Detailed information NTG0537235

Bioinformatically predicted

Overview

• Name: comEA/celA/cilE
• Type: Machinery gene
• Locus tag: I6K87_RS03125
• Genome accession: NZ_CP069892
• Coordinates: 634342..635046 (-)
• Length: 234 a.a.
• NCBI ID: WP_204982754.1
• Uniprot ID: -
• Organism: Streptococcus anginosus strain FDAARGOS_1357
• Function: dsDNA binding to the cell surface (predicted from homology) DNA binding and uptake

Genomic Context

Location: 629342..640046

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
I6K87_RS03105 (I6K87_03105)	-	629821..630807 (-)	987	WP_204982752.1	Gfo/Idh/MocA family protein	-
I6K87_RS03110 (I6K87_03110)	-	631050..631208 (+)	159	WP_003042740.1	hypothetical protein	-
I6K87_RS03115 (I6K87_03115)	-	631351..632049 (-)	699	WP_003029857.1	DUF805 domain-containing protein	-
I6K87_RS03120 (I6K87_03120)	comEC/celB	632130..634358 (-)	2229	WP_204982753.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
I6K87_RS03125 (I6K87_03125)	comEA/celA/cilE	634342..635046 (-)	705	WP_204982754.1	helix-hairpin-helix domain-containing protein	Machinery gene
I6K87_RS03130 (I6K87_03130)	smpB	635228..635695 (-)	468	WP_022526922.1	SsrA-binding protein SmpB	-
I6K87_RS03135 (I6K87_03135)	rnr	635658..637991 (-)	2334	WP_204982755.1	ribonuclease R	-
I6K87_RS03140 (I6K87_03140)	secG	638083..638316 (-)	234	WP_003024744.1	preprotein translocase subunit SecG	-
I6K87_RS03145 (I6K87_03145)	rpmG	638356..638505 (-)	150	WP_003024746.1	50S ribosomal protein L33	-
I6K87_RS03150 (I6K87_03150)	-	638489..639694 (-)	1206	WP_080977797.1	multidrug efflux MFS transporter	-

Sequence

Protein

• Length: 234 a.a.
• Molecular weight: 25054.04 Da
• Isoelectric Point: 4.8839

>NTDB_id=537235 I6K87_RS03125 WP_204982754.1 634342..635046(-) (comEA/celA/cilE) [Streptococcus anginosus strain FDAARGOS_1357]
MLETIIEKMKEYKILIGFSLIGLIIAGFLMINSKSDRQSNVAELAQETVASSKTESEEISTGTKKNSQKEKAEPQTSSSE
ESEFLTVDVKGAVKNPGIYQLKKTSRINDAIQKAGGLTTDADSKSINLAQKLTDEAVVYVATMGENAASVSSNTGQSSTS
GTSEVASQKGNKVNLNTADLSELQTISGIGQKRAQDILDYREANGKFNSVDDLKNVSGVGAKTLEKLKEYVTVD

Nucleotide

• Length: 705 bp

>NTDB_id=537235 I6K87_RS03125 WP_204982754.1 634342..635046(-) (comEA/celA/cilE) [Streptococcus anginosus strain FDAARGOS_1357]
ATGTTAGAGACAATCATTGAAAAGATGAAAGAGTACAAAATTTTGATTGGTTTCAGTTTGATTGGTTTGATAATAGCAGG
ATTTTTAATGATAAATAGTAAATCTGATAGACAATCAAATGTAGCAGAGTTAGCGCAGGAAACAGTTGCGAGTTCGAAAA
CAGAATCAGAAGAAATTTCAACTGGAACGAAGAAAAACTCACAGAAAGAAAAAGCAGAGCCTCAAACGAGTTCAAGTGAA
GAATCAGAATTTTTAACCGTAGATGTCAAGGGTGCAGTCAAAAATCCAGGTATTTATCAACTGAAAAAGACTAGCCGTAT
CAATGATGCGATTCAAAAAGCAGGTGGTTTAACGACAGACGCTGACAGCAAGTCTATCAATTTGGCGCAGAAACTAACGG
ATGAAGCTGTTGTTTATGTGGCAACTATGGGTGAGAATGCGGCGAGTGTTTCAAGCAATACAGGACAATCTTCAACATCA
GGAACTAGTGAAGTCGCATCGCAAAAAGGGAATAAGGTCAATCTAAATACAGCTGATTTATCTGAGTTGCAGACCATTTC
TGGTATTGGTCAAAAACGCGCGCAAGATATTTTAGATTATCGGGAGGCAAACGGGAAATTTAATTCCGTTGATGACCTGA
AAAATGTATCAGGAGTAGGTGCTAAAACACTAGAGAAATTGAAAGAATATGTCACAGTGGATTAA

Domains

Predicted by InterproScan.

• SLBB domain (SLBB) (87-140)

• Helix-hairpin-helix motif (HHH_3) (169-232)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comEA/celA/cilE	Streptococcus pneumoniae TIGR4	53.617	100	0.538
comEA/celA/cilE	Streptococcus pneumoniae D39	53.191	100	0.534
comEA/celA/cilE	Streptococcus pneumoniae R6	53.191	100	0.534
comEA/celA/cilE	Streptococcus pneumoniae Rx1	53.191	100	0.534
comEA/celA/cilE	Streptococcus mitis NCTC 12261	52.34	100	0.526
comEA/celA/cilE	Streptococcus mitis SK321	51.931	99.573	0.517
comEA	Lactococcus lactis subsp. cremoris KW2	41.631	99.573	0.415
comEA	Streptococcus thermophilus LMD-9	57.333	64.103	0.368