Detailed information NTG0539536

Bioinformatically predicted

Overview

• Name: covR
• Type: Regulator
• Locus tag: JVB21_RS01140
• Genome accession: NZ_CP070381
• Coordinates: 247578..248270 (+)
• Length: 230 a.a.
• NCBI ID: WP_075525432.1
• Uniprot ID: -
• Organism: Lactococcus taiwanensis strain K_LL001
• Function: repress the expression of comX (predicted from homology) Competence regulation

Genomic Context

Location: 242578..253270

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
JVB21_RS01105 (JVB21_01105)	-	242911..243249 (-)	339	WP_205272176.1	DUF898 family protein	-
JVB21_RS01110 (JVB21_01110)	-	243611..243811 (+)	201	WP_075525426.1	cold-shock protein	-
JVB21_RS01115 (JVB21_01115)	-	244079..245287 (+)	1209	WP_205272177.1	amidohydrolase	-
JVB21_RS01120 (JVB21_01120)	-	245570..245803 (+)	234	WP_205272178.1	hypothetical protein	-
JVB21_RS01125 (JVB21_01125)	-	245925..246371 (+)	447	WP_240188625.1	hypothetical protein	-
JVB21_RS01130 (JVB21_01130)	-	246511..246756 (+)	246	WP_075525430.1	type B 50S ribosomal protein L31	-
JVB21_RS01135 (JVB21_01135)	-	246888..247418 (+)	531	WP_205272179.1	YceD family protein	-
JVB21_RS01140 (JVB21_01140)	covR	247578..248270 (+)	693	WP_075525432.1	response regulator transcription factor	Regulator
JVB21_RS01145 (JVB21_01145)	covS	248282..249754 (+)	1473	WP_075525433.1	HAMP domain-containing sensor histidine kinase	Regulator
JVB21_RS01150 (JVB21_01150)	-	249979..251220 (+)	1242	WP_205272180.1	ammonium transporter	-
JVB21_RS01155 (JVB21_01155)	-	251280..251621 (+)	342	WP_205272181.1	P-II family nitrogen regulator	-
JVB21_RS01160 (JVB21_01160)	murD	251807..253168 (+)	1362	WP_205272182.1	UDP-N-acetylmuramoyl-L-alanine--D-glutamate ligase	-

Sequence

Protein

• Length: 230 a.a.
• Molecular weight: 26671.40 Da
• Isoelectric Point: 5.0076

>NTDB_id=539536 JVB21_RS01140 WP_075525432.1 247578..248270(+) (covR) [Lactococcus taiwanensis strain K_LL001]
MASKKILIIEDEKNLARFVSLELEHEGYATEIKDNGRAGLEEAISKDYDLILLDLMLPELDGFEVARRLRKEKDTPIIMM
TARDSTMDRVAGLDIGADDYITKPFAIEELLARVRAFFRREEHSQAVERAENTSFRDLVIDKTNRTVHRGKKVIDLTRRE
YDLLLTLMQNVGDVVTREHLVSQVWGYEEGTETNVVDVYIRYLRNKIDVEGQDSYIQTVRGLGYVMRERK

Nucleotide

• Length: 693 bp

>NTDB_id=539536 JVB21_RS01140 WP_075525432.1 247578..248270(+) (covR) [Lactococcus taiwanensis strain K_LL001]
ATGGCATCAAAAAAGATTTTAATTATTGAGGACGAAAAGAATTTAGCACGCTTCGTCTCTCTTGAATTAGAGCATGAAGG
GTATGCAACGGAAATCAAAGATAATGGGCGTGCGGGACTTGAAGAAGCCATTTCTAAAGATTATGACTTGATTTTACTTG
ACCTGATGTTGCCAGAGTTGGATGGATTTGAAGTCGCTCGTCGTTTGCGTAAGGAAAAAGACACCCCAATTATCATGATG
ACAGCGCGTGACTCAACTATGGACCGCGTGGCTGGTCTTGATATTGGAGCGGATGACTATATTACAAAACCTTTTGCAAT
TGAAGAACTGTTGGCGCGTGTGCGGGCTTTCTTCCGTCGAGAAGAGCATAGCCAAGCAGTAGAGCGAGCTGAAAATACTT
CTTTCCGTGATCTTGTGATTGATAAAACAAATCGTACGGTTCACCGTGGAAAAAAAGTTATAGACTTGACACGTCGCGAA
TATGATCTCCTTTTGACGCTGATGCAAAATGTTGGTGACGTAGTAACTCGTGAGCACTTGGTGTCGCAAGTTTGGGGTTA
TGAAGAAGGAACGGAGACAAATGTCGTTGATGTTTATATTCGTTACCTCCGTAATAAAATTGATGTGGAAGGTCAAGATA
GTTATATTCAAACTGTGCGTGGCTTAGGATATGTAATGCGTGAGCGTAAGTAA

Domains

Predicted by InterproScan.

• Transcriptional regulatory protein, C terminal (Trans_reg_C) (153-226)

• Response regulator receiver domain (Response_reg) (6-115)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
covR	Lactococcus lactis subsp. lactis strain DGCC12653	97.826	100	0.978
covR	Streptococcus salivarius strain HSISS4	68.421	99.13	0.678
vicR	Streptococcus mutans UA159	45.887	100	0.461
micA	Streptococcus pneumoniae Cp1015	43.478	100	0.435
ciaR	Streptococcus mutans UA159	36.726	98.261	0.361
ciaR	Streptococcus pneumoniae Rx1	36.726	98.261	0.361
ciaR	Streptococcus pneumoniae D39	36.726	98.261	0.361
ciaR	Streptococcus pneumoniae R6	36.726	98.261	0.361
ciaR	Streptococcus pneumoniae TIGR4	36.726	98.261	0.361