NTDB

Overview

Name	comEA/celA/cilE	Type	Machinery gene
Locus tag	I6J13_RS01680	Genome accession	NZ_CP068213
Coordinates	345675..346379 (+)	Length	234 a.a.
NCBI ID	WP_006269533.1	Uniprot ID	A0AAD2Y554
Organism	Streptococcus constellatus strain FDAARGOS_1156
Function	dsDNA binding to the cell surface (predicted from homology) DNA binding and uptake

Genomic Context

Location: 340675..351379

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
I6J13_RS01655 (I6J13_01655)	-	341034..342239 (+)	1206	WP_171004446.1	multidrug efflux MFS transporter	-
I6J13_RS01660 (I6J13_01660)	rpmG	342223..342372 (+)	150	WP_003024746.1	50S ribosomal protein L33	-
I6J13_RS01665 (I6J13_01665)	secG	342412..342645 (+)	234	WP_003024744.1	preprotein translocase subunit SecG	-
I6J13_RS01670 (I6J13_01670)	rnr	342738..344874 (+)	2137	Protein_334	ribonuclease R	-
I6J13_RS01675 (I6J13_01675)	smpB	345040..345507 (+)	468	WP_003034458.1	SsrA-binding protein SmpB	-
I6J13_RS01680 (I6J13_01680)	comEA/celA/cilE	345675..346379 (+)	705	WP_006269533.1	helix-hairpin-helix domain-containing protein	Machinery gene
I6J13_RS01685 (I6J13_01685)	comEC/celB	346363..348591 (+)	2229	WP_037565577.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
I6J13_RS01690 (I6J13_01690)	-	348671..349159 (+)	489	WP_006269494.1	DUF805 domain-containing protein	-
I6J13_RS09380	-	349181..349390 (+)	210	WP_022524619.1	hypothetical protein	-
I6J13_RS01695 (I6J13_01695)	-	349835..350821 (+)	987	WP_006269544.1	Gfo/Idh/MocA family protein	-

Sequence

Protein

Download Length: 234 a.a. Molecular weight: 25346.67 Da Isoelectric Point: 8.2610

                                >NTDB_id=528022 I6J13_RS01680 WP_006269533.1 345675..346379(+) (comEA/celA/cilE) [Streptococcus constellatus strain FDAARGOS_1156]

MLEVIITKIKEYKILVGLSLIGLIIAGFFLMTSKSARQSNVGDIAQEATNAKLERKETSTETKKKQQKEETESQKNLASE

ELEFLTVDVKGAVKNPGIYQLKKTSRINDAIQKAGGLTTDADSKSINLAQKLTDEAVIYVATMGENVTNAASNNGQTLTT

DTDGTAAQKGNKVNLNKANLSDLQSISGIGQKRAQDILDYREANGKFNSVDDLKNISGVGAKTLEKLKEYVTVD

Nucleotide

Download Length: 705 bp

                                >NTDB_id=528022 I6J13_RS01680 WP_006269533.1 345675..346379(+) (comEA/celA/cilE) [Streptococcus constellatus strain FDAARGOS_1156]

ATGTTAGAGGTAATCATCACAAAAATAAAAGAGTATAAAATTTTAGTTGGTTTAAGCCTGATTGGTTTGATCATAGCAGG

ATTTTTTCTGATGACTAGTAAATCTGCTAGACAATCTAATGTGGGAGATATTGCACAAGAGGCCACAAATGCAAAACTAG

AACGGAAAGAAACTTCAACTGAAACGAAGAAAAAACAACAGAAAGAAGAAACAGAATCTCAAAAGAATTTAGCGAGTGAA

GAATTGGAATTTTTAACTGTAGATGTTAAAGGTGCTGTTAAAAATCCAGGTATTTATCAATTAAAAAAAACAAGCCGAAT

AAATGATGCTATCCAAAAAGCGGGTGGACTAACGACAGACGCTGACAGCAAATCTATCAATTTGGCTCAAAAACTAACAG

ATGAGGCTGTGATTTATGTGGCAACTATGGGTGAAAATGTAACAAATGCTGCAAGTAATAATGGACAAACTTTAACGACA

GATACCGATGGAACTGCGGCACAAAAAGGGAATAAGGTCAATCTAAATAAGGCTAATTTGTCTGATTTACAGTCTATTTC

TGGTATTGGACAAAAGCGCGCCCAAGATATTTTAGATTATCGTGAGGCAAATGGAAAATTTAATTCTGTTGATGATCTTA

AAAATATATCAGGAGTTGGTGCTAAAACATTAGAGAAATTGAAAGAATATGTCACAGTGGATTAA

Domains

Predicted by InterproScan.

SLBB domain (SLBB)

(87-140)

Helix-hairpin-helix motif (HHH_3)

(169-232)

Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.

3D structure

Source	ID	Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.

Visualization of predicted probability:

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	H_a-value
comEA/celA/cilE	Streptococcus mitis NCTC 12261	51.502	99.573	0.513
comEA/celA/cilE	Streptococcus pneumoniae TIGR4	51.073	99.573	0.509
comEA/celA/cilE	Streptococcus mitis SK321	51.073	99.573	0.509
comEA/celA/cilE	Streptococcus pneumoniae Rx1	50.644	99.573	0.504
comEA/celA/cilE	Streptococcus pneumoniae D39	50.644	99.573	0.504
comEA/celA/cilE	Streptococcus pneumoniae R6	50.644	99.573	0.504
comEA	Streptococcus thermophilus LMD-9	41.702	100	0.419
comEA	Lactococcus lactis subsp. cremoris KW2	36.91	99.573	0.368

Detailed information NTG0528022