Detailed information    

insolico Bioinformatically predicted

Overview

Name   covS   Type   Regulator
Locus tag   JVB21_RS01145 Genome accession   NZ_CP070381
Coordinates   248282..249754 (+) Length   490 a.a.
NCBI ID   WP_075525433.1    Uniprot ID   A0AA45KHY0
Organism   Lactococcus taiwanensis strain K_LL001     
Function   repress the expression of comX (predicted from homology)   
Competence regulation

Genomic Context

Location: 243282..254754
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  JVB21_RS01110 (JVB21_01110) - 243611..243811 (+) 201 WP_075525426.1 cold-shock protein -
  JVB21_RS01115 (JVB21_01115) - 244079..245287 (+) 1209 WP_205272177.1 amidohydrolase -
  JVB21_RS01120 (JVB21_01120) - 245570..245803 (+) 234 WP_205272178.1 hypothetical protein -
  JVB21_RS01125 (JVB21_01125) - 245925..246371 (+) 447 WP_240188625.1 hypothetical protein -
  JVB21_RS01130 (JVB21_01130) - 246511..246756 (+) 246 WP_075525430.1 type B 50S ribosomal protein L31 -
  JVB21_RS01135 (JVB21_01135) - 246888..247418 (+) 531 WP_205272179.1 YceD family protein -
  JVB21_RS01140 (JVB21_01140) covR 247578..248270 (+) 693 WP_075525432.1 response regulator transcription factor Regulator
  JVB21_RS01145 (JVB21_01145) covS 248282..249754 (+) 1473 WP_075525433.1 HAMP domain-containing sensor histidine kinase Regulator
  JVB21_RS01150 (JVB21_01150) - 249979..251220 (+) 1242 WP_205272180.1 ammonium transporter -
  JVB21_RS01155 (JVB21_01155) - 251280..251621 (+) 342 WP_205272181.1 P-II family nitrogen regulator -
  JVB21_RS01160 (JVB21_01160) murD 251807..253168 (+) 1362 WP_205272182.1 UDP-N-acetylmuramoyl-L-alanine--D-glutamate ligase -
  JVB21_RS01165 (JVB21_01165) murG 253307..254380 (+) 1074 WP_205272183.1 undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase -

Sequence

Protein


Download         Length: 490 a.a.        Molecular weight: 56246.46 Da        Isoelectric Point: 5.1966

>NTDB_id=539537 JVB21_RS01145 WP_075525433.1 248282..249754(+) (covS) [Lactococcus taiwanensis strain K_LL001]
MKKIFTFDTKKKTVKESAAKRSIMLRWAFANTVFCFITFTLFATLTYQLTISSFIREEQRILLKSMDSVDQILEESKVPL
DADNLNNFFEYTAQIQGDDTGMTLTSLVGTRKAFYIYDVNGQLLYATNRHIFEKQNLKDNEIKEVEGSHPGFLVERRIIS
KSTGKVVGYLQAFYDTTTYHRISNLLLIALLILEIVALIIAQIIGYFMANYFMKPLEKLHQGMQKMANNPKNEFEPILIT
SGDEIEELANVYNDMMQKMKDYLEQQKRFVSDVSHELRTPLAVLDGHINLLNRWGKNDPEILDESLQASLDEVQRMKKML
EEMLALARLENVDLSSSELDSDVSKVCQQAVKNFQLLHEDFEILFDNQLVYPTHARISENHYEQGLRILLDNAVKYSPDD
RKNVVIKLTEDEDYVITSVTDQGIGIAKEDIEHLFERFFRADKARNREIGGTGLGLSILARLAENYQGAVEVSSELGKGS
TFTLRFPKIM

Nucleotide


Download         Length: 1473 bp        

>NTDB_id=539537 JVB21_RS01145 WP_075525433.1 248282..249754(+) (covS) [Lactococcus taiwanensis strain K_LL001]
ATGAAAAAAATATTCACTTTTGATACTAAAAAGAAAACGGTAAAGGAAAGCGCGGCTAAGCGAAGTATTATGCTTAGGTG
GGCTTTTGCTAATACCGTTTTTTGTTTTATCACCTTTACTTTATTTGCTACTCTGACTTATCAGCTGACCATCAGCTCAT
TTATCAGAGAAGAGCAGCGTATTTTGCTGAAGTCAATGGATAGCGTAGACCAGATTTTGGAAGAGTCCAAAGTTCCTTTA
GATGCCGATAATTTAAATAATTTTTTTGAATATACGGCACAGATTCAAGGAGATGATACGGGCATGACTCTGACAAGTCT
TGTGGGAACACGCAAGGCTTTCTATATCTACGATGTTAATGGCCAGCTGTTATATGCTACAAATCGGCATATTTTTGAAA
AACAAAATCTGAAAGATAATGAAATTAAAGAGGTGGAAGGTTCCCACCCAGGATTTTTGGTGGAGCGGCGCATTATATCA
AAATCTACTGGTAAAGTAGTGGGTTATCTTCAGGCCTTCTATGATACAACTACCTATCATCGGATTTCTAATCTTCTTTT
GATTGCACTGCTTATTTTGGAAATCGTGGCTTTAATTATTGCGCAAATCATTGGCTATTTCATGGCGAATTATTTTATGA
AACCTCTTGAAAAACTCCATCAGGGAATGCAAAAGATGGCGAATAATCCTAAAAATGAATTCGAGCCGATTCTTATAACG
AGTGGAGACGAGATTGAGGAGTTAGCAAATGTTTATAACGATATGATGCAGAAGATGAAAGATTATCTGGAGCAACAAAA
ACGCTTCGTTTCGGATGTTTCCCATGAACTTAGAACGCCATTAGCTGTGTTAGATGGTCATATTAATTTGCTAAATCGTT
GGGGAAAAAATGATCCTGAGATCCTAGATGAGTCACTTCAAGCGAGTTTGGATGAAGTGCAACGGATGAAGAAAATGTTA
GAAGAAATGTTGGCTTTAGCACGTCTTGAAAATGTGGATTTGTCTAGCAGTGAGTTGGATAGTGATGTAAGTAAAGTTTG
TCAGCAGGCTGTGAAAAATTTTCAGTTGTTACATGAAGATTTTGAAATTTTATTTGATAATCAATTGGTTTACCCCACTC
ATGCACGAATCTCTGAAAATCATTATGAACAGGGCTTAAGAATCTTGTTGGATAATGCTGTGAAGTACTCGCCTGATGAT
CGTAAGAATGTAGTAATCAAACTTACGGAAGATGAGGACTACGTGATCACCAGCGTAACTGATCAAGGGATTGGCATTGC
CAAAGAAGATATTGAACATCTTTTTGAACGTTTCTTTAGAGCGGATAAGGCGCGCAATAGGGAGATTGGTGGTACGGGTC
TTGGCTTATCAATCTTGGCTCGCTTAGCTGAAAATTATCAAGGGGCGGTTGAAGTTTCTTCTGAACTTGGTAAGGGTTCC
ACCTTTACTTTAAGATTTCCTAAAATAATGTAA

Domains

Predicted by InterproScan.

HAMP domain (HAMP)

(207-259)

His Kinase A (phospho-acceptor) domain (HisKA)

(266-331)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(382-487)

ArlS sensor domain (ArlS_N)

(54-184)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covS Lactococcus lactis subsp. lactis strain DGCC12653

79.592

100

0.796