Detailed information    

insolico Bioinformatically predicted

Overview

Name   cinA   Type   Machinery gene
Locus tag   J5Z97_RS08765 Genome accession   NZ_CP072112
Coordinates   1768685..1769956 (-) Length   423 a.a.
NCBI ID   WP_208769267.1    Uniprot ID   -
Organism   Streptococcus pyogenes strain M08500     
Function   require for competence (predicted from homology)   
Unclear

Genomic Context

Location: 1763685..1774956
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  J5Z97_RS08740 (J5Z97_08740) - 1765655..1765960 (-) 306 WP_002982199.1 DUF1292 domain-containing protein -
  J5Z97_RS08745 (J5Z97_08745) ruvX 1765972..1766391 (-) 420 WP_002982196.1 Holliday junction resolvase RuvX -
  J5Z97_RS08750 (J5Z97_08750) - 1766388..1766657 (-) 270 WP_002982194.1 IreB family regulatory phosphoprotein -
  J5Z97_RS08755 (J5Z97_08755) spx 1766771..1767169 (-) 399 WP_002982188.1 transcriptional regulator Spx -
  J5Z97_RS08760 (J5Z97_08760) recA 1767460..1768596 (-) 1137 WP_002992179.1 recombinase RecA Machinery gene
  J5Z97_RS08765 (J5Z97_08765) cinA 1768685..1769956 (-) 1272 WP_208769267.1 competence/damage-inducible protein A Machinery gene
  J5Z97_RS08770 (J5Z97_08770) - 1770025..1770584 (-) 560 Protein_1672 DNA-3-methyladenine glycosylase I -
  J5Z97_RS08775 (J5Z97_08775) ruvA 1770594..1771190 (-) 597 WP_023611209.1 Holliday junction branch migration protein RuvA -
  J5Z97_RS08780 (J5Z97_08780) - 1771192..1772412 (-) 1221 WP_063662461.1 MFS transporter -
  J5Z97_RS08785 (J5Z97_08785) mutL 1772423..1774405 (-) 1983 WP_023611310.1 DNA mismatch repair endonuclease MutL -

Sequence

Protein


Download         Length: 423 a.a.        Molecular weight: 46071.80 Da        Isoelectric Point: 4.9081

>NTDB_id=550500 J5Z97_RS08765 WP_208769267.1 1768685..1769956(-) (cinA) [Streptococcus pyogenes strain M08500]
MKAELIAVGTEILTGQIVNTNAQFLSEKMAELGIDVYFQTAVGDNEERLLSVITTASQRSDLVILCGGLGPTKDDLTKQT
LAKYLRRDLVYDEQACQKLDDFFAKRKPSSRTPNNERQAQVIEGSIPLPNKTGLAVGGFITVDGISYVVLPGPPSELKPR
VNEELVPLLSKQYSTLYSKVLRFFGIGESQLVTVLSDFIENQTDPTIAPYAKTGEVTLRLSTKTENQALADKKLGQLEAQ
LLSRKTLEGQPLADVFYGYGEDNSLARETFELLVKYDKTITAAESLTAGLFQSTLASFPGASQVFNGGFVTYSMEEKAKM
LGLPLEELKSHGVVSAYTAEGMAEQARLLTGADIGVSLTGVAGPDMLEEQPAGTVFIGLATQNKVESIKVLISGRSRLDV
RYIATLHVFNMVRKTLLKLENLL

Nucleotide


Download         Length: 1272 bp        

>NTDB_id=550500 J5Z97_RS08765 WP_208769267.1 1768685..1769956(-) (cinA) [Streptococcus pyogenes strain M08500]
ATGAAAGCTGAACTGATTGCAGTAGGTACCGAAATTTTGACTGGTCAAATTGTGAATACCAATGCTCAATTTCTGTCGGA
AAAAATGGCAGAGCTAGGTATTGATGTCTATTTTCAAACGGCTGTTGGGGACAACGAGGAGCGTTTACTTTCAGTGATTA
CAACTGCTAGTCAGCGTAGTGACTTGGTCATTTTATGCGGTGGCCTTGGTCCAACGAAAGATGATTTAACCAAACAAACT
TTAGCAAAGTACCTTAGGAGAGACTTGGTTTATGATGAGCAAGCTTGTCAGAAACTAGATGACTTTTTTGCTAAGCGCAA
GCCTTCATCACGGACACCAAATAATGAGCGACAGGCACAAGTGATTGAAGGGTCAATCCCTTTGCCAAATAAAACTGGTC
TTGCGGTTGGTGGGTTCATTACAGTCGATGGTATTAGTTATGTTGTCTTACCGGGTCCTCCAAGTGAATTGAAGCCGAGG
GTAAATGAAGAATTGGTACCACTTCTGTCAAAACAATACAGTACATTGTATTCAAAGGTACTACGCTTTTTTGGTATTGG
GGAAAGTCAGTTGGTAACAGTCTTGTCAGATTTTATTGAGAATCAAACTGATCCAACCATTGCTCCGTATGCTAAGACTG
GCGAAGTGACTCTTCGCTTATCAACAAAAACTGAAAACCAAGCTCTGGCAGATAAAAAGTTAGGTCAGCTAGAAGCGCAG
CTACTATCCCGAAAAACTCTTGAAGGTCAACCCTTAGCTGATGTCTTTTATGGCTATGGAGAGGATAATTCCTTAGCGCG
TGAGACATTTGAGCTCTTAGTAAAATATGATAAGACAATTACAGCAGCAGAAAGTCTAACCGCGGGATTATTTCAGTCAA
CTTTGGCGAGTTTTCCAGGAGCTTCTCAAGTATTCAATGGAGGCTTTGTGACTTATAGCATGGAAGAAAAAGCGAAAATG
CTAGGCCTTCCTTTAGAGGAGTTGAAATCGCATGGCGTTGTTAGTGCTTATACAGCCGAGGGGATGGCGGAGCAAGCAAG
GTTATTGACTGGTGCTGATATTGGGGTAAGTTTAACAGGTGTTGCCGGACCAGATATGTTGGAGGAACAGCCTGCAGGTA
CAGTTTTCATTGGCCTTGCCACTCAAAATAAGGTAGAATCAATAAAGGTTTTGATTAGCGGGCGAAGTCGTTTGGATGTG
CGCTATATCGCTACTTTACATGTCTTTAATATGGTCCGTAAAACTTTATTAAAACTTGAGAATTTGCTATAA

Domains

Predicted by InterproScan.

Probable molybdopterin binding domain (MoCF_biosynth)

(5-170)

Competence-damaged protein (CinA)

(263-416)

Damage-inducible protein CinA KH domain (CinA_KH)

(178-243)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cinA Streptococcus mutans UA159

69.504

100

0.695
  cinA Streptococcus mitis SK321

69.305

98.582

0.683
  cinA Streptococcus mitis NCTC 12261

68.825

98.582

0.678
  cinA Streptococcus pneumoniae TIGR4

67.866

98.582

0.669
  cinA Streptococcus pneumoniae Rx1

67.866

98.582

0.669
  cinA Streptococcus pneumoniae R6

67.866

98.582

0.669
  cinA Streptococcus pneumoniae D39

67.626

98.582

0.667
  cinA Streptococcus suis isolate S10

52.885

98.345

0.52
  cinA Bacillus subtilis subsp. subtilis str. 168

46.651

98.818

0.461