Detailed information    

insolico Bioinformatically predicted

Overview


Name   comC/comC2   Type   Regulator
Locus tag   JJN14_RS09980 Genome accession   NZ_CP067992
Coordinates   2030120..2030242 (-) Length   40 a.a.
NCBI ID   WP_020902306.1    Uniprot ID   -
Organism   Streptococcus mitis strain S022-V7-A3     
Function   binding to ComD; induce autophosphorylation of ComD (predicted from homology)   
Competence regulation

Genomic Context


Location: 2025120..2035242
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  JJN14_RS09955 (JJN14_09955) - 2027248..2027790 (+) 543 WP_201058573.1 TetR/AcrR family transcriptional regulator -
  JJN14_RS09970 (JJN14_09970) comE 2028033..2028785 (-) 753 WP_000866073.1 competence system response regulator transcription factor ComE Regulator
  JJN14_RS09975 (JJN14_09975) comD 2028782..2030107 (-) 1326 WP_201058574.1 competence system sensor histidine kinase ComD Regulator
  JJN14_RS09980 (JJN14_09980) comC/comC2 2030120..2030242 (-) 123 WP_020902306.1 competence-stimulating peptide ComC Regulator
  JJN14_RS09990 (JJN14_09990) rlmH 2030524..2031003 (-) 480 WP_064276841.1 23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH -
  JJN14_RS09995 (JJN14_09995) htrA 2031187..2032368 (+) 1182 WP_153219714.1 S1C family serine protease Regulator
  JJN14_RS10000 (JJN14_10000) spo0J 2032426..2033184 (+) 759 WP_049509403.1 ParB/RepB/Spo0J family partition protein Regulator

Sequence


Protein


Download         Length: 40 a.a.        Molecular weight: 4746.60 Da        Isoelectric Point: 11.0565

>NTDB_id=526190 JJN14_RS09980 WP_020902306.1 2030120..2030242(-) (comC/comC2) [Streptococcus mitis strain S022-V7-A3]
MKNTVKLEQFVALKEKDLQEIRGGETRKTINSLLNLFKRR

Nucleotide


Download         Length: 123 bp        

>NTDB_id=526190 JJN14_RS09980 WP_020902306.1 2030120..2030242(-) (comC/comC2) [Streptococcus mitis strain S022-V7-A3]
ATGAAAAACACAGTTAAATTGGAACAGTTTGTAGCCTTGAAGGAAAAAGACTTGCAGGAGATTCGAGGTGGGGAAACTAG
AAAAACAATTAATAGTTTACTTAATCTCTTCAAAAGAAGATAA

Domains


Predicted by InterproScan.

(1-27)


Secondary structure


Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure


Source ID Structure

Transmembrane helices


Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.



Visualization of predicted probability:


Similar proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comC/comC2 Streptococcus pneumoniae A66

70

100

0.7

  comC/comC2 Streptococcus pneumoniae TIGR4

70

100

0.7

  comC Streptococcus mitis NCTC 12261

67.5

100

0.675

  comC Streptococcus mitis SK321

92.593

67.5

0.625

  comC/comC1 Streptococcus pneumoniae Rx1

88.889

67.5

0.6

  comC/comC1 Streptococcus pneumoniae R6

88.889

67.5

0.6

  comC/comC1 Streptococcus pneumoniae G54

88.889

67.5

0.6

  comC/comC1 Streptococcus pneumoniae D39

88.889

67.5

0.6