Detailed information NTG0537234

Bioinformatically predicted

Overview

• Name: comEC/celB
• Type: Machinery gene
• Locus tag: I6K87_RS03120
• Genome accession: NZ_CP069892
• Coordinates: 632130..634358 (-)
• Length: 742 a.a.
• NCBI ID: WP_204982753.1
• Uniprot ID: -
• Organism: Streptococcus anginosus strain FDAARGOS_1357
• Function: ssDNA transport into the cell (predicted from homology) DNA binding and uptake

Genomic Context

Location: 627130..639358

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
I6K87_RS03090 (I6K87_03090)	-	627347..628624 (-)	1278	WP_070497022.1	dihydroorotase	-
I6K87_RS03095 (I6K87_03095)	-	628637..629107 (-)	471	WP_204982751.1	NUDIX hydrolase	-
I6K87_RS03100 (I6K87_03100)	-	629144..629797 (-)	654	WP_049517463.1	uracil-DNA glycosylase	-
I6K87_RS03105 (I6K87_03105)	-	629821..630807 (-)	987	WP_204982752.1	Gfo/Idh/MocA family protein	-
I6K87_RS03110 (I6K87_03110)	-	631050..631208 (+)	159	WP_003042740.1	hypothetical protein	-
I6K87_RS03115 (I6K87_03115)	-	631351..632049 (-)	699	WP_003029857.1	DUF805 domain-containing protein	-
I6K87_RS03120 (I6K87_03120)	comEC/celB	632130..634358 (-)	2229	WP_204982753.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
I6K87_RS03125 (I6K87_03125)	comEA/celA/cilE	634342..635046 (-)	705	WP_204982754.1	helix-hairpin-helix domain-containing protein	Machinery gene
I6K87_RS03130 (I6K87_03130)	smpB	635228..635695 (-)	468	WP_022526922.1	SsrA-binding protein SmpB	-
I6K87_RS03135 (I6K87_03135)	rnr	635658..637991 (-)	2334	WP_204982755.1	ribonuclease R	-
I6K87_RS03140 (I6K87_03140)	secG	638083..638316 (-)	234	WP_003024744.1	preprotein translocase subunit SecG	-
I6K87_RS03145 (I6K87_03145)	rpmG	638356..638505 (-)	150	WP_003024746.1	50S ribosomal protein L33	-

Sequence

Protein

• Length: 742 a.a.
• Molecular weight: 85037.92 Da
• Isoelectric Point: 10.0271

>NTDB_id=537234 I6K87_RS03120 WP_204982753.1 632130..634358(-) (comEC/celB) [Streptococcus anginosus strain FDAARGOS_1357]
MSQWIKRFPIKPIYIAFLLVWLYFAIYQSSWLGWLGFIFLVICLFRFYSPKECFMTFMILICFAGFFFIRREIAEQKTKV
EPSPIRQVAVLPDTIKVNGDSLSFRGKANGQTYQVYYKLKSKEEQLAFQNLSSLVTLTVEGEFEIPEKKRNFAGFDYQSY
LKTQGIYRILKVDTILSSQDRISLHPFEWLSSWRRKALVFIKNHFPNPMSNYMTGLLFGALDTSFDEMSNLYSSLGIIHL
FALSGMQVGFFMEGFRKLLLRLGLTQEMVHKCQYPFSFFYAGMTGFSVSVVRSLVQKLLSQHGITKLDNFALTMMILSLI
MPSFLLTAGGVLSCAYAFVISVIDFESLTSWRNIVVESSVISLGVLPILIFYFGEFQPWSILLTFVFSLIFDAMMLPGLT
LIFLFSPLIKLTQVNFLFEGLENSIRWIASVFGRPIVFGQPSPLLLIVMLLVLAILYDIRKNKKWVIFLSLLLSLLFFIN
KFPLQNEITMVDVGQGDSIFLRDWKGRNVLIDVGGREEIRTKEAWQKRATGSNAEKTLIPYLKSRGVDTIDTLVLTNPNP
DYAGDVLEVAKKFAIKKIYIARSSLSNADFLEKLRKINTFIHVVKQGDKLPIFDHHLKVLSSASKNDHSIVLYGRFFRTR
FLFASDLKEEGEAKLMQHYPKLKTDVLKVGQHGAKNSSHSKFLQQIEPAVALISVGKNNQSKQPSQDTIERFAQLPAKVY
RTDEQGAVKFSGWTNWRLEMVK

Nucleotide

• Length: 2229 bp

>NTDB_id=537234 I6K87_RS03120 WP_204982753.1 632130..634358(-) (comEC/celB) [Streptococcus anginosus strain FDAARGOS_1357]
ATGTCACAGTGGATTAAAAGATTTCCGATTAAGCCGATTTACATTGCTTTTTTGCTCGTCTGGTTGTATTTTGCAATCTA
TCAAAGTAGCTGGTTAGGCTGGTTGGGTTTTATCTTTCTGGTGATTTGTCTTTTTCGCTTTTATTCACCGAAAGAATGTT
TCATGACCTTCATGATTCTAATTTGTTTTGCTGGTTTTTTCTTTATTCGTAGGGAAATAGCAGAGCAGAAGACGAAAGTA
GAACCTTCTCCCATAAGACAAGTGGCAGTTCTACCTGACACGATTAAGGTAAATGGTGATTCGCTTTCTTTTCGTGGTAA
AGCTAATGGGCAGACTTATCAAGTTTACTACAAATTGAAATCAAAGGAAGAACAGTTGGCTTTTCAAAATCTCTCTAGTC
TGGTTACATTGACTGTTGAAGGGGAATTTGAAATCCCTGAGAAGAAGCGTAATTTTGCTGGTTTTGATTACCAATCCTAT
TTAAAAACGCAAGGGATTTATCGAATTTTAAAAGTGGATACCATTTTATCGAGCCAAGATAGAATCAGCTTGCACCCTTT
TGAGTGGCTTTCTAGCTGGCGAAGAAAAGCACTGGTATTTATCAAGAACCATTTTCCAAATCCGATGAGTAATTACATGA
CAGGACTCTTATTTGGTGCCTTGGATACATCCTTTGACGAAATGAGCAATCTTTACTCTAGCTTGGGGATTATTCATTTA
TTTGCGCTGTCTGGCATGCAAGTTGGCTTTTTTATGGAGGGTTTTCGTAAGTTGCTGTTAAGGCTGGGTCTTACACAGGA
AATGGTTCATAAATGCCAATATCCATTTTCTTTCTTCTATGCGGGAATGACTGGATTTTCAGTATCCGTTGTACGGAGCT
TAGTTCAGAAATTATTGTCGCAACATGGTATCACTAAGTTAGATAATTTTGCTTTAACGATGATGATATTGTCCTTGATT
ATGCCTTCCTTTCTTTTAACGGCGGGAGGAGTTCTCTCTTGCGCCTATGCTTTTGTTATTAGTGTGATAGATTTTGAAAG
TCTGACTTCTTGGCGAAACATTGTTGTAGAGAGCAGTGTCATTTCGCTTGGTGTTTTACCGATTCTAATCTTTTATTTTG
GTGAATTTCAACCTTGGTCTATTTTGTTGACATTTGTTTTTTCACTGATTTTCGATGCAATGATGTTGCCAGGATTGACG
TTGATTTTTCTTTTTTCGCCTTTGATAAAGCTAACTCAGGTCAATTTTCTATTTGAAGGGTTAGAAAATAGCATTCGTTG
GATAGCAAGTGTCTTTGGCAGACCAATCGTTTTTGGGCAACCCAGTCCGCTTTTGCTGATTGTTATGCTACTTGTACTGG
CTATTTTGTATGATATTAGAAAAAATAAAAAATGGGTAATATTTCTTAGTCTGCTTCTTTCATTACTCTTTTTCATAAAT
AAATTTCCCTTGCAAAATGAGATCACAATGGTTGATGTTGGGCAGGGAGATAGTATTTTTCTGAGAGACTGGAAAGGACG
AAATGTATTGATTGATGTTGGTGGACGTGAGGAAATTAGAACAAAAGAAGCTTGGCAGAAACGAGCAACTGGCTCAAATG
CAGAGAAAACTTTGATTCCTTACTTAAAAAGTCGTGGTGTAGATACGATTGATACTTTAGTCTTAACAAATCCTAATCCA
GATTATGCAGGAGATGTATTAGAAGTTGCTAAAAAATTTGCAATAAAGAAAATTTATATTGCCAGAAGTAGTCTAAGCAA
TGCAGATTTTCTAGAGAAATTAAGGAAAATAAACACATTCATTCATGTTGTAAAACAAGGCGACAAACTTCCTATTTTTG
ATCATCATTTGAAAGTTCTTTCGAGTGCTAGCAAGAACGACCATTCGATTGTTTTATATGGTCGGTTTTTCCGTACAAGA
TTTTTATTTGCGAGCGACTTGAAAGAAGAGGGCGAAGCAAAGTTAATGCAGCATTATCCAAAGTTGAAAACAGATGTTTT
GAAAGTCGGACAGCATGGAGCCAAAAATTCATCACATTCAAAGTTTTTACAGCAAATAGAGCCCGCAGTTGCGCTCATTT
CTGTTGGGAAAAATAATCAATCTAAGCAACCAAGTCAAGATACAATAGAGCGATTTGCACAATTGCCTGCTAAAGTCTAT
CGGACAGATGAACAAGGGGCAGTTAAATTTTCAGGGTGGACAAACTGGCGATTAGAGATGGTCAAGTAA

Domains

Predicted by InterproScan.

• Competence protein (Competence) (216-460)

• Metallo-beta-lactamase superfamily (Lactamase_B) (492-594)

• Domain of unknown function (DUF4131) (DUF4131) (29-175)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comEC/celB	Streptococcus mitis SK321	55.154	100	0.555
comEC/celB	Streptococcus mitis NCTC 12261	54.558	100	0.549
comEC/celB	Streptococcus pneumoniae TIGR4	54.083	100	0.544
comEC/celB	Streptococcus pneumoniae Rx1	53.28	100	0.536
comEC/celB	Streptococcus pneumoniae D39	53.28	100	0.536
comEC/celB	Streptococcus pneumoniae R6	53.28	100	0.536
comEC	Lactococcus lactis subsp. cremoris KW2	47.043	100	0.472