Detailed information    

insolico Bioinformatically predicted

Overview

Name   comEC/celB   Type   Machinery gene
Locus tag   I6J12_RS03915 Genome accession   NZ_CP068060
Coordinates   823399..825627 (+) Length   742 a.a.
NCBI ID   WP_003034410.1    Uniprot ID   I0SIS4
Organism   Streptococcus anginosus strain FDAARGOS_1155     
Function   ssDNA transport into the cell (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 818399..830627
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  I6J12_RS03890 (I6J12_03890) rpmG 819261..819410 (+) 150 WP_003034401.1 50S ribosomal protein L33 -
  I6J12_RS03895 (I6J12_03895) secG 819450..819683 (+) 234 WP_003024744.1 preprotein translocase subunit SecG -
  I6J12_RS03900 (I6J12_03900) rnr 819774..822113 (+) 2340 WP_003034491.1 ribonuclease R -
  I6J12_RS03905 (I6J12_03905) smpB 822076..822543 (+) 468 WP_003034458.1 SsrA-binding protein SmpB -
  I6J12_RS03910 (I6J12_03910) comEA/celA/cilE 822711..823415 (+) 705 WP_003034448.1 helix-hairpin-helix domain-containing protein Machinery gene
  I6J12_RS03915 (I6J12_03915) comEC/celB 823399..825627 (+) 2229 WP_003034410.1 DNA internalization-related competence protein ComEC/Rec2 Machinery gene
  I6J12_RS03920 (I6J12_03920) - 825708..826400 (+) 693 WP_020999586.1 DUF805 domain-containing protein -
  I6J12_RS03925 (I6J12_03925) - 826905..827891 (+) 987 WP_003034384.1 Gfo/Idh/MocA family protein -
  I6J12_RS03930 (I6J12_03930) - 827913..828566 (+) 654 WP_003034489.1 uracil-DNA glycosylase -
  I6J12_RS03935 (I6J12_03935) - 828603..829073 (+) 471 WP_003034541.1 NUDIX hydrolase -
  I6J12_RS03940 (I6J12_03940) - 829086..830363 (+) 1278 WP_003034545.1 dihydroorotase -

Sequence

Protein


Download         Length: 742 a.a.        Molecular weight: 84993.86 Da        Isoelectric Point: 9.9333

>NTDB_id=526797 I6J12_RS03915 WP_003034410.1 823399..825627(+) (comEC/celB) [Streptococcus anginosus strain FDAARGOS_1155]
MSQWIKKFPIKPIYIAFLLVWLYFAIYQSSWLGWLGFIFLVIRLFRFYSPKECFMTFMILSCFVGFFFIRREMAERQANA
EPSPVKQIAVLPDTIKVNGDSLSFRGKTNGQTYQVYYKLKSKEEQLAFQNLSSLVILTVEGEFEIPEKKRNFAGFDYQSY
LKTQGIYRILKVDTILSSQDRISLHPFEWLSSWRRKALVFIKKHFPNPMSNYMTGLLFGALDTDFDEMNNLYSGLGIIHL
FALSGMQVGFFMEGFRKLLLRLGLTQEMVHKCQYPFSFFYAGMTGFSVSVVRSLVQKLLSQHGITKLDNFALTMMILSLI
MPSFLLTAGGVLSCAYAFVIGVIDFESLTSWRKIVVESSVISLGVLPILIFYFGEFQPWSILLTFVFSLIFDTMMLPGLT
LIFLSSPLIKLTQVNFLFEGLENSIRWLASVFGRPIVFGQPSPLLLIVMLLVLAILYDIRKNKKWVIFLSLLLSLLFFIN
KFPLQNEITMVDVGQGDSIFLRDWKGRNVLIDVGGREEIRTKEAWQKRATSSNAEKTLIPYLKSRGIDTIDALVLTNPNP
DYAGDVLEVAKKFAIKKIYISISSLSNADFLEKLRKINTFIHVVKQGDKLPIFDYHLQVLSGASKNDHSIVLYGQFFRTR
FLFASDLKEEGEAKLMQHYPKLKTDVLKVGQHGAKDSSSSKFLQQIEPTVALISVGKNNQSKQPSQDIIERFAQLPAKVY
RTDEQGAVKFSGWTNWRLEMVK

Nucleotide


Download         Length: 2229 bp        

>NTDB_id=526797 I6J12_RS03915 WP_003034410.1 823399..825627(+) (comEC/celB) [Streptococcus anginosus strain FDAARGOS_1155]
ATGTCACAGTGGATTAAAAAATTTCCGATTAAGCCGATTTACATTGCTTTCTTACTCGTCTGGTTATATTTTGCAATCTA
TCAAAGTAGCTGGTTAGGCTGGTTGGGTTTTATCTTTCTGGTGATTCGTCTTTTTCGCTTTTATTCACCAAAAGAATGTT
TCATGACCTTCATGATTCTCTCTTGTTTTGTTGGTTTTTTCTTTATTCGTAGGGAAATGGCAGAGCGGCAAGCAAATGCA
GAACCTTCTCCCGTAAAACAAATAGCAGTTCTACCTGACACGATTAAGGTAAATGGAGATTCACTTTCTTTCCGTGGTAA
AACAAATGGGCAGACTTATCAAGTTTACTACAAATTGAAATCAAAGGAAGAACAGTTGGCTTTTCAAAATCTCTCTAGTC
TGGTTATATTGACCGTTGAAGGGGAATTTGAAATCCCTGAGAAGAAGCGTAATTTTGCTGGTTTTGATTACCAATCCTAT
TTAAAAACGCAAGGGATTTATCGAATTTTAAAAGTGGATACCATTTTATCGAGCCAAGACAGAATCAGCTTGCACCCTTT
TGAGTGGCTTTCTAGCTGGCGAAGAAAAGCACTGGTATTTATCAAGAAGCATTTTCCAAATCCGATGAGTAATTACATGA
CAGGACTCTTATTTGGTGCCTTGGATACAGACTTCGATGAAATGAACAATCTTTACTCTGGCTTGGGGATTATTCATTTA
TTTGCGCTGTCTGGCATGCAAGTTGGCTTTTTTATGGAGGGTTTTCGTAAGTTGCTGTTAAGGTTGGGTCTTACACAGGA
AATGGTCCATAAATGCCAATATCCATTTTCTTTCTTCTATGCGGGAATGACTGGATTTTCAGTATCCGTTGTACGAAGCT
TAGTTCAGAAATTATTGTCGCAACATGGTATCACTAAGTTAGATAATTTTGCTTTAACGATGATGATATTGTCCTTGATT
ATGCCTTCCTTTCTTTTAACGGCAGGAGGAGTTCTCTCTTGCGCCTATGCTTTTGTTATTGGTGTGATAGATTTTGAAAG
TCTGACTTCTTGGCGAAAGATTGTTGTAGAGAGCAGTGTCATTTCGCTTGGTGTTTTACCGATTCTAATCTTTTATTTTG
GTGAATTTCAACCTTGGTCTATTTTGTTGACATTTGTTTTTTCACTAATTTTCGATACAATGATGCTGCCAGGCTTGACG
TTGATTTTTCTTTCTTCGCCTTTGATAAAGCTAACTCAGGTCAATTTTCTATTTGAAGGGTTAGAAAATAGCATTCGTTG
GCTAGCAAGTGTCTTTGGCAGACCAATCGTTTTTGGGCAACCCAGTCCGCTTTTGCTGATTGTTATGCTACTTGTACTGG
CTATTTTGTATGATATTAGAAAAAATAAAAAATGGGTAATATTTCTTAGTCTGCTTCTTTCATTACTCTTTTTCATAAAT
AAATTTCCCTTGCAAAATGAGATCACAATGGTTGATGTTGGGCAGGGAGATAGTATTTTTCTGAGAGACTGGAAAGGACG
AAATGTATTGATTGATGTTGGGGGACGTGAGGAAATTAGAACAAAAGAAGCTTGGCAAAAACGAGCGACTAGCTCAAATG
CAGAGAAAACTTTGATTCCTTACTTAAAAAGTCGTGGCATAGATACGATTGATGCTTTAGTCTTAACAAATCCTAATCCA
GATTATGCAGGAGATGTATTAGAAGTTGCTAAAAAATTTGCAATAAAGAAAATTTATATTTCCATAAGTAGTCTAAGCAA
TGCAGATTTTCTAGAGAAATTAAGGAAAATAAACACATTCATTCATGTTGTAAAACAAGGCGACAAACTTCCTATTTTTG
ATTATCATTTGCAAGTTCTTTCGGGTGCTAGCAAGAACGACCATTCGATCGTTTTATATGGTCAGTTTTTCCGTACAAGA
TTTTTATTTGCGAGCGACTTGAAAGAAGAGGGCGAAGCAAAGTTAATGCAGCATTATCCAAAGTTGAAAACAGATGTTTT
GAAAGTCGGACAGCATGGAGCCAAGGACTCATCAAGTTCAAAATTTTTACAACAAATAGAACCAACGGTCGCTCTCATTT
CTGTTGGGAAAAATAATCAATCTAAGCAACCAAGTCAAGATATAATAGAGCGATTTGCACAATTGCCTGCTAAGGTCTAT
CGGACAGATGAACAAGGGGCAGTTAAATTTTCAGGGTGGACAAACTGGCGATTAGAGATGGTCAAGTAA

Domains

Predicted by InterproScan.

Domain of unknown function (DUF4131) (DUF4131)

(30-175)

Metallo-beta-lactamase superfamily (Lactamase_B)

(492-593)

Competence protein (Competence)

(216-460)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB I0SIS4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEC/celB Streptococcus mitis SK321

55.615

100

0.561
  comEC/celB Streptococcus mitis NCTC 12261

54.886

100

0.553
  comEC/celB Streptococcus pneumoniae TIGR4

54.545

100

0.55
  comEC/celB Streptococcus pneumoniae Rx1

53.61

100

0.54
  comEC/celB Streptococcus pneumoniae D39

53.61

100

0.54
  comEC/celB Streptococcus pneumoniae R6

53.61

100

0.54
  comEC Lactococcus lactis subsp. cremoris KW2

47.248

100

0.474