194

98.413

0.484
  comE/comE1 Streptococcus gordonii str. Challis substr. CH1

49.194

98.413

0.484
  comE Streptococcus pneumoniae Rx1

46.371

98.413

0.456
  comE Streptococcus pneumoniae D39

46.371

98.413

0.456
  comE Streptococcus pneumoniae R6

46.371

98.413

0.456
  comE Streptococcus pneumoniae TIGR4

46.371

98.413

0.456
  comE Streptococcus mitis NCTC 12261

46.371

98.413

0.456
  comE Streptococcus mitis SK321

46.371

98.413

0.456
  comE Streptococcus infantis strain Atu-4

45.565

98.413

0.448
  comE/blpR Streptococcus mutans UA159

38.462

98.016

0.377