Detailed information NTG0528023

Bioinformatically predicted

Overview

• Name: comEC/celB
• Type: Machinery gene
• Locus tag: I6J13_RS01685
• Genome accession: NZ_CP068213
• Coordinates: 346363..348591 (+)
• Length: 742 a.a.
• NCBI ID: WP_037565577.1
• Uniprot ID: -
• Organism: Streptococcus constellatus strain FDAARGOS_1156
• Function: ssDNA transport into the cell (predicted from homology) DNA binding and uptake

Genomic Context

Location: 341363..353591

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
I6J13_RS01660 (I6J13_01660)	rpmG	342223..342372 (+)	150	WP_003024746.1	50S ribosomal protein L33	-
I6J13_RS01665 (I6J13_01665)	secG	342412..342645 (+)	234	WP_003024744.1	preprotein translocase subunit SecG	-
I6J13_RS01670 (I6J13_01670)	rnr	342738..344874 (+)	2137	Protein_334	ribonuclease R	-
I6J13_RS01675 (I6J13_01675)	smpB	345040..345507 (+)	468	WP_003034458.1	SsrA-binding protein SmpB	-
I6J13_RS01680 (I6J13_01680)	comEA/celA/cilE	345675..346379 (+)	705	WP_006269533.1	helix-hairpin-helix domain-containing protein	Machinery gene
I6J13_RS01685 (I6J13_01685)	comEC/celB	346363..348591 (+)	2229	WP_037565577.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
I6J13_RS01690 (I6J13_01690)	-	348671..349159 (+)	489	WP_006269494.1	DUF805 domain-containing protein	-
I6J13_RS09380	-	349181..349390 (+)	210	WP_022524619.1	hypothetical protein	-
I6J13_RS01695 (I6J13_01695)	-	349835..350821 (+)	987	WP_006269544.1	Gfo/Idh/MocA family protein	-
I6J13_RS01700 (I6J13_01700)	-	350846..351499 (+)	654	WP_006269516.1	uracil-DNA glycosylase	-
I6J13_RS01705 (I6J13_01705)	-	351508..351978 (+)	471	WP_006269550.1	8-oxo-dGTP diphosphatase	-
I6J13_RS01710 (I6J13_01710)	-	351990..353264 (+)	1275	WP_006269592.1	dihydroorotase	-

Sequence

Protein

• Length: 742 a.a.
• Molecular weight: 85433.42 Da
• Isoelectric Point: 10.0339

>NTDB_id=528023 I6J13_RS01685 WP_037565577.1 346363..348591(+) (comEC/celB) [Streptococcus constellatus strain FDAARGOS_1156]
MSQWIKIFPIKPIYIAFLLVWLYFAIYQSSWLAWFCFIFLIIRLFVLYSPKKCFTTLMFLACFAAFFFVRREMAEWQTKA
EPSSVRQVAVLPDTIKVNGDSLSFRGKANGQTYQIYYKLKSKEEQLAFQNLSSLVTLTVEGEFESPEKQRNFSGFDYQAY
LKTQGIYRILKVDQILSSQDRVSFQPFEWLSNWRRKALVFIKRNFPNPMNHYMTGLLFGALETDFDEMSDLYSSLGIIHL
FALSGMQVGFFMEGFRKLLLKLGLTKEMVHKCQYPFSFFYAGMTGFSVSVVRSLIQKLLSQHGITKLDNFALTIMVLSLL
MPSFLLTAGGVLSCAYAFVISVIDFESLTSWRKVVVESSIISLGVLPILIFYFGEFQPWSILLTFVFSLIFDIVMLPGLT
LIFLISPFIKLIQVNFLFEGLENSIRWIANVFGRPIVFGQPSSLLLVVMLLVLAILYDVRKNKKWVILLSLCLAILFFIT
KFPFQNEITMVDVGRGDSLFLRDWKGRNVLIDVGGREEIRTKESWQKRTTKSNAEKTLIPYLKSRGIDTIDTLILTNPNA
DYAGDVIKVVKKFAVKKIFISRSSLNDADFLNKLKETRAFVHVVKQGDKLPIFDHHLQVLSGTNKNDQSLVLYGQFFRTR
FLFMSNLTEEDEVKLMQLYPKLKTDVLKVGQHGAKNSSHSKFLQQIEPAVALISVGKNNQSKSPNQEMIERLNRLNAKIY
RTDERGAIKFSGWTKWQLETVQ

Nucleotide

• Length: 2229 bp

>NTDB_id=528023 I6J13_RS01685 WP_037565577.1 346363..348591(+) (comEC/celB) [Streptococcus constellatus strain FDAARGOS_1156]
ATGTCACAGTGGATTAAGATATTTCCGATTAAACCAATTTACATTGCTTTCTTACTTGTCTGGCTATATTTTGCAATCTA
TCAAAGTAGCTGGTTGGCTTGGTTTTGTTTTATTTTTCTAATAATCCGTCTTTTTGTCCTTTATTCACCGAAAAAATGTT
TCACAACTTTAATGTTTCTCGCTTGTTTTGCTGCTTTTTTCTTTGTTCGTAGAGAAATGGCAGAGTGGCAAACAAAAGCA
GAACCTTCTTCTGTAAGACAAGTAGCAGTTCTACCTGACACGATTAAGGTAAATGGAGATTCGCTTTCTTTTCGCGGCAA
AGCAAATGGGCAGACTTATCAAATTTACTACAAATTGAAATCAAAAGAAGAACAGTTGGCTTTTCAAAATCTATCCAGTC
TTGTCACATTAACTGTTGAGGGGGAATTTGAATCTCCTGAAAAGCAACGCAATTTTTCTGGTTTTGATTATCAAGCCTAT
CTAAAAACGCAAGGGATTTATCGGATTTTAAAGGTGGATCAAATTTTGTCTAGTCAAGATAGGGTTAGCTTCCAACCGTT
TGAGTGGTTGTCTAACTGGCGAAGAAAGGCATTGGTTTTCATTAAGAGAAATTTTCCAAATCCGATGAATCATTACATGA
CAGGGCTCTTATTTGGCGCATTAGAGACAGATTTTGATGAAATGAGTGATCTTTATTCTAGCTTGGGAATTATTCATTTA
TTTGCGTTATCTGGCATGCAAGTTGGCTTTTTTATGGAAGGATTTCGTAAGTTGCTTTTGAAGCTGGGACTTACGAAGGA
AATGGTTCATAAATGCCAATATCCGTTTTCTTTCTTTTATGCAGGAATGACTGGATTTTCAGTATCCGTTGTACGGAGTT
TAATTCAGAAATTATTGTCGCAACATGGTATCACTAAATTAGATAATTTTGCTTTAACAATAATGGTGTTGTCCTTGCTT
ATGCCATCTTTTCTTTTAACGGCAGGAGGAGTTCTCTCCTGTGCCTATGCTTTTGTTATTAGTGTTATAGATTTTGAAAG
TCTGACTTCTTGGAGAAAAGTTGTGGTAGAGAGTAGTATCATTTCACTTGGTGTTTTACCGATTCTAATCTTTTATTTTG
GAGAATTTCAACCTTGGTCTATTTTATTGACATTTGTTTTTTCACTAATTTTTGATATAGTGATGCTACCGGGTTTAACA
CTGATTTTTCTCATTTCACCTTTCATAAAGCTCATTCAAGTAAATTTTCTTTTTGAAGGCTTAGAAAATAGTATTCGTTG
GATAGCAAATGTCTTTGGCAGACCAATCGTTTTTGGGCAACCTAGCTCGCTTTTATTAGTTGTTATGCTGCTTGTACTGG
CTATTTTGTATGATGTTAGAAAAAATAAAAAATGGGTGATATTGCTCAGCTTGTGTCTTGCTATACTATTTTTTATAACT
AAATTTCCTTTTCAAAATGAGATCACAATGGTTGATGTTGGACGGGGAGATAGTCTTTTTTTGAGAGACTGGAAAGGTAG
AAATGTATTGATTGACGTTGGAGGACGTGAAGAAATTAGAACAAAAGAATCTTGGCAAAAACGAACAACTAAATCAAATG
CGGAGAAAACTTTGATTCCTTACCTAAAAAGTCGTGGTATAGATACGATTGATACTCTAATCTTAACAAATCCTAATGCA
GATTATGCGGGAGATGTAATAAAAGTGGTTAAAAAGTTTGCGGTAAAGAAAATTTTTATTTCCAGAAGTAGTTTGAATGA
TGCAGACTTTTTAAATAAATTAAAGGAGACAAGAGCATTTGTTCATGTCGTAAAACAAGGAGACAAACTTCCTATTTTTG
ATCATCATTTGCAAGTTCTTTCTGGTACGAATAAGAATGATCAATCGCTAGTTTTATATGGTCAATTTTTTCGTACAAGG
TTTTTATTTATGAGCAATTTAACAGAAGAGGATGAAGTAAAGCTAATGCAACTTTATCCAAAGCTAAAAACAGATGTCTT
GAAGGTTGGGCAACATGGAGCTAAAAATTCATCACATTCAAAATTTTTACAGCAAATAGAACCGGCAGTTGCACTCATTT
CTGTTGGGAAAAATAACCAATCCAAATCTCCGAATCAAGAAATGATAGAGCGATTGAATCGCTTAAATGCGAAGATTTAT
CGAACAGATGAACGAGGGGCGATCAAGTTTTCAGGATGGACAAAATGGCAATTAGAAACTGTTCAATAG

Domains

Predicted by InterproScan.

• Competence protein (Competence) (216-460)

• Metallo-beta-lactamase superfamily (Lactamase_B) (496-578)

• Domain of unknown function (DUF4131) (DUF4131) (30-175)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comEC/celB	Streptococcus mitis SK321	54.351	100	0.547
comEC/celB	Streptococcus mitis NCTC 12261	54.29	100	0.546
comEC/celB	Streptococcus pneumoniae TIGR4	53.548	100	0.539
comEC/celB	Streptococcus pneumoniae Rx1	52.744	100	0.531
comEC/celB	Streptococcus pneumoniae D39	52.744	100	0.531
comEC/celB	Streptococcus pneumoniae R6	52.744	100	0.531
comEC	Lactococcus lactis subsp. cremoris KW2	46.299	100	0.464