Detailed information
Bioinformatically predicted
Overview
| Name | clpP | Type | Regulator |
| Locus tag | JJN14_RS07185 | Genome accession | NZ_CP067992 |
| Coordinates | 1428859..1429449 (-) | Length | 196 a.a. |
| NCBI ID | WP_000613475.1 | Uniprot ID | F9HD24 |
| Organism | Streptococcus mitis strain S022-V7-A3 | ||
| Function | degradation of ComX; degradation of ComW (predicted from homology) Competence regulation |
||
Related MGE
Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.
Gene-MGE association summary
| MGE type | MGE coordinates | Gene coordinates | Relative position | Distance (bp) |
|---|---|---|---|---|
| ICE | 1407771..1476260 | 1428859..1429449 | within | 0 |
Gene organization within MGE regions
Location: 1407771..1476260
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| JJN14_RS07085 (JJN14_07085) | - | 1408177..1408860 (-) | 684 | WP_033686685.1 | amino acid ABC transporter permease | - |
| JJN14_RS07090 (JJN14_07090) | - | 1409051..1409281 (+) | 231 | WP_000443570.1 | DUF1797 family protein | - |
| JJN14_RS07095 (JJN14_07095) | clpE | 1409513..1411771 (+) | 2259 | WP_201058263.1 | ATP-dependent Clp protease ATP-binding subunit | Regulator |
| JJN14_RS07100 (JJN14_07100) | - | 1411907..1412359 (+) | 453 | WP_201058264.1 | NUDIX hydrolase | - |
| JJN14_RS07105 (JJN14_07105) | - | 1412418..1412717 (+) | 300 | WP_000767189.1 | DUF1827 family protein | - |
| JJN14_RS07110 (JJN14_07110) | - | 1412852..1413487 (+) | 636 | WP_201058265.1 | GNAT family N-acetyltransferase | - |
| JJN14_RS07115 (JJN14_07115) | metK | 1413571..1414761 (-) | 1191 | WP_201058266.1 | methionine adenosyltransferase | - |
| JJN14_RS07120 (JJN14_07120) | - | 1415122..1416465 (-) | 1344 | WP_061589833.1 | DEAD/DEAH box helicase | - |
| JJN14_RS07125 (JJN14_07125) | - | 1416758..1417573 (-) | 816 | WP_201058267.1 | endonuclease/exonuclease/phosphatase family protein | - |
| JJN14_RS07130 (JJN14_07130) | - | 1417625..1419808 (-) | 2184 | WP_201058268.1 | PTS transporter subunit IIBC | - |
| JJN14_RS07135 (JJN14_07135) | ftsX | 1419989..1420915 (-) | 927 | WP_042751472.1 | permease-like cell division protein FtsX | - |
| JJN14_RS07140 (JJN14_07140) | ftsE | 1420908..1421600 (-) | 693 | WP_004263501.1 | cell division ATP-binding protein FtsE | - |
| JJN14_RS07150 (JJN14_07150) | - | 1422822..1423478 (-) | 657 | WP_064276923.1 | CBS domain-containing protein | - |
| JJN14_RS07155 (JJN14_07155) | - | 1423846..1424556 (-) | 711 | WP_000062200.1 | ABC transporter ATP-binding protein | - |
| JJN14_RS07160 (JJN14_07160) | - | 1424556..1425320 (-) | 765 | WP_201058270.1 | ABC transporter ATP-binding protein | - |
| JJN14_RS07165 (JJN14_07165) | - | 1425320..1426276 (-) | 957 | WP_000662290.1 | branched-chain amino acid ABC transporter permease | - |
| JJN14_RS07170 (JJN14_07170) | - | 1426280..1427149 (-) | 870 | WP_000941421.1 | branched-chain amino acid ABC transporter permease | - |
| JJN14_RS07175 (JJN14_07175) | - | 1427265..1428425 (-) | 1161 | WP_070478656.1 | ABC transporter substrate-binding protein | - |
| JJN14_RS07180 (JJN14_07180) | - | 1428493..1428780 (-) | 288 | WP_049492230.1 | YlbG family protein | - |
| JJN14_RS07185 (JJN14_07185) | clpP | 1428859..1429449 (-) | 591 | WP_000613475.1 | ATP-dependent Clp protease proteolytic subunit ClpP | Regulator |
| JJN14_RS07190 (JJN14_07190) | upp | 1429623..1430252 (-) | 630 | WP_201058271.1 | uracil phosphoribosyltransferase | - |
| JJN14_RS07195 (JJN14_07195) | - | 1430341..1430808 (-) | 468 | WP_000136976.1 | deoxycytidylate deaminase | - |
| JJN14_RS07200 (JJN14_07200) | - | 1430827..1431384 (-) | 558 | WP_201058272.1 | TetR/AcrR family transcriptional regulator | - |
| JJN14_RS07205 (JJN14_07205) | - | 1431509..1432354 (+) | 846 | WP_201058273.1 | DegV family protein | - |
| JJN14_RS07210 (JJN14_07210) | - | 1432413..1433585 (+) | 1173 | WP_201058274.1 | NAD(P)/FAD-dependent oxidoreductase | - |
| JJN14_RS07215 (JJN14_07215) | - | 1433634..1434155 (+) | 522 | WP_201058275.1 | DUF1697 domain-containing protein | - |
| JJN14_RS07220 (JJN14_07220) | - | 1434197..1434937 (-) | 741 | WP_201058276.1 | MerR family transcriptional regulator | - |
| JJN14_RS07225 (JJN14_07225) | - | 1435278..1436618 (+) | 1341 | WP_201058277.1 | sodium-dependent transporter | - |
| JJN14_RS07230 (JJN14_07230) | manA | 1436659..1437603 (-) | 945 | WP_201058278.1 | mannose-6-phosphate isomerase, class I | - |
| JJN14_RS07235 (JJN14_07235) | - | 1437724..1439162 (-) | 1439 | Protein_1379 | 6-phospho-beta-glucosidase | - |
| JJN14_RS07240 (JJN14_07240) | - | 1439920..1441137 (-) | 1218 | WP_001291561.1 | tyrosine-type recombinase/integrase | - |
| JJN14_RS07245 (JJN14_07245) | - | 1441219..1441422 (-) | 204 | WP_000814511.1 | excisionase | - |
| JJN14_RS07250 (JJN14_07250) | - | 1441870..1442100 (-) | 231 | WP_000845144.1 | helix-turn-helix domain-containing protein | - |
| JJN14_RS07255 (JJN14_07255) | - | 1442097..1442519 (-) | 423 | WP_000804878.1 | RNA polymerase sigma factor | - |
| JJN14_RS07260 (JJN14_07260) | - | 1443051..1443404 (+) | 354 | WP_001227349.1 | helix-turn-helix transcriptional regulator | - |
| JJN14_RS07265 (JJN14_07265) | - | 1443462..1443647 (-) | 186 | WP_413926387.1 | cysteine-rich KTR domain-containing protein | - |
| JJN14_RS07270 (JJN14_07270) | tet(M) | 1443747..1445666 (-) | 1920 | WP_201058279.1 | tetracycline resistance ribosomal protection protein Tet(M) | - |
| JJN14_RS07275 (JJN14_07275) | - | 1445888..1446676 (-) | 789 | Protein_1387 | conjugal transfer protein | - |
| JJN14_RS10220 | - | 1446728..1446871 (-) | 144 | Protein_1388 | DUF961 family protein | - |
| JJN14_RS07280 (JJN14_07280) | - | 1447306..1447653 (-) | 348 | WP_201058281.1 | VOC family protein | - |
| JJN14_RS07285 (JJN14_07285) | spxB | 1447808..1449583 (-) | 1776 | WP_000191811.1 | pyruvate oxidase | - |
| JJN14_RS07290 (JJN14_07290) | - | 1449795..1452038 (-) | 2244 | WP_201058282.1 | heavy metal translocating P-type ATPase | - |
| JJN14_RS07295 (JJN14_07295) | - | 1452048..1452419 (-) | 372 | WP_000935055.1 | cupredoxin domain-containing protein | - |
| JJN14_RS07300 (JJN14_07300) | - | 1452430..1452825 (-) | 396 | WP_201058283.1 | CopY/TcrY family copper transport repressor | - |
| JJN14_RS07305 (JJN14_07305) | thiD | 1453191..1453982 (+) | 792 | WP_201058284.1 | bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase | - |
| JJN14_RS07310 (JJN14_07310) | - | 1454108..1455364 (+) | 1257 | WP_201058285.1 | ISL3 family transposase | - |
| JJN14_RS07315 (JJN14_07315) | thiE | 1455450..1456082 (-) | 633 | WP_201058286.1 | thiamine phosphate synthase | - |
| JJN14_RS07320 (JJN14_07320) | - | 1456075..1456878 (-) | 804 | WP_201058287.1 | hydroxyethylthiazole kinase | - |
| JJN14_RS07325 (JJN14_07325) | thiW | 1456878..1457402 (-) | 525 | WP_033685230.1 | energy coupling factor transporter S component ThiW | - |
| JJN14_RS07330 (JJN14_07330) | tenA | 1457407..1458099 (-) | 693 | WP_201058288.1 | thiaminase II | - |
| JJN14_RS07335 (JJN14_07335) | - | 1458110..1458760 (-) | 651 | WP_201058289.1 | energy-coupling factor transporter transmembrane component T | - |
| JJN14_RS07340 (JJN14_07340) | - | 1458762..1460147 (-) | 1386 | WP_201058290.1 | ATP-binding cassette domain-containing protein | - |
| JJN14_RS07345 (JJN14_07345) | - | 1460148..1460708 (-) | 561 | WP_201058291.1 | ECF transporter S component | - |
| JJN14_RS07350 (JJN14_07350) | thiE | 1461148..1461780 (-) | 633 | WP_201058292.1 | thiamine phosphate synthase | - |
| JJN14_RS07355 (JJN14_07355) | thiM | 1461782..1462564 (-) | 783 | WP_201058293.1 | hydroxyethylthiazole kinase | - |
| JJN14_RS07360 (JJN14_07360) | - | 1462840..1463508 (-) | 669 | WP_201058294.1 | TenA family protein | - |
| JJN14_RS07365 (JJN14_07365) | lctO | 1463963..1465099 (-) | 1137 | WP_000120714.1 | L-lactate oxidase | - |
| JJN14_RS07370 (JJN14_07370) | pyrE | 1465333..1465965 (-) | 633 | WP_201058295.1 | orotate phosphoribosyltransferase | - |
| JJN14_RS07375 (JJN14_07375) | pyrF | 1465999..1466700 (-) | 702 | WP_125386113.1 | orotidine-5'-phosphate decarboxylase | - |
| JJN14_RS07380 (JJN14_07380) | - | 1466933..1468186 (-) | 1254 | WP_201058296.1 | cell division protein FtsQ/DivIB | - |
| JJN14_RS07385 (JJN14_07385) | - | 1468196..1469254 (-) | 1059 | WP_201058297.1 | UDP-N-acetylglucosamine--N-acetylmuramyl- (pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase | - |
| JJN14_RS07390 (JJN14_07390) | murD | 1469256..1470608 (-) | 1353 | WP_125386116.1 | UDP-N-acetylmuramoyl-L-alanine--D-glutamate ligase | - |
| JJN14_RS07395 (JJN14_07395) | - | 1470723..1470977 (-) | 255 | WP_000262657.1 | DUF3165 family protein | - |
| JJN14_RS07400 (JJN14_07400) | typA | 1470997..1472838 (-) | 1842 | WP_000164111.1 | translational GTPase TypA | - |
| JJN14_RS07405 (JJN14_07405) | - | 1473000..1473725 (+) | 726 | WP_201058298.1 | 16S rRNA pseudouridine(516) synthase | - |
| JJN14_RS07410 (JJN14_07410) | - | 1473765..1473992 (-) | 228 | WP_201058299.1 | DUF4190 domain-containing protein | - |
| JJN14_RS07415 (JJN14_07415) | - | 1474158..1474385 (-) | 228 | WP_049492311.1 | hypothetical protein | - |
| JJN14_RS07420 (JJN14_07420) | - | 1474549..1474929 (-) | 381 | WP_201058300.1 | rhodanese-like domain-containing protein | - |
| JJN14_RS07425 (JJN14_07425) | - | 1474929..1475198 (-) | 270 | WP_020901947.1 | YqgQ family protein | - |
| JJN14_RS07430 (JJN14_07430) | - | 1475262..1476170 (+) | 909 | WP_084926873.1 | LysR family transcriptional regulator | - |
Sequence
Protein
Download Length: 196 a.a. Molecular weight: 21340.32 Da Isoelectric Point: 4.4910
>NTDB_id=526165 JJN14_RS07185 WP_000613475.1 1428859..1429449(-) (clpP) [Streptococcus mitis strain S022-V7-A3]
MIPVVIEQTSRGERSYDIYSRLLKDRIIMLTGPVEDNMANSVIAQLLFLDAQDSTKDIYLYVNTPGGSVSAGLAIVDTMN
FIKADVQTIVMGMAASMGTVIASSGAKGKRFMLPNAEYMIHQPMGGTGGGTQQTDMAIAAEHLLKTRNTLEKILAENSGQ
SIEKVHADAERDNWMSAQETLEYGFIDEIMANNSLN
MIPVVIEQTSRGERSYDIYSRLLKDRIIMLTGPVEDNMANSVIAQLLFLDAQDSTKDIYLYVNTPGGSVSAGLAIVDTMN
FIKADVQTIVMGMAASMGTVIASSGAKGKRFMLPNAEYMIHQPMGGTGGGTQQTDMAIAAEHLLKTRNTLEKILAENSGQ
SIEKVHADAERDNWMSAQETLEYGFIDEIMANNSLN
Nucleotide
Download Length: 591 bp
>NTDB_id=526165 JJN14_RS07185 WP_000613475.1 1428859..1429449(-) (clpP) [Streptococcus mitis strain S022-V7-A3]
ATGATTCCTGTAGTTATTGAACAAACAAGCCGTGGAGAACGTTCCTACGATATTTACTCACGTCTTCTCAAAGACCGCAT
CATCATGCTGACAGGCCCAGTTGAAGACAATATGGCCAACTCAGTTATTGCCCAATTGCTTTTCTTGGATGCCCAAGATA
GTACAAAAGATATTTACCTATATGTCAACACACCTGGTGGTTCCGTTTCAGCTGGTTTGGCAATCGTTGATACCATGAAC
TTTATCAAGGCAGATGTCCAAACCATCGTTATGGGAATGGCTGCATCTATGGGTACAGTCATCGCATCAAGTGGAGCAAA
AGGCAAACGTTTCATGCTTCCAAATGCTGAATACATGATCCACCAACCAATGGGTGGTACAGGTGGTGGTACTCAACAAA
CTGATATGGCTATCGCTGCAGAACACTTGCTTAAAACTCGTAACACCTTGGAAAAAATCTTGGCTGAAAATTCAGGTCAG
TCAATTGAAAAAGTCCATGCAGATGCAGAACGCGATAACTGGATGAGTGCTCAAGAAACACTTGAATATGGCTTTATTGA
TGAAATCATGGCCAACAATTCATTGAACTAA
ATGATTCCTGTAGTTATTGAACAAACAAGCCGTGGAGAACGTTCCTACGATATTTACTCACGTCTTCTCAAAGACCGCAT
CATCATGCTGACAGGCCCAGTTGAAGACAATATGGCCAACTCAGTTATTGCCCAATTGCTTTTCTTGGATGCCCAAGATA
GTACAAAAGATATTTACCTATATGTCAACACACCTGGTGGTTCCGTTTCAGCTGGTTTGGCAATCGTTGATACCATGAAC
TTTATCAAGGCAGATGTCCAAACCATCGTTATGGGAATGGCTGCATCTATGGGTACAGTCATCGCATCAAGTGGAGCAAA
AGGCAAACGTTTCATGCTTCCAAATGCTGAATACATGATCCACCAACCAATGGGTGGTACAGGTGGTGGTACTCAACAAA
CTGATATGGCTATCGCTGCAGAACACTTGCTTAAAACTCGTAACACCTTGGAAAAAATCTTGGCTGAAAATTCAGGTCAG
TCAATTGAAAAAGTCCATGCAGATGCAGAACGCGATAACTGGATGAGTGCTCAAGAAACACTTGAATATGGCTTTATTGA
TGAAATCATGGCCAACAATTCATTGAACTAA
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| clpP | Streptococcus pneumoniae Rx1 |
99.49 |
100 |
0.995 |
| clpP | Streptococcus pneumoniae D39 |
99.49 |
100 |
0.995 |
| clpP | Streptococcus pneumoniae R6 |
99.49 |
100 |
0.995 |
| clpP | Streptococcus pneumoniae TIGR4 |
99.49 |
100 |
0.995 |
| clpP | Streptococcus thermophilus LMG 18311 |
93.333 |
99.49 |
0.929 |
| clpP | Streptococcus thermophilus LMD-9 |
93.333 |
99.49 |
0.929 |
| clpP | Streptococcus pyogenes JRS4 |
91.282 |
99.49 |
0.908 |
| clpP | Streptococcus pyogenes MGAS315 |
91.282 |
99.49 |
0.908 |
| clpP | Streptococcus mutans UA159 |
86.224 |
100 |
0.862 |
| clpP | Lactococcus lactis subsp. lactis strain DGCC12653 |
85.128 |
99.49 |
0.847 |
| clpP | Lactococcus lactis subsp. cremoris KW2 |
84.615 |
99.49 |
0.842 |
| clpP | Bacillus subtilis subsp. subtilis str. 168 |
58.854 |
97.959 |
0.577 |
| clpP | Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819 |
58.031 |
98.469 |
0.571 |