Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilC   Type   Machinery gene
Locus tag   J2N86_RS08760 Genome accession   NZ_CP071527
Coordinates   1970587..1971819 (+) Length   410 a.a.
NCBI ID   WP_252579015.1    Uniprot ID   -
Organism   Legionella lytica strain PCM 2298     
Function   assembly of type IV pilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1965587..1976819
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  J2N86_RS08740 (J2N86_08755) - 1967029..1967589 (-) 561 WP_252579011.1 hypoxanthine-guanine phosphoribosyltransferase -
  J2N86_RS08745 (J2N86_08760) - 1967641..1967967 (-) 327 WP_252579012.1 DUF1820 family protein -
  J2N86_RS08750 (J2N86_08765) - 1968052..1968804 (-) 753 WP_252579013.1 methyltransferase domain-containing protein -
  J2N86_RS08755 (J2N86_08770) pilB 1968916..1970583 (+) 1668 WP_252579014.1 type IV-A pilus assembly ATPase PilB Machinery gene
  J2N86_RS08760 (J2N86_08775) pilC 1970587..1971819 (+) 1233 WP_252579015.1 type II secretion system F family protein Machinery gene
  J2N86_RS08765 (J2N86_08780) - 1971833..1972693 (+) 861 WP_252579016.1 A24 family peptidase -
  J2N86_RS08770 (J2N86_08785) - 1972852..1973607 (+) 756 WP_252579017.1 HAD family hydrolase -
  J2N86_RS08775 (J2N86_08790) - 1973696..1975594 (+) 1899 WP_252579018.1 hypothetical protein -

Sequence

Protein


Download         Length: 410 a.a.        Molecular weight: 45065.50 Da        Isoelectric Point: 9.8134

>NTDB_id=546007 J2N86_RS08760 WP_252579015.1 1970587..1971819(+) (pilC) [Legionella lytica strain PCM 2298]
MFQVKKNTNSLLTFRYTGKNVLGQKISGAIRARNLTLAKIDLRKQGITISKVAQKRNLIIFNQLNKKPSSADIALFSRQL
ATMVESGIPLMHALDIVAKGQINPHLQELINEIKHDIGAGLTLSETLMKHSQYFNSLFCNLVKAGEQSGTLDIMLNKIAC
YKEKIESIKKKIKKAVSYPIAIVSVAVIVTVGLLMFVVPQFETLFQSFGADLPTLTLAVVKISQYIQSCWYCIFSSLALS
IYAFIYAQKHSTAFAITVDKLLLKIPVIGPIIEKTVIARFSRTLSITFAAGLPLVDGLKSAAGATGNIMYANAIEYIKNE
VFTGISMNKAMENTHLFPNMVMQMIAIGEESGALEKMLSKIADFYEEDVDNSVDALSRLLEPIIMSIIGILVGGLIVAMY
MPLFKLGAVI

Nucleotide


Download         Length: 1233 bp        

>NTDB_id=546007 J2N86_RS08760 WP_252579015.1 1970587..1971819(+) (pilC) [Legionella lytica strain PCM 2298]
ATGTTTCAGGTTAAAAAAAATACCAACTCCCTATTAACATTTCGTTATACGGGTAAAAATGTATTAGGACAAAAAATCTC
AGGAGCCATTCGAGCACGTAATTTGACGCTCGCGAAAATAGACCTACGCAAGCAAGGCATTACTATTAGTAAAGTAGCTC
AAAAGCGGAATCTAATAATCTTTAATCAATTAAATAAAAAGCCAAGTTCAGCAGACATTGCGCTATTTAGCCGTCAACTT
GCCACCATGGTTGAATCAGGAATACCGTTAATGCACGCGCTTGATATTGTTGCGAAAGGACAAATAAATCCCCATCTTCA
GGAATTAATTAATGAGATCAAACATGATATTGGGGCAGGTTTAACACTGTCTGAAACATTAATGAAACATTCACAGTATT
TTAATAGCCTATTCTGTAATTTAGTTAAAGCAGGCGAACAATCAGGTACGCTAGATATTATGCTCAATAAAATTGCCTGT
TATAAAGAGAAAATTGAATCCATAAAAAAGAAAATAAAAAAAGCGGTAAGCTATCCCATCGCCATTGTAAGCGTGGCAGT
TATAGTGACAGTGGGCTTACTTATGTTTGTTGTTCCACAATTTGAAACCTTATTTCAATCATTTGGAGCCGATTTACCCA
CCCTAACTTTGGCCGTAGTTAAAATATCTCAATATATTCAATCCTGTTGGTATTGTATTTTTTCGTCTTTGGCCTTGAGC
ATTTATGCATTTATTTATGCACAAAAGCATTCTACGGCCTTCGCAATAACTGTTGATAAACTGCTATTAAAAATACCGGT
TATTGGTCCAATTATTGAAAAAACCGTTATTGCACGCTTTTCACGAACATTATCTATTACTTTTGCAGCTGGTTTGCCTT
TAGTAGATGGCCTCAAATCGGCGGCTGGTGCCACAGGCAATATAATGTATGCTAACGCAATAGAATATATAAAAAATGAG
GTTTTTACAGGAATATCCATGAATAAGGCTATGGAAAATACCCACCTATTTCCCAATATGGTCATGCAAATGATCGCTAT
TGGTGAAGAGTCAGGTGCCTTAGAAAAAATGTTAAGTAAAATTGCAGACTTTTATGAAGAAGATGTAGATAATTCAGTGG
ACGCACTGAGTCGTTTATTAGAACCGATTATCATGTCCATCATTGGGATTCTCGTGGGTGGGCTGATTGTGGCAATGTAT
ATGCCTTTGTTTAAATTGGGCGCGGTAATTTAA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(76-199)

Type II secretion system (T2SS), protein F (T2SSF)

(280-402)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilC Legionella pneumophila strain ERS1305867

66.667

98.78

0.659
  pilC Pseudomonas stutzeri DSM 10701

49.37

96.829

0.478
  pilC Acinetobacter baylyi ADP1

47.901

98.78

0.473
  pilC Acinetobacter baumannii D1279779

47.407

98.78

0.468
  pilG Neisseria gonorrhoeae MS11

40.955

97.073

0.398
  pilG Neisseria meningitidis 44/76-A

43.316

91.22

0.395
  pilC Vibrio cholerae strain A1552

38.366

98.537

0.378
  pilC Vibrio campbellii strain DS40M4

37.313

98.049

0.366