Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilC   Type   Machinery gene
Locus tag   LPO_RS07195 Genome accession   NC_018139
Coordinates   1573832..1575052 (+) Length   406 a.a.
NCBI ID   WP_014841650.1    Uniprot ID   -
Organism   Legionella pneumophila subsp. pneumophila     
Function   assembly of type IV pilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1568832..1580052
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  LPO_RS07175 (LPO_1532) - 1569979..1570548 (-) 570 WP_014841648.1 hypoxanthine-guanine phosphoribosyltransferase -
  LPO_RS07180 (LPO_1533) - 1570591..1570917 (-) 327 WP_011213802.1 DUF1820 family protein -
  LPO_RS07185 (LPO_1534) - 1571100..1571843 (-) 744 WP_014841649.1 methyltransferase domain-containing protein -
  LPO_RS07190 (LPO_1535) pilB 1572102..1573826 (+) 1725 WP_010947251.1 type IV-A pilus assembly ATPase PilB Machinery gene
  LPO_RS07195 (LPO_1536) pilC 1573832..1575052 (+) 1221 WP_014841650.1 type II secretion system F family protein Machinery gene
  LPO_RS07200 (LPO_1537) pilD 1575097..1575960 (+) 864 WP_014841651.1 prepilin peptidase Machinery gene
  LPO_RS07205 (LPO_1538) - 1575974..1577179 (-) 1206 WP_014841652.1 cyclic nucleotide-binding domain-containing protein -
  LPO_RS07210 (LPO_1539) - 1577287..1577880 (-) 594 WP_011213808.1 hypothetical protein -
  LPO_RS07215 (LPO_1540) - 1577896..1578351 (-) 456 WP_014841654.1 hypothetical protein -
  LPO_RS07220 (LPO_1541) - 1578485..1579300 (+) 816 WP_014841655.1 pyruvate, water dikinase regulatory protein -

Sequence

Protein


Download         Length: 406 a.a.        Molecular weight: 44709.79 Da        Isoelectric Point: 9.5018

>NTDB_id=52129 LPO_RS07195 WP_014841650.1 1573832..1575052(+) (pilC) [Legionella pneumophila subsp. pneumophila]
MDKNSPPLLTFHYQGINKAGQKMEGDIQARSLAIAKADLRKQGIVTNKVVKKRNPLFDRKNKKITQADITVFSRQLATMI
ESGIPLVQAFDIVAKGQSNKRLKDLIETIKHDIETGLTLAESLIKHPLYFNELFCNLVDAGEKSGSLDIMLDKVATYKEK
IEIIKKKIKKALTYPIAVMVVALLVTAGLLIYVVPQFESLFKGFGADLPAMTRAVITMSEFMQTYWYIIFGALGGVVYSF
FYAKNHSLEFAQTIDRVMLKFPVIGPILEKAAIARFARTLSITFAAGLPLVEALKSVAGATGNIIYAKATDKIREEVATG
QQMFTAMENTHLFPNMVIQMVAIGEESGALEKMLSKVADFYEEEVNNAVDALSSLLEPIIMSILGILVGGLVVAMYLPIF
KLGSAV

Nucleotide


Download         Length: 1221 bp        

>NTDB_id=52129 LPO_RS07195 WP_014841650.1 1573832..1575052(+) (pilC) [Legionella pneumophila subsp. pneumophila]
ATGGATAAAAATAGCCCACCCCTATTAACCTTTCATTATCAAGGCATTAATAAAGCCGGTCAAAAAATGGAGGGTGATAT
TCAAGCCAGAAGCTTGGCAATAGCTAAAGCTGATTTGCGTAAGCAGGGGATTGTTACCAATAAAGTAGTAAAAAAAAGAA
ACCCTTTGTTTGATAGAAAAAATAAAAAAATCACACAAGCAGATATTACTGTGTTTAGCCGCCAATTAGCGACGATGATC
GAGTCAGGAATACCATTAGTGCAAGCATTTGATATTGTTGCCAAAGGACAAAGCAATAAAAGACTTAAAGACTTAATAGA
AACAATTAAGCACGATATCGAAACGGGGCTAACGCTGGCAGAATCCTTAATTAAACATCCACTCTATTTTAATGAATTAT
TTTGTAATCTTGTCGATGCTGGTGAAAAATCAGGCTCATTAGATATCATGCTTGACAAGGTTGCAACGTATAAAGAAAAA
ATTGAAATCATAAAAAAGAAAATAAAAAAAGCTCTCACTTACCCAATTGCTGTTATGGTTGTCGCACTTTTGGTTACTGC
GGGATTATTAATCTATGTGGTTCCTCAATTTGAATCATTGTTTAAAGGATTTGGAGCTGATTTGCCAGCGATGACTAGAG
CTGTGATCACTATGTCTGAATTTATGCAGACTTATTGGTATATTATTTTTGGAGCTTTGGGTGGGGTTGTCTATAGCTTT
TTTTATGCTAAAAATCATTCTTTGGAGTTTGCGCAAACCATTGACAGAGTGATGCTAAAATTCCCTGTAATTGGTCCTAT
TTTAGAGAAAGCAGCAATTGCTAGATTCGCGAGGACATTATCCATTACTTTTGCTGCTGGATTACCCCTGGTTGAAGCAT
TGAAATCTGTAGCTGGAGCGACCGGGAATATTATTTATGCCAAGGCGACTGATAAAATCAGAGAAGAAGTTGCAACAGGA
CAGCAAATGTTTACTGCTATGGAAAATACTCATTTATTTCCAAATATGGTAATTCAAATGGTAGCAATTGGTGAGGAATC
AGGTGCCCTTGAAAAAATGTTAAGCAAAGTGGCTGATTTTTATGAGGAAGAAGTAAATAATGCTGTAGATGCCCTGAGTA
GTTTATTGGAGCCGATAATTATGTCAATATTGGGTATACTGGTTGGGGGATTGGTGGTGGCTATGTATTTACCTATTTTC
AAACTGGGTTCTGCTGTTTAA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(276-398)

Type II secretion system (T2SS), protein F (T2SSF)

(72-195)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilC Legionella pneumophila strain ERS1305867

99.015

100

0.99
  pilC Acinetobacter baumannii D1279779

53.827

99.754

0.537
  pilC Pseudomonas stutzeri DSM 10701

53.96

99.507

0.537
  pilC Acinetobacter baylyi ADP1

52.593

99.754

0.525
  pilG Neisseria meningitidis 44/76-A

45.088

97.783

0.441
  pilG Neisseria gonorrhoeae MS11

44.836

97.783

0.438
  pilC Vibrio cholerae strain A1552

41.75

98.522

0.411
  pilC Vibrio campbellii strain DS40M4

38.916

100

0.389

Multiple sequence alignment