Detailed information    

insolico Bioinformatically predicted

Overview

Name   comD   Type   Regulator
Locus tag   JJN14_RS09975 Genome accession   NZ_CP067992
Coordinates   2028782..2030107 (-) Length   441 a.a.
NCBI ID   WP_201058574.1    Uniprot ID   -
Organism   Streptococcus mitis strain S022-V7-A3     
Function   phosphorylation of ComE (predicted from homology)   
Competence regulation

Genomic Context

Location: 2023782..2035107
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  JJN14_RS09950 (JJN14_09950) - 2024465..2027119 (-) 2655 WP_201058572.1 YhgE/Pip domain-containing protein -
  JJN14_RS09955 (JJN14_09955) - 2027248..2027790 (+) 543 WP_201058573.1 TetR/AcrR family transcriptional regulator -
  JJN14_RS09970 (JJN14_09970) comE 2028033..2028785 (-) 753 WP_000866073.1 competence system response regulator transcription factor ComE Regulator
  JJN14_RS09975 (JJN14_09975) comD 2028782..2030107 (-) 1326 WP_201058574.1 competence system sensor histidine kinase ComD Regulator
  JJN14_RS09980 (JJN14_09980) comC/comC2 2030120..2030242 (-) 123 WP_020902306.1 competence-stimulating peptide ComC Regulator
  JJN14_RS09990 (JJN14_09990) rlmH 2030524..2031003 (-) 480 WP_064276841.1 23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH -
  JJN14_RS09995 (JJN14_09995) htrA 2031187..2032368 (+) 1182 WP_153219714.1 S1C family serine protease Regulator
  JJN14_RS10000 (JJN14_10000) spo0J 2032426..2033184 (+) 759 WP_049509403.1 ParB/RepB/Spo0J family partition protein Regulator

Sequence

Protein


Download         Length: 441 a.a.        Molecular weight: 51195.04 Da        Isoelectric Point: 7.4362

>NTDB_id=526189 JJN14_RS09975 WP_201058574.1 2028782..2030107(-) (comD) [Streptococcus mitis strain S022-V7-A3]
MDFFLLVDLILYVFIISQSYRLICKRQIKTKELCFFGGYTLLVGTVLDLPFYLLYLEGLGIGTFLFPLMLYFYFKCIKQY
KRDRGLFLSLLLSLLYESTHTFLSVTFSSLTGDNFVLQYYGLFFLVVTVLTYVVIVTIIRYFHLELNYFDKDYLYPFLKK
VFFALLLLHIVSFISDMVSTIKHLNSFGSILSSIVFISLLLTFFAMNSHKEQMEKEIALKQKKFEQKHLQNYTDEIVALY
NEIRGFRHDYAGMLVSMQMAIDSGNLQEIDRVYTEVLVKANHKLRSDKYTYFDLNNIEDSALRSLVAQSIVYARNNGVEF
TLEVKDTITKLPIELLDLVRIMSVLLNNAVEGSADSYKKQMEVAVIKMETETVIVIQNSCKMTMTPSGDLFALGFSTKGR
NRGVGLNNVKELLDKYNNIILETEMEGSTFRQIIRFKREFE

Nucleotide


Download         Length: 1326 bp        

>NTDB_id=526189 JJN14_RS09975 WP_201058574.1 2028782..2030107(-) (comD) [Streptococcus mitis strain S022-V7-A3]
ATGGATTTTTTCTTATTAGTAGATTTGATATTATATGTTTTTATTATTAGTCAAAGTTACCGTTTAATTTGTAAAAGGCA
AATAAAAACAAAGGAATTATGCTTTTTTGGTGGTTATACATTACTAGTAGGAACAGTACTTGACCTTCCTTTTTATCTTC
TATACTTAGAGGGGTTAGGGATTGGAACATTTTTATTTCCTTTGATGCTATATTTCTATTTTAAATGTATTAAACAGTAT
AAGAGGGATAGAGGACTATTCCTAAGTTTACTACTATCTCTTTTATATGAGAGCACTCATACCTTTCTGTCTGTAACTTT
CTCCTCTCTAACAGGAGACAATTTTGTTTTACAATATTATGGCCTATTCTTTTTAGTTGTAACGGTGTTGACTTATGTCG
TTATCGTAACAATCATTCGTTATTTCCATTTGGAACTAAACTATTTTGACAAAGATTATCTCTATCCTTTCTTGAAAAAA
GTCTTTTTTGCTTTACTATTGCTACATATTGTATCTTTCATTTCAGATATGGTAAGTACGATTAAACATTTGAATAGTTT
TGGAAGTATTTTATCATCTATTGTCTTTATCTCTTTACTTTTGACTTTCTTTGCAATGAACTCTCATAAAGAACAAATGG
AGAAAGAGATTGCTTTGAAGCAGAAGAAATTTGAACAGAAACATTTACAGAATTATACAGACGAAATTGTTGCTTTGTAT
AATGAAATACGTGGGTTTAGACATGACTATGCTGGGATGCTTGTCAGCATGCAGATGGCAATTGACAGTGGTAATTTACA
GGAAATTGACAGAGTTTATACTGAAGTTTTGGTCAAAGCAAATCACAAACTGCGTTCAGATAAATACACTTACTTTGACT
TGAACAACATAGAAGATTCAGCTTTACGAAGTTTGGTTGCTCAGTCAATTGTCTATGCTCGAAATAATGGTGTAGAGTTT
ACACTGGAAGTAAAAGATACGATTACCAAGCTCCCAATTGAACTATTGGATTTGGTTCGTATCATGAGTGTTTTATTGAA
CAATGCTGTTGAAGGATCGGCTGATAGTTATAAAAAGCAGATGGAAGTAGCAGTTATTAAGATGGAAACTGAAACAGTTA
TTGTGATTCAGAATTCATGTAAAATGACGATGACTCCTTCAGGAGATCTATTTGCTTTAGGATTCTCCACTAAGGGAAGA
AATCGCGGAGTAGGATTAAATAATGTGAAAGAACTATTAGATAAGTACAACAATATTATTTTAGAAACAGAGATGGAAGG
CAGTACATTTAGACAAATCATTAGATTTAAGAGGGAATTTGAATGA

Domains

Predicted by InterproScan.

GHKL domain (HATPase_c_5)

(334-434)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comD Streptococcus mitis NCTC 12261

88.435

100

0.884
  comD Streptococcus mitis SK321

88.209

100

0.882
  comD/comD1 Streptococcus pneumoniae Rx1

87.982

100

0.88
  comD/comD1 Streptococcus pneumoniae D39

87.982

100

0.88
  comD/comD1 Streptococcus pneumoniae R6

87.982

100

0.88
  comD/comD2 Streptococcus pneumoniae TIGR4

87.755

100

0.878
  comD/comD2 Streptococcus gordonii strain NCTC7865

47.475

89.796

0.426
  comD/comD1 Streptococcus gordonii str. Challis substr. CH1

48.93

84.807

0.415