Detailed information NTG0540322

Bioinformatically predicted

Overview

• Name: comGA
• Type: Machinery gene
• Locus tag: LL046_RS11655
• Genome accession: NZ_CP086088
• Coordinates: 2256062..2257000 (-)
• Length: 312 a.a.
• NCBI ID: WP_211752889.1
• Uniprot ID: -
• Organism: Lactococcus lactis subsp. lactis strain EIP13A
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 2251062..2262000

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
LL046_RS11620	-	2251201..2251326 (-)	126	WP_259743439.1	hypothetical protein	-
LL046_RS11625 (LL046_11575)	-	2251372..2251593 (-)	222	WP_172758712.1	helix-turn-helix transcriptional regulator	-
LL046_RS11630 (LL046_11580)	-	2251749..2252171 (+)	423	WP_240819228.1	helix-turn-helix transcriptional regulator	-
LL046_RS11635 (LL046_11585)	-	2252182..2252766 (+)	585	WP_014570821.1	hypothetical protein	-
LL046_RS11640 (LL046_11590)	-	2252822..2253361 (+)	540	WP_023189015.1	PH domain-containing protein	-
LL046_RS11645 (LL046_11595)	-	2253487..2254944 (+)	1458	WP_240819271.1	recombinase family protein	-
LL046_RS11650 (LL046_11600)	comGB	2255095..2256168 (-)	1074	WP_098403501.1	competence type IV pilus assembly protein ComGB	Machinery gene
LL046_RS11655 (LL046_11605)	comGA	2256062..2257000 (-)	939	WP_211752889.1	competence type IV pilus ATPase ComGA	Machinery gene

Sequence

Protein

• Length: 312 a.a.
• Molecular weight: 35656.91 Da
• Isoelectric Point: 5.9445

>NTDB_id=540322 LL046_RS11655 WP_211752889.1 2256062..2257000(-) (comGA) [Lactococcus lactis subsp. lactis strain EIP13A]
MIPKMAKELIQRAIDRDASDIYLIASKEKYKLYFRQMTARVLVEEIGLEVGLALLTHFKFLAGMNTGERRRVQMGACWYE
LEESNAKRLRLSTVGDFEGNESLVIRLLHDQNKELDFWFDEELENYDCKRGLHLFAGPVGSGKTSLMFDLARRHFTDLQV
ITIEEPVELIDSDFIQLQVNEVIGNSYDELIKLSLRHRPDLLIVGEIRDKLTAQAVLRASLTGYTVFSTVHASSVRGVIQ
RLSELGLSHWEIKNALSSVVYQCLIAGKGVLDIAKNEFESWSSENWNKKIDQLLTNGYLTPTEAKREKIKTD

Nucleotide

• Length: 939 bp

>NTDB_id=540322 LL046_RS11655 WP_211752889.1 2256062..2257000(-) (comGA) [Lactococcus lactis subsp. lactis strain EIP13A]
ATGATACCAAAAATGGCAAAAGAATTAATTCAAAGAGCAATTGATAGAGATGCATCAGATATTTATCTGATTGCTTCAAA
AGAAAAGTATAAACTTTATTTTCGACAAATGACAGCGCGTGTTCTGGTAGAAGAAATTGGGTTAGAAGTTGGCTTAGCAC
TACTTACTCACTTTAAGTTTCTAGCTGGGATGAATACAGGAGAACGCAGACGAGTTCAAATGGGAGCTTGTTGGTATGAA
TTAGAGGAAAGTAATGCAAAACGTTTGCGTCTTTCAACAGTGGGGGATTTCGAGGGTAATGAATCCTTAGTAATACGTCT
CTTGCATGATCAAAACAAAGAACTTGATTTTTGGTTTGATGAAGAGCTAGAGAATTATGATTGTAAAAGAGGATTGCATC
TCTTTGCCGGTCCAGTAGGCTCGGGAAAAACATCTTTAATGTTTGATTTAGCTCGTCGTCATTTTACAGATTTACAAGTT
ATCACTATTGAAGAACCCGTTGAGTTGATTGATTCCGATTTTATTCAGTTACAAGTCAACGAAGTCATTGGTAATAGTTA
TGATGAATTAATTAAATTATCACTGAGGCATCGCCCAGATTTGTTAATCGTTGGTGAAATTCGTGATAAATTGACCGCTC
AAGCAGTTTTACGGGCTAGTTTGACAGGTTATACAGTGTTTTCAACCGTTCATGCCTCTTCTGTTAGAGGTGTCATTCAG
AGATTATCAGAGCTGGGTTTAAGTCATTGGGAAATAAAAAATGCTTTATCAAGTGTTGTTTATCAGTGTTTAATAGCTGG
GAAAGGAGTATTAGACATTGCCAAAAACGAATTTGAGTCTTGGTCATCAGAAAATTGGAATAAAAAAATTGATCAGCTAC
TTACAAATGGATATCTCACACCTACTGAAGCCAAAAGGGAAAAAATTAAGACTGATTAA

Domains

Predicted by InterProScan.

• Type II/IV secretion system protein (T2SSE) (9-262)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comGA	Lactococcus lactis subsp. cremoris KW2	76.603	100	0.766
comGA/cglA	Streptococcus sobrinus strain NIDR 6715-7	54.341	99.679	0.542
comGA/cglA/cilD	Streptococcus mitis NCTC 12261	52.733	99.679	0.526
comGA	Streptococcus mutans UA159	51.603	100	0.516
comGA	Streptococcus mutans UA140	51.603	100	0.516
comGA/cglA/cilD	Streptococcus pneumoniae R6	51.768	99.679	0.516
comGA/cglA/cilD	Streptococcus pneumoniae Rx1	51.768	99.679	0.516
comGA/cglA/cilD	Streptococcus pneumoniae D39	51.768	99.679	0.516
comGA/cglA/cilD	Streptococcus pneumoniae TIGR4	51.768	99.679	0.516
comGA	Streptococcus gordonii str. Challis substr. CH1	51.118	100	0.513