Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilC   Type   Machinery gene
Locus tag   JOS67_RS03480 Genome accession   NZ_CP069195
Coordinates   610755..611978 (-) Length   407 a.a.
NCBI ID   WP_074191781.1    Uniprot ID   A0AA92R805
Organism   Vibrio diabolicus strain SLV18     
Function   type IV pilus biogenesis and function (predicted from homology)   
DNA binding and uptake

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Genomic island 605426..623422 610755..611978 within 0


Gene organization within MGE regions


Location: 605426..623422
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  JOS67_RS03440 (JOS67_03435) rpsP 605426..605674 (+) 249 WP_005379962.1 30S ribosomal protein S16 -
  JOS67_RS03445 (JOS67_03440) rimM 605704..606252 (+) 549 WP_005379964.1 ribosome maturation factor RimM -
  JOS67_RS03450 (JOS67_03445) trmD 606280..607023 (+) 744 WP_203346927.1 tRNA (guanosine(37)-N1)-methyltransferase TrmD -
  JOS67_RS03455 (JOS67_03450) rplS 607065..607418 (+) 354 WP_005379971.1 50S ribosomal protein L19 -
  JOS67_RS03460 (JOS67_03455) yacG 608084..608278 (-) 195 WP_005396692.1 DNA gyrase inhibitor YacG -
  JOS67_RS03465 (JOS67_03460) zapD 608438..609178 (-) 741 WP_005396691.1 cell division protein ZapD -
  JOS67_RS03470 (JOS67_03465) coaE 609206..609820 (-) 615 WP_047008979.1 dephospho-CoA kinase -
  JOS67_RS03475 (JOS67_03470) pilD 609821..610690 (-) 870 WP_012841418.1 prepilin peptidase Machinery gene
  JOS67_RS03480 (JOS67_03475) pilC 610755..611978 (-) 1224 WP_074191781.1 type II secretion system F family protein Machinery gene
  JOS67_RS03485 (JOS67_03480) pilB 612002..613687 (-) 1686 WP_203346928.1 type IV-A pilus assembly ATPase PilB Machinery gene
  JOS67_RS03490 (JOS67_03485) pilA 613699..614136 (-) 438 WP_203346929.1 pilin Machinery gene
  JOS67_RS03495 (JOS67_03490) nadC 614399..615286 (-) 888 WP_047102656.1 carboxylating nicotinate-nucleotide diphosphorylase -
  JOS67_RS03500 (JOS67_03495) ampD 615379..615930 (+) 552 WP_012841421.1 1,6-anhydro-N-acetylmuramyl-L-alanine amidase AmpD -
  JOS67_RS03505 (JOS67_03500) pdhR 616336..617103 (+) 768 WP_005396680.1 pyruvate dehydrogenase complex transcriptional repressor PdhR -
  JOS67_RS03510 (JOS67_03505) aceE 617152..619815 (+) 2664 WP_005396679.1 pyruvate dehydrogenase (acetyl-transferring), homodimeric type -
  JOS67_RS03515 (JOS67_03510) aceF 619835..621727 (+) 1893 WP_203346930.1 pyruvate dehydrogenase complex dihydrolipoyllysine-residue acetyltransferase -
  JOS67_RS03520 (JOS67_03515) lpdA 621995..623422 (+) 1428 WP_005379993.1 dihydrolipoyl dehydrogenase -

Sequence

Protein


Download         Length: 407 a.a.        Molecular weight: 45327.52 Da        Isoelectric Point: 10.3992

>NTDB_id=532822 JOS67_RS03480 WP_074191781.1 610755..611978(-) (pilC) [Vibrio diabolicus strain SLV18]
MKTTTPQLKNFRWKGINSSGKKTSGQTLAMTEIEVRERLDAQHIKIKKLKKSSISFLTKLSHRVKGRDITVFTRQISTML
ITGVPLVQALKLVSENHKKAEMKSILMSVTRAVEAGTPMSKAMRTASEHFDPLYTDLIATGEQSGNLAEVFERLATYREK
NEQLRAKVIKALIYPAMVVLVALGVSFIMLTKVIPEFEKMFVGFGADLPWFTRQVLDLSAWTQNWSPFIALGSISLFISA
RILSKRSDSFRLMLNRSVLKFPVLGPVLSKAAIAKFSRTLATSFTAGIPILTSLKTTSKTSGNLHYQLAIEEVYRDTAAG
MPMYVAMRNCNVFPELVLQMVMIGEESGRLDDMLNKVATIYEFEVDNTVDNLSKILEPLIIVFLGIVVGGLVTAMYLPIF
NLMSVLG

Nucleotide


Download         Length: 1224 bp        

>NTDB_id=532822 JOS67_RS03480 WP_074191781.1 610755..611978(-) (pilC) [Vibrio diabolicus strain SLV18]
ATGAAAACCACTACACCACAACTTAAAAACTTCCGCTGGAAAGGCATCAACAGTTCAGGCAAAAAGACGTCTGGACAAAC
CCTCGCGATGACAGAAATTGAAGTACGCGAGCGTCTAGACGCACAACACATCAAGATCAAGAAGTTAAAGAAAAGCAGTA
TCTCGTTTCTCACTAAACTCAGCCATCGCGTGAAAGGCAGAGACATCACGGTGTTTACCCGGCAAATTTCGACGATGTTG
ATAACCGGTGTCCCCTTAGTTCAGGCTTTAAAATTGGTATCAGAAAACCACAAAAAAGCAGAGATGAAATCCATTTTGAT
GAGCGTGACACGCGCCGTTGAAGCGGGTACGCCCATGTCAAAAGCCATGCGCACTGCAAGTGAACACTTTGACCCACTCT
ATACCGACCTTATCGCCACAGGTGAGCAATCCGGTAACTTAGCAGAAGTATTCGAGCGCTTAGCCACCTACCGAGAAAAA
AATGAACAACTCCGTGCGAAAGTGATCAAAGCTTTGATTTACCCAGCCATGGTAGTGCTAGTAGCGTTAGGCGTCTCGTT
TATCATGCTCACCAAAGTCATTCCCGAGTTTGAAAAAATGTTTGTTGGTTTTGGTGCTGACTTACCTTGGTTTACCAGGC
AAGTATTAGATCTTTCCGCCTGGACACAAAACTGGAGCCCATTTATAGCACTAGGCTCTATCAGTCTATTCATCTCGGCG
AGAATCCTCTCTAAGCGTTCAGATTCTTTTCGCTTAATGCTCAATCGCTCTGTGCTTAAATTTCCTGTTCTTGGCCCTGT
ATTATCAAAAGCCGCTATCGCCAAATTTAGTCGAACACTCGCCACAAGCTTTACAGCGGGTATTCCAATTCTAACCAGTT
TAAAAACCACATCAAAAACCTCAGGAAACTTACACTATCAACTCGCCATAGAAGAAGTTTACCGTGATACCGCCGCAGGT
ATGCCAATGTATGTTGCCATGCGTAACTGTAATGTGTTCCCTGAATTAGTGTTACAAATGGTCATGATCGGTGAAGAGTC
TGGTCGACTTGACGATATGCTCAATAAAGTTGCAACGATCTACGAGTTTGAAGTCGATAACACCGTCGACAACCTTAGTA
AAATTCTAGAGCCGCTAATTATCGTTTTTTTAGGCATCGTTGTTGGCGGATTAGTGACAGCAATGTACTTGCCAATCTTT
AACTTAATGAGTGTATTGGGCTAG

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(72-195)

Type II secretion system (T2SS), protein F (T2SSF)

(276-398)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilC Vibrio campbellii strain DS40M4

87.469

100

0.875
  pilC Vibrio cholerae strain A1552

73.827

99.509

0.735
  pilC Acinetobacter baylyi ADP1

43

98.28

0.423
  pilC Acinetobacter baumannii D1279779

41.439

99.017

0.41
  pilG Neisseria gonorrhoeae MS11

40.494

99.509

0.403
  pilC Legionella pneumophila strain ERS1305867

40.295

100

0.403
  pilG Neisseria meningitidis 44/76-A

40.247

99.509

0.4
  pilC Pseudomonas stutzeri DSM 10701

40.909

97.297

0.398