Detailed information    

insolico Bioinformatically predicted

Overview

Name   covS   Type   Regulator
Locus tag   JW886_RS07200 Genome accession   NZ_CP070872
Coordinates   1465954..1467426 (-) Length   490 a.a.
NCBI ID   WP_075525433.1    Uniprot ID   A0AA45KHY0
Organism   Lactococcus taiwanensis strain K_LL004     
Function   repress the expression of comX (predicted from homology)   
Competence regulation

Genomic Context

Location: 1460954..1472426
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  JW886_RS07180 (JW886_07180) murG 1461327..1462400 (-) 1074 WP_075525437.1 undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase -
  JW886_RS07185 (JW886_07185) murD 1462539..1463900 (-) 1362 WP_205871705.1 UDP-N-acetylmuramoyl-L-alanine--D-glutamate ligase -
  JW886_RS07190 (JW886_07190) - 1464086..1464427 (-) 342 WP_075525435.1 P-II family nitrogen regulator -
  JW886_RS07195 (JW886_07195) - 1464487..1465728 (-) 1242 WP_205871706.1 ammonium transporter -
  JW886_RS07200 (JW886_07200) covS 1465954..1467426 (-) 1473 WP_075525433.1 HAMP domain-containing sensor histidine kinase Regulator
  JW886_RS07205 (JW886_07205) covR 1467438..1468130 (-) 693 WP_075525432.1 response regulator transcription factor Regulator
  JW886_RS07210 (JW886_07210) - 1468290..1468820 (-) 531 WP_075525431.1 DUF177 domain-containing protein -
  JW886_RS07215 (JW886_07215) - 1468952..1469197 (-) 246 WP_075525430.1 type B 50S ribosomal protein L31 -
  JW886_RS07220 (JW886_07220) - 1469337..1469807 (-) 471 WP_200407168.1 hypothetical protein -
  JW886_RS07225 (JW886_07225) - 1469905..1470105 (-) 201 WP_205871707.1 hypothetical protein -
  JW886_RS07230 (JW886_07230) - 1470421..1471629 (-) 1209 WP_205871708.1 amidohydrolase -
  JW886_RS07235 (JW886_07235) - 1471897..1472097 (-) 201 WP_075525426.1 cold-shock protein -

Sequence

Protein


Download         Length: 490 a.a.        Molecular weight: 56246.46 Da        Isoelectric Point: 5.1966

>NTDB_id=541215 JW886_RS07200 WP_075525433.1 1465954..1467426(-) (covS) [Lactococcus taiwanensis strain K_LL004]
MKKIFTFDTKKKTVKESAAKRSIMLRWAFANTVFCFITFTLFATLTYQLTISSFIREEQRILLKSMDSVDQILEESKVPL
DADNLNNFFEYTAQIQGDDTGMTLTSLVGTRKAFYIYDVNGQLLYATNRHIFEKQNLKDNEIKEVEGSHPGFLVERRIIS
KSTGKVVGYLQAFYDTTTYHRISNLLLIALLILEIVALIIAQIIGYFMANYFMKPLEKLHQGMQKMANNPKNEFEPILIT
SGDEIEELANVYNDMMQKMKDYLEQQKRFVSDVSHELRTPLAVLDGHINLLNRWGKNDPEILDESLQASLDEVQRMKKML
EEMLALARLENVDLSSSELDSDVSKVCQQAVKNFQLLHEDFEILFDNQLVYPTHARISENHYEQGLRILLDNAVKYSPDD
RKNVVIKLTEDEDYVITSVTDQGIGIAKEDIEHLFERFFRADKARNREIGGTGLGLSILARLAENYQGAVEVSSELGKGS
TFTLRFPKIM

Nucleotide


Download         Length: 1473 bp        

>NTDB_id=541215 JW886_RS07200 WP_075525433.1 1465954..1467426(-) (covS) [Lactococcus taiwanensis strain K_LL004]
ATGAAAAAAATATTCACTTTTGATACTAAAAAGAAAACGGTAAAGGAAAGCGCGGCTAAGCGAAGTATTATGCTTAGGTG
GGCTTTTGCTAATACCGTTTTTTGTTTTATCACCTTTACTTTATTTGCTACTCTGACTTATCAGCTGACCATCAGCTCAT
TCATCAGAGAAGAGCAGCGTATTTTACTGAAGTCAATGGATAGCGTAGACCAGATTTTGGAAGAGTCCAAAGTTCCTTTA
GATGCCGATAATTTAAATAATTTTTTTGAATATACGGCACAGATTCAAGGAGATGATACGGGGATGACTCTGACAAGCCT
TGTGGGAACACGCAAGGCTTTCTATATCTACGATGTTAATGGCCAGCTGTTATATGCTACAAATCGACATATTTTTGAAA
AACAAAATCTGAAGGATAATGAAATTAAAGAGGTGGAAGGTTCCCACCCAGGATTTTTGGTGGAGCGACGCATTATATCA
AAATCTACTGGTAAAGTAGTGGGTTATCTTCAGGCCTTCTATGATACAACCACCTATCACCGGATTTCTAATCTTCTTTT
GATTGCACTGCTTATTTTGGAAATCGTGGCTTTAATTATTGCGCAAATCATTGGCTATTTCATGGCGAATTATTTTATGA
AACCTCTTGAAAAACTCCATCAGGGAATGCAAAAGATGGCGAATAATCCTAAAAATGAATTCGAGCCGATTCTTATAACG
AGTGGAGACGAGATTGAGGAGTTAGCAAATGTTTATAACGATATGATGCAGAAGATGAAAGATTATCTGGAGCAACAAAA
ACGCTTCGTTTCGGATGTTTCCCATGAACTTAGAACGCCACTAGCTGTGTTAGATGGTCATATTAATTTGCTAAATCGTT
GGGGAAAAAATGATCCTGAGATCCTAGATGAGTCACTTCAAGCGAGTTTGGATGAAGTGCAACGGATGAAGAAAATGTTA
GAAGAAATGTTGGCTTTAGCACGCCTTGAAAATGTGGACTTGTCTAGCAGTGAGTTGGACAGTGATGTAAGTAAAGTTTG
TCAGCAGGCTGTGAAAAATTTTCAGTTGTTACATGAAGATTTTGAAATCTTATTTGATAATCAATTGGTTTACCCCACTC
ATGCACGAATCTCTGAAAATCATTATGAACAGGGCTTAAGAATCTTGTTGGATAATGCTGTGAAGTACTCGCCTGATGAT
CGTAAGAATGTAGTGATCAAACTTACGGAAGATGAGGACTACGTGATCACCAGCGTAACTGATCAAGGGATTGGGATTGC
CAAAGAAGATATTGAACATCTTTTTGAACGTTTCTTTAGAGCGGATAAGGCGCGCAATAGGGAGATTGGTGGTACGGGTC
TTGGCTTATCAATCTTGGCTCGCTTAGCTGAAAATTATCAAGGGGCGGTTGAAGTTTCTTCTGAACTTGGTAAGGGTTCC
ACCTTTACTTTAAGATTTCCTAAAATAATGTAA

Domains

Predicted by InterproScan.

HAMP domain (HAMP)

(207-259)

His Kinase A (phospho-acceptor) domain (HisKA)

(266-331)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(382-487)

ArlS sensor domain (ArlS_N)

(54-184)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covS Lactococcus lactis subsp. lactis strain DGCC12653

79.592

100

0.796