Detailed information    

insolico Bioinformatically predicted

Overview

Name   cinA   Type   Machinery gene
Locus tag   JZI44_RS00365 Genome accession   NZ_CP071148
Coordinates   64050..65321 (-) Length   423 a.a.
NCBI ID   WP_015898661.1    Uniprot ID   C0MAR7
Organism   Streptococcus equi subsp. equi strain 470_001     
Function   require for competence (predicted from homology)   
Unclear

Genomic Context

Location: 59050..70321
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  JZI44_RS00340 (JZI44_00340) - 60939..61238 (-) 300 WP_012516437.1 DUF1292 domain-containing protein -
  JZI44_RS00345 (JZI44_00345) ruvX 61248..61667 (-) 420 WP_015898660.1 Holliday junction resolvase RuvX -
  JZI44_RS00350 (JZI44_00350) - 61664..61933 (-) 270 WP_012516439.1 IreB family regulatory phosphoprotein -
  JZI44_RS00355 (JZI44_00355) spx 62046..62444 (-) 399 WP_012516440.1 transcriptional regulator Spx -
  JZI44_RS00360 (JZI44_00360) recA 62820..63956 (-) 1137 WP_012678688.1 recombinase RecA Machinery gene
  JZI44_RS00365 (JZI44_00365) cinA 64050..65321 (-) 1272 WP_015898661.1 competence/damage-inducible protein A Machinery gene
  JZI44_RS00370 (JZI44_00370) - 66007..66297 (-) 291 WP_012516443.1 hypothetical protein -
  JZI44_RS00375 (JZI44_00375) - 66291..66863 (-) 573 WP_015898662.1 phospholipase A2 SlaB -
  JZI44_RS00380 (JZI44_00380) - 67160..68005 (+) 846 WP_012678692.1 helix-turn-helix transcriptional regulator -
  JZI44_RS00385 (JZI44_00385) - 68441..68992 (-) 552 WP_015898663.1 DNA-3-methyladenine glycosylase I -
  JZI44_RS00390 (JZI44_00390) ruvA 69002..69598 (-) 597 WP_015898664.1 Holliday junction branch migration protein RuvA -

Sequence

Protein


Download         Length: 423 a.a.        Molecular weight: 45765.45 Da        Isoelectric Point: 6.1706

>NTDB_id=543209 JZI44_RS00365 WP_015898661.1 64050..65321(-) (cinA) [Streptococcus equi subsp. equi strain 470_001]
MKAELIAVGTEILTGQIVNTNAQFLSEKMAELGIDVYFQTAVGDNEERLLSVIDIASQRSDLVILCGGLGPTDDDLTKQT
LAKYLGKALVFDEQAGQKLDAFFAHRKQAARTPNNQRQAQLIEGSIALQNQTGLAVGGLITVDRVTYVVLPGPPSELKPM
VKNELVPLLSASHASLYSRVLRFFGIGESQLVTALEDLIKHQTDPTIAPYAKTGEVTLRLSTKADNQALADERLNRLEAQ
LLSIRTVDNQPLRRLLYGYGEDNSLARETFELLKRSGKTITAAESLTAGLFQAQLTDFAGASQVFNGGFITYSIEEKARM
LGIPLGELQRHGVVSSFTAEQMAAQARCLTNSDIGIGLTGVAGPEALEGQPAGTVFIGLATKNKVESLKVVIGGRSRLDV
RYIAALYAFNMVRKTLLKSENLL

Nucleotide


Download         Length: 1272 bp        

>NTDB_id=543209 JZI44_RS00365 WP_015898661.1 64050..65321(-) (cinA) [Streptococcus equi subsp. equi strain 470_001]
ATGAAAGCTGAACTCATTGCGGTGGGAACCGAGATTCTGACTGGTCAGATTGTGAATACCAATGCTCAATTTTTATCAGA
AAAAATGGCGGAGCTTGGTATTGATGTTTATTTTCAAACAGCTGTAGGAGATAATGAAGAGCGTTTGCTTTCTGTTATTG
ATATTGCTAGCCAGCGAAGTGATTTAGTGATTTTATGTGGTGGTCTTGGTCCAACAGATGATGATCTAACGAAGCAGACC
TTAGCTAAGTATCTGGGAAAAGCTTTGGTCTTTGATGAGCAGGCAGGTCAAAAATTAGATGCTTTTTTTGCACATCGTAA
GCAGGCTGCTAGGACACCAAATAACCAACGTCAGGCGCAGCTGATTGAAGGCTCTATTGCTTTGCAAAATCAAACAGGAC
TTGCAGTAGGTGGGTTAATAACTGTAGATAGGGTAACCTATGTTGTCTTACCAGGGCCTCCAAGTGAGCTAAAGCCTATG
GTAAAAAATGAGCTGGTGCCCCTTCTTTCAGCTAGTCATGCCAGTCTATATTCAAGAGTGCTGCGTTTTTTTGGCATTGG
TGAAAGTCAACTGGTGACTGCTCTGGAGGATTTGATTAAGCATCAAACAGATCCTACTATTGCTCCTTATGCAAAGACCG
GCGAGGTAACACTGCGACTATCCACAAAGGCTGACAACCAAGCATTAGCTGATGAAAGGCTGAATCGACTAGAGGCGCAG
CTCTTATCCATAAGAACTGTAGATAATCAACCCTTACGGCGTTTGCTTTATGGCTATGGGGAGGATAATTCCTTGGCGCG
TGAGACCTTTGAGCTATTGAAGCGAAGTGGTAAGACGATAACAGCAGCTGAAAGCTTAACAGCAGGACTGTTTCAAGCTC
AGTTAACTGATTTTGCGGGAGCTTCACAGGTGTTTAACGGTGGCTTTATCACCTACAGCATTGAAGAAAAAGCAAGAATG
CTTGGCATTCCATTGGGTGAGCTACAAAGGCATGGTGTTGTGAGCTCTTTTACAGCTGAGCAAATGGCTGCACAGGCACG
CTGCTTGACCAATTCAGATATCGGTATTGGTCTAACAGGTGTTGCTGGTCCAGAGGCACTCGAGGGACAGCCAGCAGGAA
CAGTTTTCATTGGCCTTGCCACTAAGAATAAGGTAGAATCTCTTAAAGTTGTTATAGGAGGCCGTAGCCGTTTGGACGTG
CGGTATATTGCTGCCCTATATGCTTTTAATATGGTTCGTAAAACTTTATTAAAATCAGAGAATTTGCTATAA

Domains

Predicted by InterproScan.

Competence-damaged protein (CinA)

(263-416)

Damage-inducible protein CinA KH domain (CinA_KH)

(178-241)

Probable molybdopterin binding domain (MoCF_biosynth)

(5-169)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB C0MAR7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cinA Streptococcus mutans UA159

70.686

100

0.707
  cinA Streptococcus mitis NCTC 12261

70.504

98.582

0.695
  cinA Streptococcus mitis SK321

70.264

98.582

0.693
  cinA Streptococcus pneumoniae TIGR4

70.024

98.582

0.69
  cinA Streptococcus pneumoniae Rx1

70.024

98.582

0.69
  cinA Streptococcus pneumoniae R6

70.024

98.582

0.69
  cinA Streptococcus pneumoniae D39

69.784

98.582

0.688
  cinA Streptococcus suis isolate S10

54.177

99.054

0.537
  cinA Bacillus subtilis subsp. subtilis str. 168

47.847

98.818

0.473