Detailed information    

insolico Bioinformatically predicted

Overview

Name   cinA   Type   Machinery gene
Locus tag   JZI48_RS05385 Genome accession   NZ_CP071145
Coordinates   1113714..1114985 (+) Length   423 a.a.
NCBI ID   WP_015898661.1    Uniprot ID   C0MAR7
Organism   Streptococcus equi subsp. equi strain 470_007     
Function   require for competence (predicted from homology)   
Unclear

Genomic Context

Location: 1108714..1119985
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  JZI48_RS05360 (JZI48_05360) ruvA 1109437..1110033 (+) 597 WP_015898664.1 Holliday junction branch migration protein RuvA -
  JZI48_RS05365 (JZI48_05365) - 1110043..1110594 (+) 552 WP_015898663.1 DNA-3-methyladenine glycosylase I -
  JZI48_RS05370 (JZI48_05370) - 1111030..1111875 (-) 846 WP_012678692.1 helix-turn-helix transcriptional regulator -
  JZI48_RS05375 (JZI48_05375) - 1112172..1112744 (+) 573 WP_015898662.1 phospholipase A2 SlaB -
  JZI48_RS05380 (JZI48_05380) - 1112738..1113028 (+) 291 WP_012516443.1 hypothetical protein -
  JZI48_RS05385 (JZI48_05385) cinA 1113714..1114985 (+) 1272 WP_015898661.1 competence/damage-inducible protein A Machinery gene
  JZI48_RS05390 (JZI48_05390) recA 1115079..1116215 (+) 1137 WP_012678688.1 recombinase RecA Machinery gene
  JZI48_RS05395 (JZI48_05395) spx 1116591..1116989 (+) 399 WP_012516440.1 transcriptional regulator Spx -
  JZI48_RS05400 (JZI48_05400) - 1117102..1117371 (+) 270 WP_012516439.1 IreB family regulatory phosphoprotein -
  JZI48_RS05405 (JZI48_05405) ruvX 1117368..1117787 (+) 420 WP_015898660.1 Holliday junction resolvase RuvX -
  JZI48_RS05410 (JZI48_05410) - 1117797..1118096 (+) 300 WP_012516437.1 DUF1292 domain-containing protein -

Sequence

Protein


Download         Length: 423 a.a.        Molecular weight: 45765.45 Da        Isoelectric Point: 6.1706

>NTDB_id=543173 JZI48_RS05385 WP_015898661.1 1113714..1114985(+) (cinA) [Streptococcus equi subsp. equi strain 470_007]
MKAELIAVGTEILTGQIVNTNAQFLSEKMAELGIDVYFQTAVGDNEERLLSVIDIASQRSDLVILCGGLGPTDDDLTKQT
LAKYLGKALVFDEQAGQKLDAFFAHRKQAARTPNNQRQAQLIEGSIALQNQTGLAVGGLITVDRVTYVVLPGPPSELKPM
VKNELVPLLSASHASLYSRVLRFFGIGESQLVTALEDLIKHQTDPTIAPYAKTGEVTLRLSTKADNQALADERLNRLEAQ
LLSIRTVDNQPLRRLLYGYGEDNSLARETFELLKRSGKTITAAESLTAGLFQAQLTDFAGASQVFNGGFITYSIEEKARM
LGIPLGELQRHGVVSSFTAEQMAAQARCLTNSDIGIGLTGVAGPEALEGQPAGTVFIGLATKNKVESLKVVIGGRSRLDV
RYIAALYAFNMVRKTLLKSENLL

Nucleotide


Download         Length: 1272 bp        

>NTDB_id=543173 JZI48_RS05385 WP_015898661.1 1113714..1114985(+) (cinA) [Streptococcus equi subsp. equi strain 470_007]
ATGAAAGCTGAACTCATTGCGGTGGGAACCGAGATTCTGACTGGTCAGATTGTGAATACCAATGCTCAATTTTTATCAGA
AAAAATGGCGGAGCTTGGTATTGATGTTTATTTTCAAACAGCTGTAGGAGATAATGAAGAGCGTTTGCTTTCTGTTATTG
ATATTGCTAGCCAGCGAAGTGATTTAGTGATTTTATGTGGTGGTCTTGGTCCAACAGATGATGATCTAACGAAGCAGACC
TTAGCTAAGTATCTGGGAAAAGCTTTGGTCTTTGATGAGCAGGCAGGTCAAAAATTAGATGCTTTTTTTGCACATCGTAA
GCAGGCTGCTAGGACACCAAATAACCAACGTCAGGCGCAGCTGATTGAAGGCTCTATTGCTTTGCAAAATCAAACAGGAC
TTGCAGTAGGTGGGTTAATAACTGTAGATAGGGTAACCTATGTTGTCTTACCAGGGCCTCCAAGTGAGCTAAAGCCTATG
GTAAAAAATGAGCTGGTGCCCCTTCTTTCAGCTAGTCATGCCAGTCTATATTCAAGAGTGCTGCGTTTTTTTGGCATTGG
TGAAAGTCAACTGGTGACTGCTCTGGAGGATTTGATTAAGCATCAAACAGATCCTACTATTGCTCCTTATGCAAAGACCG
GCGAGGTAACACTGCGACTATCCACAAAGGCTGACAACCAAGCATTAGCTGATGAAAGGCTGAATCGACTAGAGGCGCAG
CTCTTATCCATAAGAACTGTAGATAATCAACCCTTACGGCGTTTGCTTTATGGCTATGGGGAGGATAATTCCTTGGCGCG
TGAGACCTTTGAGCTATTGAAGCGAAGTGGTAAGACGATAACAGCAGCTGAAAGCTTAACAGCAGGACTGTTTCAAGCTC
AGTTAACTGATTTTGCGGGAGCTTCACAGGTGTTTAACGGTGGCTTTATCACCTACAGCATTGAAGAAAAAGCAAGAATG
CTTGGCATTCCATTGGGTGAGCTACAAAGGCATGGTGTTGTGAGCTCTTTTACAGCTGAGCAAATGGCTGCACAGGCACG
CTGCTTGACCAATTCAGATATCGGTATTGGTCTAACAGGTGTTGCTGGTCCAGAGGCACTCGAGGGACAGCCAGCAGGAA
CAGTTTTCATTGGCCTTGCCACTAAGAATAAGGTAGAATCTCTTAAAGTTGTTATAGGAGGCCGTAGCCGTTTGGACGTG
CGGTATATTGCTGCCCTATATGCTTTTAATATGGTTCGTAAAACTTTATTAAAATCAGAGAATTTGCTATAA

Domains

Predicted by InterproScan.

Competence-damaged protein (CinA)

(263-416)

Damage-inducible protein CinA KH domain (CinA_KH)

(178-241)

Probable molybdopterin binding domain (MoCF_biosynth)

(5-169)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB C0MAR7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cinA Streptococcus mutans UA159

70.686

100

0.707
  cinA Streptococcus mitis NCTC 12261

70.504

98.582

0.695
  cinA Streptococcus mitis SK321

70.264

98.582

0.693
  cinA Streptococcus pneumoniae TIGR4

70.024

98.582

0.69
  cinA Streptococcus pneumoniae Rx1

70.024

98.582

0.69
  cinA Streptococcus pneumoniae R6

70.024

98.582

0.69
  cinA Streptococcus pneumoniae D39

69.784

98.582

0.688
  cinA Streptococcus suis isolate S10

54.177

99.054

0.537
  cinA Bacillus subtilis subsp. subtilis str. 168

47.847

98.818

0.473