Detailed information    

insolico Bioinformatically predicted

Overview

Name   comEA/celA/cilE   Type   Machinery gene
Locus tag   I6J12_RS03910 Genome accession   NZ_CP068060
Coordinates   822711..823415 (+) Length   234 a.a.
NCBI ID   WP_003034448.1    Uniprot ID   I0SIU4
Organism   Streptococcus anginosus strain FDAARGOS_1155     
Function   dsDNA binding to the cell surface (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 817711..828415
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  I6J12_RS03885 (I6J12_03885) - 818072..819277 (+) 1206 WP_003034551.1 multidrug efflux MFS transporter -
  I6J12_RS03890 (I6J12_03890) rpmG 819261..819410 (+) 150 WP_003034401.1 50S ribosomal protein L33 -
  I6J12_RS03895 (I6J12_03895) secG 819450..819683 (+) 234 WP_003024744.1 preprotein translocase subunit SecG -
  I6J12_RS03900 (I6J12_03900) rnr 819774..822113 (+) 2340 WP_003034491.1 ribonuclease R -
  I6J12_RS03905 (I6J12_03905) smpB 822076..822543 (+) 468 WP_003034458.1 SsrA-binding protein SmpB -
  I6J12_RS03910 (I6J12_03910) comEA/celA/cilE 822711..823415 (+) 705 WP_003034448.1 helix-hairpin-helix domain-containing protein Machinery gene
  I6J12_RS03915 (I6J12_03915) comEC/celB 823399..825627 (+) 2229 WP_003034410.1 DNA internalization-related competence protein ComEC/Rec2 Machinery gene
  I6J12_RS03920 (I6J12_03920) - 825708..826400 (+) 693 WP_020999586.1 DUF805 domain-containing protein -
  I6J12_RS03925 (I6J12_03925) - 826905..827891 (+) 987 WP_003034384.1 Gfo/Idh/MocA family protein -

Sequence

Protein


Download         Length: 234 a.a.        Molecular weight: 25344.70 Da        Isoelectric Point: 9.4255

>NTDB_id=526796 I6J12_RS03910 WP_003034448.1 822711..823415(+) (comEA/celA/cilE) [Streptococcus anginosus strain FDAARGOS_1155]
MLEVIIKKIKEYKILVGLSLIGLIIAGFFLMTSKSARQSNVGDIAQEATNAKLERKETSTETKKKQQKEETESQKNLASE
ELEFLTVDVKGAVKNPGIYQLKKTSRINDAIQKAGGLTTDADSKSINLAQKLTDEAVIYVAAMGENVTNAASNNGQTLTT
DTNGTAAQKGNKVNLNKANLSDLQSISGIGQKRAQDILDYRESNGKFNSVDDLKNVSGVGAKTLEKLKEYVTVD

Nucleotide


Download         Length: 705 bp        

>NTDB_id=526796 I6J12_RS03910 WP_003034448.1 822711..823415(+) (comEA/celA/cilE) [Streptococcus anginosus strain FDAARGOS_1155]
ATGTTAGAGGTAATCATCAAAAAAATAAAAGAGTATAAAATTTTAGTTGGTTTAAGCCTGATTGGTTTGATCATAGCAGG
ATTTTTTCTGATGACTAGTAAATCTGCTAGACAATCTAATGTAGGAGATATTGCACAAGAGGCCACAAATGCAAAACTAG
AACGGAAAGAAACTTCAACTGAAACGAAGAAAAAACAACAGAAAGAAGAAACAGAATCTCAAAAGAATTTAGCGAGTGAA
GAATTGGAATTTTTAACTGTAGATGTTAAAGGTGCTGTTAAAAATCCAGGTATTTATCAATTAAAAAAAACAAGCCGAAT
CAATGATGCTATCCAAAAAGCGGGTGGACTAACGACAGACGCTGACAGCAAATCTATCAATTTGGCTCAAAAACTAACAG
ATGAGGCTGTGATTTATGTGGCAGCTATGGGTGAAAATGTAACAAATGCTGCAAGTAATAATGGACAAACTTTAACGACA
GATACCAATGGAACTGCGGCACAAAAAGGGAATAAGGTCAATCTAAATAAGGCCAATTTGTCTGATTTACAGTCTATTTC
TGGTATTGGACAAAAGCGCGCCCAAGATATTTTAGATTATCGTGAGTCAAACGGGAAATTTAATTCTGTTGATGACTTGA
AAAATGTATCAGGAGTAGGCGCCAAAACACTAGAAAAATTGAAAGAATATGTCACAGTGGATTAA

Domains

Predicted by InterproScan.

SLBB domain (SLBB)

(87-140)

Helix-hairpin-helix motif (HHH_3)

(169-232)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB I0SIU4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEA/celA/cilE Streptococcus mitis NCTC 12261

51.073

99.573

0.509
  comEA/celA/cilE Streptococcus pneumoniae TIGR4

50.644

99.573

0.504
  comEA/celA/cilE Streptococcus mitis SK321

50.644

99.573

0.504
  comEA/celA/cilE Streptococcus pneumoniae Rx1

50.215

99.573

0.5
  comEA/celA/cilE Streptococcus pneumoniae D39

50.215

99.573

0.5
  comEA/celA/cilE Streptococcus pneumoniae R6

50.215

99.573

0.5
  comEA Streptococcus thermophilus LMD-9

42.553

100

0.427
  comEA Lactococcus lactis subsp. cremoris KW2

37.768

99.573

0.376