Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilC   Type   Machinery gene
Locus tag   M5M_RS17570 Genome accession   NC_018868
Coordinates   3940149..3941384 (-) Length   411 a.a.
NCBI ID   WP_015048857.1    Uniprot ID   K4KNH4
Organism   Simiduia agarivorans SA1 = DSM 21679     
Function   assembly of type IV pilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 3935149..3946384
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  M5M_RS17545 (M5M_17855) argJ 3936219..3937439 (+) 1221 WP_015048852.1 bifunctional glutamate N-acetyltransferase/amino-acid acetyltransferase ArgJ -
  M5M_RS17550 (M5M_17860) - 3937439..3938392 (+) 954 WP_024330114.1 Nudix family hydrolase -
  M5M_RS17555 (M5M_17865) yacG 3938414..3938614 (-) 201 WP_015048854.1 DNA gyrase inhibitor YacG -
  M5M_RS17560 (M5M_17870) coaE 3938662..3939255 (-) 594 WP_015048855.1 dephospho-CoA kinase -
  M5M_RS17565 (M5M_17875) pilD 3939252..3940076 (-) 825 WP_338057834.1 A24 family peptidase Machinery gene
  M5M_RS17570 (M5M_17880) pilC 3940149..3941384 (-) 1236 WP_015048857.1 type II secretion system F family protein Machinery gene
  M5M_RS17575 (M5M_17885) pilB 3941391..3943121 (-) 1731 WP_015048858.1 type IV-A pilus assembly ATPase PilB Machinery gene
  M5M_RS17580 (M5M_17890) - 3943458..3943898 (+) 441 WP_015048859.1 pilin -
  M5M_RS17585 (M5M_17895) - 3943993..3944706 (+) 714 WP_016389906.1 hypothetical protein -
  M5M_RS17590 (M5M_17900) - 3944869..3945609 (-) 741 WP_015048861.1 SDR family NAD(P)-dependent oxidoreductase -

Sequence

Protein


Download         Length: 411 a.a.        Molecular weight: 44498.55 Da        Isoelectric Point: 9.7054

>NTDB_id=54096 M5M_RS17570 WP_015048857.1 3940149..3941384(-) (pilC) [Simiduia agarivorans SA1 = DSM 21679]
MATAAKMKPQAKPTIFIYKGVDRKGKKISGEIDGSSAALVKAQLLKQGIKASTVRKKPKPLFGGGGKAIQPQDIAIFTRQ
MATMMRAGVPLVQSFEIVADGLENPNLRKLVLDIRENVASGNGFAKALEKHPKYFDELFCNLVESGEQSGALETMLDRIA
TYKEKTEKLKAKIKKAMTYPIAVLVVAVVVTGILLVKVVPQFAETFSSFGAELPAFTLLVLGLSEFAQEWWLMIVFGIVG
SVFALKEAVKRSEKVAYQKDRLSLKLPIVGQILYNSIVARFARTLSTTFSAGVPLIDALTSVSGAAGNALYRDAILKVRE
EVSSGIQLNTSLRAANMFPPMLIQMTAIGEESGALDEMLDKVAEFYEDAVDNMVDNLTALLEPMIMAVLGILVGGLMVAM
YLPIFQLGAVV

Nucleotide


Download         Length: 1236 bp        

>NTDB_id=54096 M5M_RS17570 WP_015048857.1 3940149..3941384(-) (pilC) [Simiduia agarivorans SA1 = DSM 21679]
ATGGCAACTGCAGCAAAAATGAAGCCCCAAGCCAAACCCACCATCTTTATTTACAAAGGTGTGGATCGGAAGGGCAAAAA
AATCAGTGGTGAAATTGATGGATCCAGTGCCGCTCTTGTCAAGGCTCAACTGTTGAAACAGGGTATCAAGGCCTCGACCG
TCAGGAAGAAGCCAAAGCCTCTATTTGGTGGTGGAGGCAAAGCAATACAACCTCAGGATATTGCTATTTTTACGCGCCAG
ATGGCAACCATGATGCGAGCGGGCGTGCCACTGGTGCAAAGCTTTGAAATCGTAGCAGACGGCCTTGAAAACCCAAATTT
GCGTAAGTTAGTACTCGATATCAGGGAAAATGTAGCATCGGGTAACGGCTTTGCAAAAGCACTTGAAAAACACCCCAAAT
ACTTCGATGAACTGTTTTGCAACCTGGTTGAATCCGGCGAACAATCTGGTGCACTTGAAACTATGCTCGATCGTATCGCC
ACCTATAAAGAAAAGACTGAAAAGCTAAAAGCAAAAATTAAAAAAGCAATGACCTACCCCATTGCTGTTTTAGTTGTAGC
CGTTGTCGTTACTGGCATATTGTTGGTAAAAGTTGTACCACAATTCGCTGAAACCTTCTCCTCGTTCGGCGCAGAATTAC
CTGCATTTACACTATTGGTATTGGGACTGTCCGAATTTGCCCAGGAATGGTGGCTGATGATTGTCTTCGGCATAGTCGGC
TCAGTATTCGCCCTCAAAGAGGCTGTTAAAAGATCCGAAAAGGTTGCCTATCAAAAAGATCGCCTGTCTTTGAAACTGCC
CATTGTCGGACAAATTTTATACAACTCTATTGTCGCGCGGTTTGCACGCACGCTATCTACTACCTTTTCTGCCGGCGTAC
CACTCATTGATGCTCTGACATCTGTATCTGGCGCCGCCGGCAATGCGCTGTACAGAGATGCAATTCTGAAAGTGAGGGAA
GAAGTATCTTCTGGTATTCAGCTCAATACTTCACTGCGCGCCGCCAATATGTTCCCGCCGATGCTAATCCAGATGACTGC
AATTGGTGAAGAATCAGGCGCACTGGACGAGATGCTTGATAAAGTTGCGGAGTTCTATGAGGATGCAGTAGATAACATGG
TAGACAACCTCACCGCACTCCTTGAGCCAATGATTATGGCGGTACTCGGTATTCTCGTAGGCGGTTTGATGGTTGCTATG
TACCTACCGATTTTCCAGCTTGGCGCCGTTGTTTAA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(77-200)

Type II secretion system (T2SS), protein F (T2SSF)

(281-403)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB K4KNH4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilC Pseudomonas stutzeri DSM 10701

67

97.324

0.652
  pilC Acinetobacter baylyi ADP1

60.294

99.27

0.599
  pilC Acinetobacter baumannii D1279779

59.259

98.54

0.584
  pilC Legionella pneumophila strain ERS1305867

54.04

96.35

0.521
  pilG Neisseria meningitidis 44/76-A

41.562

96.594

0.401
  pilG Neisseria gonorrhoeae MS11

41.31

96.594

0.399
  pilC Vibrio cholerae strain A1552

40.909

96.35

0.394
  pilC Vibrio campbellii strain DS40M4

39.95

98.054

0.392
  pilC Thermus thermophilus HB27

36.919

99.513

0.367

Multiple sequence alignment