Detailed information NTG0540331

Bioinformatically predicted

Overview

• Name: hexA
• Type: Machinery gene
• Locus tag: LL046_RS12105
• Genome accession: NZ_CP086088
• Coordinates: 2354483..2357005 (-)
• Length: 840 a.a.
• NCBI ID: WP_098403553.1
• Uniprot ID: -
• Organism: Lactococcus lactis subsp. lactis strain EIP13A
• Function: DNA mismatch repair (predicted from homology) Homologous recombination

Genomic Context

Location: 2349483..2362005

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
LL046_RS12085 (LL046_12035)	ruvB	2349740..2350741 (-)	1002	WP_003131994.1	Holliday junction branch migration DNA helicase RuvB	Machinery gene
LL046_RS12090 (LL046_12040)	ruvA	2350868..2351461 (-)	594	WP_017865241.1	Holliday junction branch migration protein RuvA	Machinery gene
LL046_RS12095 (LL046_12045)	hexB	2351574..2353544 (-)	1971	WP_026138979.1	DNA mismatch repair endonuclease MutL	Machinery gene
LL046_RS12100 (LL046_12050)	-	2353673..2354368 (-)	696	WP_017865243.1	hypothetical protein	-
LL046_RS12105 (LL046_12055)	hexA	2354483..2357005 (-)	2523	WP_098403553.1	DNA mismatch repair protein MutS	Machinery gene
LL046_RS12110 (LL046_12060)	-	2357198..2357545 (-)	348	WP_012898702.1	RicAFT regulatory complex protein RicA family protein	-
LL046_RS12115 (LL046_12065)	-	2357762..2358643 (-)	882	WP_003132001.1	NAD(P)-dependent oxidoreductase	-
LL046_RS12120 (LL046_12070)	-	2358685..2358891 (-)	207	WP_211752759.1	hypothetical protein	-
LL046_RS12130 (LL046_12080)	-	2359186..2359563 (-)	378	WP_017865245.1	DUF1634 domain-containing protein	-
LL046_RS12135 (LL046_12085)	-	2359563..2360414 (-)	852	WP_010906392.1	sulfite exporter TauE/SafE family protein	-
LL046_RS12140 (LL046_12090)	-	2360600..2360779 (+)	180	WP_003132007.1	hypothetical protein	-

Sequence

Protein

• Length: 840 a.a.
• Molecular weight: 94195.17 Da
• Isoelectric Point: 4.7017

>NTDB_id=540331 LL046_RS12105 WP_098403553.1 2354483..2357005(-) (hexA) [Lactococcus lactis subsp. lactis strain EIP13A]
MAEKISPGMQQYLDIKQDYPDAFLLFRMGDFYELFYDDAVNAAQILELTLTSRNKNSENPIPMAGVPHHAAAEYIDKLVD
LGYKVAVAEQMEDPKKAVGIVKRAVTQVITPGTTIDTANSVDNNFLVAIDFKDKHYALSYMDLSTGEFKVTELSEFSAVV
GEIASLKAREIVAGFTLDESQLKVFERQMNLLISEQIEIPENLLIDLSGLTALENQVASKLLAYVKETQMRDLSHLQEVE
HYEIKDFLQMDFATKSSLELTANKRENKKHGTLYWLLDETKTAMGTRMLRSWIDRPLVSNSAIQKRMEIVQIFLDHFFER
SDLIEALKGVYDLERLASRVSFGKAVPVDFLQLANSLSNVPAIKNILGMLNEAPLEELKSQLDEIPELSGLINSAISENA
SRTITEGGIIKKGYNAQLDKYREALENGTSWIGKLEADEKAKTGISTLRIDYNRKDGYYFHITQSQLNSVPEHFYRKATL
KNSERFGSQELTEIEEIMLEAREKSSSLEYDLFMGLRTETEQYIGRLQALAKTIAEIDCLQSLSVVAEKKGYIRPTLTDG
SRIVEIKGGRHAVVEAVMGAQEYVPNDIELPEQTDIQLITGPNMSGKSTYMRQFALTVIMAQIGSFVPAETANLPIFDAI
FTRIGASDNLISGESTFMVEMSEANHAIQKASSRSLIIFDELGRGTATYDGMALAQAIIEYVHDHIGAKTLFATHYHELT
DLDEALDHLDNVHVATLEQNGNVTFLHKITEGPADKSYGIHVAKIAGLPQPLLERADLILQKLENKPLPAKKVADEQEQL
SLFDFTENSSEIIEKIKRQNVDNMTAREALNFLWELKDSL

Nucleotide

• Length: 2523 bp

>NTDB_id=540331 LL046_RS12105 WP_098403553.1 2354483..2357005(-) (hexA) [Lactococcus lactis subsp. lactis strain EIP13A]
ATGGCTGAAAAAATTTCACCAGGAATGCAACAATATTTAGACATCAAACAAGATTATCCCGATGCTTTCTTGCTCTTTCG
GATGGGTGATTTTTATGAGCTTTTCTATGATGATGCAGTGAATGCTGCCCAAATATTAGAATTAACCCTGACTTCAAGAA
ATAAAAATTCAGAAAATCCAATTCCAATGGCTGGTGTTCCCCACCATGCAGCAGCTGAATACATTGATAAATTGGTTGAT
TTAGGCTACAAAGTGGCTGTTGCTGAACAAATGGAAGACCCGAAAAAAGCGGTCGGAATTGTTAAACGGGCAGTAACACA
GGTGATTACCCCAGGGACAACGATTGACACTGCAAATTCGGTTGATAATAATTTCTTGGTGGCAATTGACTTCAAAGATA
AACATTATGCTCTTTCCTATATGGACTTATCAACTGGGGAATTCAAGGTGACAGAGCTCAGCGAATTTTCAGCGGTGGTG
GGAGAAATTGCTTCACTCAAGGCGCGGGAAATTGTAGCTGGTTTTACTTTAGATGAAAGTCAATTAAAAGTTTTTGAAAG
ACAAATGAATCTTTTGATTTCAGAACAAATTGAAATTCCTGAAAATTTACTGATAGATTTGTCAGGATTGACCGCCCTAG
AAAATCAAGTCGCTTCAAAATTGTTGGCTTACGTAAAAGAAACACAAATGCGTGATTTGAGTCACTTACAAGAAGTTGAA
CATTATGAAATTAAAGACTTTTTGCAAATGGACTTTGCGACAAAATCATCTTTAGAGCTGACGGCAAATAAAAGAGAAAA
TAAAAAACATGGCACACTTTATTGGTTGCTTGATGAGACGAAAACAGCGATGGGAACCAGAATGTTACGGTCGTGGATTG
ACCGTCCTTTGGTTTCAAATTCAGCCATTCAAAAACGAATGGAAATTGTTCAAATTTTCTTAGACCATTTCTTTGAGCGT
TCCGATTTGATAGAAGCCTTAAAAGGGGTCTATGATTTAGAACGTTTGGCTTCACGTGTTTCTTTTGGTAAGGCTGTTCC
GGTTGATTTTTTGCAGCTGGCTAATTCTTTATCAAATGTTCCTGCTATCAAAAATATTTTGGGAATGCTTAATGAAGCTC
CATTAGAAGAGTTAAAAAGCCAATTAGACGAAATTCCAGAATTATCTGGTTTAATTAATTCAGCTATTAGTGAGAATGCC
TCAAGAACGATTACTGAAGGGGGCATTATTAAAAAAGGCTACAATGCTCAATTAGATAAATATCGGGAGGCGCTTGAAAA
TGGGACTTCTTGGATTGGAAAATTGGAAGCAGATGAAAAAGCCAAGACAGGAATTTCCACACTACGAATTGATTATAATC
GTAAGGATGGTTATTATTTTCATATTACTCAAAGTCAGTTGAATAGTGTTCCTGAACATTTTTATCGGAAGGCAACTTTG
AAAAATTCTGAGCGTTTTGGTTCTCAGGAATTAACTGAAATTGAAGAAATTATGTTGGAAGCGCGTGAAAAATCATCATC
TCTAGAATATGATTTATTCATGGGCCTTCGGACTGAAACGGAGCAATATATTGGCAGACTACAAGCTCTAGCCAAAACAA
TTGCTGAAATTGATTGTTTACAAAGTCTATCTGTCGTTGCCGAAAAAAAAGGATATATCCGTCCGACGCTTACAGACGGT
TCAAGAATTGTTGAAATTAAAGGCGGTCGTCATGCGGTCGTTGAAGCGGTCATGGGTGCTCAAGAATATGTGCCAAATGA
TATTGAACTGCCTGAACAAACAGATATTCAACTCATCACAGGACCGAATATGTCAGGTAAATCAACCTACATGCGTCAAT
TTGCTTTGACGGTGATTATGGCTCAAATTGGATCTTTTGTTCCAGCCGAAACAGCCAATTTACCAATTTTTGATGCCATC
TTTACACGGATTGGTGCCAGTGATAACTTGATTTCAGGGGAATCGACCTTTATGGTTGAAATGTCTGAGGCCAATCATGC
CATTCAAAAGGCAAGCAGTCGCAGCCTGATTATTTTTGATGAATTAGGGCGAGGAACGGCAACTTATGATGGGATGGCTC
TAGCTCAAGCAATTATTGAATATGTTCATGACCATATTGGGGCAAAGACCTTGTTTGCTACGCATTATCATGAATTGACA
GACTTAGATGAAGCGCTCGATCATCTTGATAATGTCCATGTTGCTACCTTGGAGCAAAATGGGAATGTGACTTTTTTGCA
TAAAATAACAGAGGGGCCAGCTGATAAATCCTATGGGATTCATGTGGCGAAAATTGCAGGTTTACCACAGCCTTTGTTAG
AGCGAGCAGATTTGATTTTGCAGAAGTTAGAAAATAAACCTTTGCCTGCTAAAAAAGTTGCTGATGAACAAGAACAACTT
AGTTTATTTGATTTTACCGAAAATTCTTCAGAAATTATTGAAAAGATAAAAAGGCAAAATGTTGATAATATGACTGCAAG
AGAGGCATTAAATTTCTTGTGGGAACTTAAAGATTCACTTTGA

Domains

Predicted by InterProScan.

• MutS domain II (MutS_II) (124-237)

• MutS domain I (MutS_I) (7-116)

• MutS family domain IV (MutS_IV) (413-503)

• MutS domain III (MutS_III) (254-544)

• MutS domain V (MutS_V) (598-784)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
hexA	Streptococcus pneumoniae R6	64.218	100	0.645
mutS	Pseudomonas stutzeri strain ATCC 17587	37.806	100	0.386