Detailed information    

insolico Bioinformatically predicted

Overview

Name   dprA/cilB/dalA   Type   Machinery gene
Locus tag   I6J12_RS04395 Genome accession   NZ_CP068060
Coordinates   922324..923166 (-) Length   280 a.a.
NCBI ID   WP_003034514.1    Uniprot ID   I0SJ02
Organism   Streptococcus anginosus strain FDAARGOS_1155     
Function   ssDNA binding; loading RecA onto ssDNA (predicted from homology)   
DNA processing

Genomic Context

Location: 917324..928166
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  I6J12_RS04375 (I6J12_04375) - 917528..918352 (-) 825 WP_003034490.1 alpha/beta hydrolase -
  I6J12_RS04380 (I6J12_04380) trmFO 918484..919818 (-) 1335 WP_003034472.1 methylenetetrahydrofolate--tRNA-(uracil(54)- C(5))-methyltransferase (FADH(2)-oxidizing) TrmFO -
  I6J12_RS04385 (I6J12_04385) - 919992..920129 (-) 138 Protein_878 phosphoribosylanthranilate isomerase -
  I6J12_RS04390 (I6J12_04390) topA 920145..922238 (-) 2094 WP_100207875.1 type I DNA topoisomerase -
  I6J12_RS04395 (I6J12_04395) dprA/cilB/dalA 922324..923166 (-) 843 WP_003034514.1 DNA-processing protein DprA Machinery gene
  I6J12_RS04400 (I6J12_04400) - 923249..923805 (-) 557 Protein_881 sugar O-acetyltransferase -
  I6J12_RS04405 (I6J12_04405) - 923795..924623 (-) 829 Protein_882 PRD domain-containing protein -
  I6J12_RS04410 (I6J12_04410) - 924620..925402 (-) 783 WP_003034469.1 ribonuclease HII -
  I6J12_RS04415 (I6J12_04415) ylqF 925389..926240 (-) 852 WP_003034464.1 ribosome biogenesis GTPase YlqF -
  I6J12_RS04420 (I6J12_04420) - 926358..927275 (-) 918 WP_003034427.1 MBL fold metallo-hydrolase -

Sequence

Protein


Download         Length: 280 a.a.        Molecular weight: 31111.61 Da        Isoelectric Point: 5.2196

>NTDB_id=526798 I6J12_RS04395 WP_003034514.1 922324..923166(-) (dprA/cilB/dalA) [Streptococcus anginosus strain FDAARGOS_1155]
MDNFDIYKLKEAGLTNQQVINVLSYAEIQEKELSVKDMAVVSECRNPALFIEKYLQLDDDLLRQEFEKFPSFSILDDVYP
WDLSEIYNPPVLLFYKGNLDLLKLPKVAVVGSRNSSRVGSQSVQKIVKELNNELVIVSGLARGIDTSAHMAALQNGGRTI
AVIGTGLDVFYPRANKKLQSYLGEHHLVLSEYGSEAEPLKFHFPERNRIIAGLCRGVIVAEAKMRSGSLITCERAMEEGR
DVFAIPGSILDGRSDGCHHLIQEGAKCVTSGADVLSEFQF

Nucleotide


Download         Length: 843 bp        

>NTDB_id=526798 I6J12_RS04395 WP_003034514.1 922324..923166(-) (dprA/cilB/dalA) [Streptococcus anginosus strain FDAARGOS_1155]
ATGGATAATTTTGATATTTATAAATTAAAAGAAGCTGGCTTGACCAATCAGCAGGTCATCAATGTTCTCTCGTATGCTGA
GATACAAGAAAAAGAATTATCGGTAAAAGATATGGCAGTTGTTTCAGAATGCCGCAATCCTGCTCTTTTCATTGAAAAAT
ATCTGCAGCTAGATGATGATTTATTACGTCAAGAATTTGAAAAATTTCCGTCTTTTTCTATCTTGGATGATGTGTATCCT
TGGGATTTGAGCGAAATTTACAATCCACCCGTTCTTCTTTTCTACAAAGGAAACTTAGATTTATTGAAATTACCGAAAGT
AGCCGTTGTGGGAAGTCGGAATAGTAGCCGAGTAGGTAGTCAATCCGTTCAAAAGATTGTTAAAGAGCTAAACAATGAAT
TGGTTATCGTGAGTGGTTTAGCACGCGGAATTGATACCTCGGCTCACATGGCAGCATTGCAAAATGGTGGTCGAACAATT
GCAGTTATCGGAACGGGTCTAGACGTTTTTTATCCAAGAGCGAATAAAAAACTCCAATCGTATTTGGGAGAACATCATCT
AGTACTTAGTGAATATGGTTCTGAAGCAGAGCCATTAAAATTTCATTTTCCAGAGCGTAATCGGATTATAGCAGGATTGT
GCAGAGGGGTTATTGTTGCTGAAGCCAAAATGCGCTCAGGAAGTTTAATTACTTGTGAGCGCGCAATGGAAGAAGGACGA
GATGTGTTTGCTATTCCAGGGTCAATTTTAGACGGCAGAAGTGATGGCTGTCATCATTTGATTCAAGAGGGTGCAAAGTG
TGTCACATCAGGCGCTGACGTACTTTCTGAATTCCAATTTTAA

Domains

Predicted by InterproScan.

DNA processing protein A sterile alpha motif domain (SAM_DprA)

(1-60)

DNA recombination-mediator protein A (DNA_processg_A)

(73-269)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB I0SJ02

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  dprA/cilB/dalA Streptococcus mitis NCTC 12261

76.429

100

0.764
  dprA/cilB/dalA Streptococcus pneumoniae Rx1

76.071

100

0.761
  dprA/cilB/dalA Streptococcus pneumoniae D39

76.071

100

0.761
  dprA/cilB/dalA Streptococcus pneumoniae R6

76.071

100

0.761
  dprA/cilB/dalA Streptococcus pneumoniae TIGR4

76.071

100

0.761
  dprA/cilB/dalA Streptococcus mitis SK321

75.714

100

0.757
  dprA Streptococcus mutans UA159

65

100

0.65
  dprA Lactococcus lactis subsp. cremoris KW2

57.857

100

0.579
  dprA Staphylococcus aureus N315

37.589

100

0.379
  dprA Legionella pneumophila strain ERS1305867

43.983

86.071

0.379
  dprA Staphylococcus aureus MW2

37.367

100

0.375