Detailed information NTG0541216

Bioinformatically predicted

Overview

• Name: covR
• Type: Regulator
• Locus tag: JW886_RS07205
• Genome accession: NZ_CP070872
• Coordinates: 1467438..1468130 (-)
• Length: 230 a.a.
• NCBI ID: WP_075525432.1
• Uniprot ID: -
• Organism: Lactococcus taiwanensis strain K_LL004
• Function: repress the expression of comX (predicted from homology) Competence regulation

Genomic Context

Location: 1462438..1473130

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
JW886_RS07185 (JW886_07185)	murD	1462539..1463900 (-)	1362	WP_205871705.1	UDP-N-acetylmuramoyl-L-alanine--D-glutamate ligase	-
JW886_RS07190 (JW886_07190)	-	1464086..1464427 (-)	342	WP_075525435.1	P-II family nitrogen regulator	-
JW886_RS07195 (JW886_07195)	-	1464487..1465728 (-)	1242	WP_205871706.1	ammonium transporter	-
JW886_RS07200 (JW886_07200)	covS	1465954..1467426 (-)	1473	WP_075525433.1	HAMP domain-containing sensor histidine kinase	Regulator
JW886_RS07205 (JW886_07205)	covR	1467438..1468130 (-)	693	WP_075525432.1	response regulator transcription factor	Regulator
JW886_RS07210 (JW886_07210)	-	1468290..1468820 (-)	531	WP_075525431.1	DUF177 domain-containing protein	-
JW886_RS07215 (JW886_07215)	-	1468952..1469197 (-)	246	WP_075525430.1	type B 50S ribosomal protein L31	-
JW886_RS07220 (JW886_07220)	-	1469337..1469807 (-)	471	WP_200407168.1	hypothetical protein	-
JW886_RS07225 (JW886_07225)	-	1469905..1470105 (-)	201	WP_205871707.1	hypothetical protein	-
JW886_RS07230 (JW886_07230)	-	1470421..1471629 (-)	1209	WP_205871708.1	amidohydrolase	-
JW886_RS07235 (JW886_07235)	-	1471897..1472097 (-)	201	WP_075525426.1	cold-shock protein	-
JW886_RS07240 (JW886_07240)	-	1472460..1472798 (+)	339	WP_205871709.1	DUF898 family protein	-

Sequence

Protein

• Length: 230 a.a.
• Molecular weight: 26671.40 Da
• Isoelectric Point: 5.0076

>NTDB_id=541216 JW886_RS07205 WP_075525432.1 1467438..1468130(-) (covR) [Lactococcus taiwanensis strain K_LL004]
MASKKILIIEDEKNLARFVSLELEHEGYATEIKDNGRAGLEEAISKDYDLILLDLMLPELDGFEVARRLRKEKDTPIIMM
TARDSTMDRVAGLDIGADDYITKPFAIEELLARVRAFFRREEHSQAVERAENTSFRDLVIDKTNRTVHRGKKVIDLTRRE
YDLLLTLMQNVGDVVTREHLVSQVWGYEEGTETNVVDVYIRYLRNKIDVEGQDSYIQTVRGLGYVMRERK

Nucleotide

• Length: 693 bp

>NTDB_id=541216 JW886_RS07205 WP_075525432.1 1467438..1468130(-) (covR) [Lactococcus taiwanensis strain K_LL004]
ATGGCATCAAAAAAGATTTTAATTATTGAGGACGAAAAGAATTTAGCACGCTTCGTCTCTCTTGAATTAGAGCATGAAGG
GTATGCAACGGAAATCAAAGATAATGGGCGTGCGGGACTTGAAGAAGCCATTTCTAAAGATTATGACTTGATTTTACTTG
ACCTGATGTTGCCAGAGTTGGATGGATTTGAAGTCGCTCGTCGTTTGCGTAAGGAAAAAGACACCCCAATTATCATGATG
ACAGCACGTGACTCAACTATGGACCGCGTGGCTGGTCTTGATATTGGAGCGGATGACTATATTACAAAACCTTTTGCAAT
TGAAGAACTGTTGGCGCGTGTGCGGGCTTTCTTCCGTCGAGAAGAGCATAGCCAAGCAGTAGAGCGAGCTGAAAATACTT
CTTTCCGTGATCTTGTGATTGATAAAACAAATCGTACGGTTCACCGTGGAAAAAAAGTTATAGACTTGACACGTCGCGAA
TATGATCTCCTTTTGACGCTGATGCAAAATGTTGGTGACGTAGTAACTCGTGAGCACTTGGTATCGCAAGTTTGGGGTTA
TGAAGAAGGAACGGAAACAAATGTCGTTGATGTTTATATTCGTTACCTCCGTAATAAAATTGATGTGGAAGGTCAAGATA
GTTATATTCAAACTGTGCGTGGCTTAGGATATGTAATGCGTGAGCGTAAGTAA

Domains

Predicted by InterproScan.

• Transcriptional regulatory protein, C terminal (Trans_reg_C) (153-226)

• Response regulator receiver domain (Response_reg) (6-115)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
covR	Lactococcus lactis subsp. lactis strain DGCC12653	97.826	100	0.978
covR	Streptococcus salivarius strain HSISS4	68.421	99.13	0.678
vicR	Streptococcus mutans UA159	45.887	100	0.461
micA	Streptococcus pneumoniae Cp1015	43.478	100	0.435
ciaR	Streptococcus mutans UA159	36.726	98.261	0.361
ciaR	Streptococcus pneumoniae Rx1	36.726	98.261	0.361
ciaR	Streptococcus pneumoniae D39	36.726	98.261	0.361
ciaR	Streptococcus pneumoniae R6	36.726	98.261	0.361
ciaR	Streptococcus pneumoniae TIGR4	36.726	98.261	0.361