Detailed information    

insolico Bioinformatically predicted

Overview

Name   comEA/celA/cilE   Type   Machinery gene
Locus tag   SCIM_RS05070 Genome accession   NC_018073
Coordinates   1049398..1050102 (-) Length   234 a.a.
NCBI ID   WP_003076279.1    Uniprot ID   -
Organism   Streptococcus intermedius JTH08     
Function   dsDNA binding to the cell surface (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1044398..1055102
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SCIM_RS05055 (SCIM_0910) - 1044967..1045953 (-) 987 WP_003076968.1 Gfo/Idh/MocA family protein -
  SCIM_RS05060 (SCIM_0911) - 1046389..1047102 (-) 714 WP_003076424.1 DUF805 domain-containing protein -
  SCIM_RS05065 (SCIM_0912) comEC/celB 1047180..1049414 (-) 2235 WP_014829690.1 DNA internalization-related competence protein ComEC/Rec2 Machinery gene
  SCIM_RS05070 (SCIM_0913) comEA/celA/cilE 1049398..1050102 (-) 705 WP_003076279.1 helix-hairpin-helix domain-containing protein Machinery gene
  SCIM_RS05075 (SCIM_0914) smpB 1050270..1050737 (-) 468 WP_003076815.1 SsrA-binding protein SmpB -
  SCIM_RS05080 (SCIM_0915) rnr 1050700..1053039 (-) 2340 WP_003076716.1 ribonuclease R -
  SCIM_RS05085 (SCIM_0916) secG 1053130..1053363 (-) 234 WP_003024744.1 preprotein translocase subunit SecG -
  SCIM_RS09675 rpmG 1053403..1053552 (-) 150 WP_003034401.1 50S ribosomal protein L33 -
  SCIM_RS05090 (SCIM_0917) - 1053536..1054753 (-) 1218 WP_278043792.1 multidrug efflux MFS transporter -

Sequence

Protein


Download         Length: 234 a.a.        Molecular weight: 25420.77 Da        Isoelectric Point: 9.1090

>NTDB_id=51875 SCIM_RS05070 WP_003076279.1 1049398..1050102(-) (comEA/celA/cilE) [Streptococcus intermedius JTH08]
MLEVIVTKIKEYKILVALSLIGLIIAGFFMMTSKSARQSNVGDIAQETTNEKLERKETSTETKKKQQKEETESQKNLASE
EVEFLTVDVKGAVKNPGIYQLKKTSRINDAIQKAGGLTTDADSKSINLAQKLTDEAVIYVAAMGENVTNAASNNGQTLTK
DTNGTAAQKGNKVNLNKANLSDLQSISGIGQKRAQDILDYREANGKFNSVDDLKNVSGVGAKTLEKLKEYVTVD

Nucleotide


Download         Length: 705 bp        

>NTDB_id=51875 SCIM_RS05070 WP_003076279.1 1049398..1050102(-) (comEA/celA/cilE) [Streptococcus intermedius JTH08]
ATGTTAGAGGTAATCGTCACAAAAATCAAAGAGTATAAAATTTTAGTTGCTTTAAGCCTGATTGGTTTGATCATAGCAGG
ATTTTTTATGATGACTAGTAAATCTGCTAGACAATCTAATGTGGGAGATATTGCACAAGAGACCACAAATGAAAAACTAG
AACGGAAAGAAACTTCAACTGAAACGAAGAAAAAACAACAGAAAGAAGAAACAGAATCTCAAAAGAATTTAGCGAGTGAA
GAAGTGGAATTTTTAACTGTAGATGTTAAAGGTGCTGTTAAAAATCCAGGTATTTATCAATTAAAAAAAACGAGCCGTAT
CAATGATGCTATTCAAAAAGCGGGTGGACTAACAACAGACGCTGACAGCAAATCTATCAATTTGGCTCAAAAACTAACAG
ATGAGGCTGTGATTTATGTGGCAGCTATGGGTGAAAATGTAACAAATGCTGCAAGTAATAATGGACAAACTTTAACGAAA
GATACCAATGGAACTGCGGCACAAAAAGGGAATAAGGTCAATCTAAATAAGGCTAATTTGTCTGATTTACAGTCTATTTC
TGGTATCGGACAAAAGCGCGCCCAAGATATTTTAGATTATCGTGAGGCAAATGGAAAATTTAATTCTGTTGATGATCTTA
AAAATGTATCAGGAGTTGGTGCTAAAACATTAGAGAAATTGAAAGAATATGTCACAGTGGATTAA

Domains

Predicted by InterproScan.

SLBB domain (SLBB)

(87-140)

Helix-hairpin-helix motif (HHH_3)

(169-232)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEA/celA/cilE Streptococcus mitis SK321

49.789

100

0.504
  comEA/celA/cilE Streptococcus mitis NCTC 12261

50.215

99.573

0.5
  comEA/celA/cilE Streptococcus pneumoniae Rx1

49.785

99.573

0.496
  comEA/celA/cilE Streptococcus pneumoniae D39

49.785

99.573

0.496
  comEA/celA/cilE Streptococcus pneumoniae R6

49.785

99.573

0.496
  comEA/celA/cilE Streptococcus pneumoniae TIGR4

49.785

99.573

0.496
  comEA Streptococcus thermophilus LMD-9

43.162

100

0.432
  comEA Lactococcus lactis subsp. cremoris KW2

38.627

99.573

0.385

Multiple sequence alignment