Detailed information    

insolico Bioinformatically predicted

Overview

Name   comEC/celB   Type   Machinery gene
Locus tag   SCIM_RS05065 Genome accession   NC_018073
Coordinates   1047180..1049414 (-) Length   744 a.a.
NCBI ID   WP_014829690.1    Uniprot ID   -
Organism   Streptococcus intermedius JTH08     
Function   ssDNA transport into the cell (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1042180..1054414
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SCIM_RS05040 (SCIM_0907) - 1042506..1043780 (-) 1275 WP_003076495.1 dihydroorotase -
  SCIM_RS05045 (SCIM_0908) - 1043792..1044262 (-) 471 WP_003072602.1 NUDIX hydrolase -
  SCIM_RS05050 (SCIM_0909) - 1044289..1044942 (-) 654 WP_003072601.1 uracil-DNA glycosylase -
  SCIM_RS05055 (SCIM_0910) - 1044967..1045953 (-) 987 WP_003076968.1 Gfo/Idh/MocA family protein -
  SCIM_RS05060 (SCIM_0911) - 1046389..1047102 (-) 714 WP_003076424.1 DUF805 domain-containing protein -
  SCIM_RS05065 (SCIM_0912) comEC/celB 1047180..1049414 (-) 2235 WP_014829690.1 DNA internalization-related competence protein ComEC/Rec2 Machinery gene
  SCIM_RS05070 (SCIM_0913) comEA/celA/cilE 1049398..1050102 (-) 705 WP_003076279.1 helix-hairpin-helix domain-containing protein Machinery gene
  SCIM_RS05075 (SCIM_0914) smpB 1050270..1050737 (-) 468 WP_003076815.1 SsrA-binding protein SmpB -
  SCIM_RS05080 (SCIM_0915) rnr 1050700..1053039 (-) 2340 WP_003076716.1 ribonuclease R -
  SCIM_RS05085 (SCIM_0916) secG 1053130..1053363 (-) 234 WP_003024744.1 preprotein translocase subunit SecG -
  SCIM_RS09675 rpmG 1053403..1053552 (-) 150 WP_003034401.1 50S ribosomal protein L33 -

Sequence

Protein


Download         Length: 744 a.a.        Molecular weight: 85290.35 Da        Isoelectric Point: 10.2431

>NTDB_id=51874 SCIM_RS05065 WP_014829690.1 1047180..1049414(-) (comEC/celB) [Streptococcus intermedius JTH08]
MSQWIKIFPIKPIYIAFLLVWLYFAIYQSNWLAGVGLIFLLIRLSRIYSLKEWFTTLMILACFAVFFLVRRELANRKIKV
EAPPVRQVAVLPDTIKVNGDSLSFRGKAKGQTYQIYYKLKSKKEKLAFQNLSSLVTLTVEGEFESPEKQRNFSGFDYQAY
LKTQGIYRILKVDQILSSQDRVSLQPFEWLSSWRRKALVFIKRNFPNPMSNYMTGFLFGALDTDFGEMNNLYSSLGIIHL
FALSGMQVGFFMEGFRKSLLRLGLTQEIVHKCQYPFSFFYAGMTGFSVSVVRSLIQKLLSQHGITKLDNFALTIMVLSLI
MPSFLLTAGGVLSCAYAFIISVLDFKGLTPYKKIIIESIVISLGILPILIFYFGEFQPWSILLTFVFSLIFDIVMLPGLT
IIFLVSPFIKLTQVNFLFECLESSIRWLASMFSRPVVLGKPNPLLLIAMLLVLAILYDIRQNKKWLIFLSLFLSLLFFVA
KFPLQNEITMIDVGKGDSIFMRDWRGSTVLIDVGGREEIRKKESWQERISSSNAERTLIPYLKSRGVDTIDTLVLTNPNS
DYAGDVLEVAKKFSIKKIFISRSSLNDADFLNKLKETRAFVHVVKQGDKLPIFDHHLQVLSGTNKNDQSLVLYGQFFRTR
FLFMSNLTEEDEVKLMQLYPKLKTDVLKVGQHGSQNSSSSKFLQQVRPVIALISTGKNNSSKSLSQETIERFNRLNTKIY
RTDKQGAIKFSGWTTWQLETVQQP

Nucleotide


Download         Length: 2235 bp        

>NTDB_id=51874 SCIM_RS05065 WP_014829690.1 1047180..1049414(-) (comEC/celB) [Streptococcus intermedius JTH08]
ATGTCACAGTGGATTAAGATATTTCCGATCAAACCAATTTACATTGCTTTTTTACTTGTCTGGTTATATTTTGCAATCTA
TCAAAGTAATTGGTTGGCAGGAGTGGGATTGATCTTTCTGTTAATTCGTCTTTCCCGCATATATTCGCTAAAAGAATGGT
TTACAACTTTAATGATTCTCGCTTGTTTTGCTGTTTTTTTCCTTGTTCGTAGGGAACTGGCGAATCGGAAGATAAAAGTA
GAAGCTCCTCCTGTAAGACAAGTTGCGGTTTTACCTGATACAATTAAGGTAAATGGAGATTCGCTTTCTTTTCGTGGTAA
AGCAAAAGGACAGACATATCAAATTTACTACAAATTGAAATCAAAAAAAGAAAAGTTGGCTTTTCAAAATCTATCCAGCC
TTGTCACATTAACTGTTGAGGGGGAATTTGAATCTCCTGAAAAGCAGCGCAATTTTTCTGGTTTTGATTATCAAGCCTAT
CTAAAAACACAAGGGATTTATCGAATTTTAAAGGTGGATCAAATTTTGTCTAGTCAAGATAGGGTTAGCCTCCAACCGTT
TGAGTGGCTGTCTAGCTGGCGAAGAAAAGCATTGGTTTTCATTAAGAGAAATTTCCCGAATCCAATGAGCAATTATATGA
CAGGGTTTTTGTTCGGAGCTTTGGATACAGATTTTGGTGAAATGAATAACCTTTATTCGAGCTTGGGAATTATTCATTTA
TTTGCATTGTCTGGTATGCAAGTTGGTTTTTTTATGGAAGGGTTTCGTAAGTCACTGTTGAGATTGGGGCTTACGCAGGA
AATAGTTCATAAGTGTCAATATCCATTTTCTTTTTTTTATGCTGGAATGACAGGTTTTTCAGTATCCGTTGTACGGAGTT
TAATCCAGAAATTATTGTCACAACACGGCATTACTAAGTTAGATAATTTTGCTTTAACAATAATGGTGTTGTCCTTGATT
ATGCCCTCCTTTCTTTTAACAGCAGGAGGAGTACTTTCTTGTGCGTATGCTTTTATCATTAGCGTTTTAGATTTTAAAGG
CCTGACTCCTTATAAAAAGATTATTATAGAGAGTATTGTCATTTCGCTTGGCATTTTACCAATTTTAATCTTTTATTTCG
GAGAATTTCAGCCCTGGTCTATTTTATTGACATTTGTTTTTTCGTTGATTTTCGATATAGTGATGTTACCGGGGCTAACG
ATAATTTTTCTTGTTTCCCCTTTCATAAAACTCACTCAAGTTAATTTTCTATTTGAATGCTTAGAAAGTAGCATTCGCTG
GTTAGCAAGTATGTTTAGCAGACCAGTCGTTCTTGGCAAACCTAATCCACTTTTGCTAATCGCTATGTTGCTTGTATTAG
CTATCTTGTATGATATTCGGCAAAATAAAAAATGGCTGATATTTCTTAGTCTGTTTCTTTCATTACTCTTTTTTGTAGCT
AAATTTCCTTTACAAAATGAAATCACAATGATTGATGTCGGGAAGGGAGATAGTATTTTTATGCGAGACTGGAGAGGGAG
CACTGTATTGATTGATGTTGGCGGACGTGAAGAAATTAGAAAAAAAGAAAGTTGGCAAGAACGTATAAGTAGTTCAAACG
CAGAGAGAACGCTGATTCCATATCTTAAAAGTCGTGGTGTAGATACGATTGATACTTTAGTCTTAACAAATCCAAATTCA
GATTATGCAGGAGATGTATTAGAAGTTGCTAAAAAGTTTTCGATAAAGAAAATTTTTATTTCCAGAAGTAGTTTGAATGA
TGCAGACTTTTTAAATAAATTAAAGGAGACAAGGGCATTTGTTCATGTCGTAAAACAAGGAGACAAACTTCCTATTTTTG
ATCATCATTTGCAAGTTCTTTCTGGTACGAATAAGAATGATCAATCGCTAGTTTTATATGGTCAATTTTTTCGTACAAGG
TTTTTATTTATGAGCAATTTAACAGAAGAGGATGAAGTAAAGCTAATGCAACTTTATCCAAAACTAAAAACAGATGTCTT
GAAGGTTGGGCAACATGGATCCCAAAATTCATCAAGTTCTAAGTTCTTACAGCAAGTAAGACCAGTGATTGCCCTCATCT
CTACTGGGAAAAACAATTCATCCAAATCGCTAAGTCAAGAAACAATTGAGCGATTCAATCGATTAAATACAAAGATCTAT
CGAACAGATAAACAGGGGGCTATTAAGTTTTCGGGTTGGACAACATGGCAATTAGAAACTGTTCAGCAACCATAG

Domains

Predicted by InterproScan.

Domain of unknown function (DUF4131) (DUF4131)

(31-175)

Competence protein (Competence)

(218-461)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEC/celB Streptococcus mitis SK321

55.689

100

0.559
  comEC/celB Streptococcus mitis NCTC 12261

55.496

100

0.556
  comEC/celB Streptococcus pneumoniae TIGR4

54.485

100

0.547
  comEC/celB Streptococcus pneumoniae Rx1

53.949

100

0.542
  comEC/celB Streptococcus pneumoniae D39

53.949

100

0.542
  comEC/celB Streptococcus pneumoniae R6

53.949

100

0.542
  comEC Lactococcus lactis subsp. cremoris KW2

46.03

99.866

0.46

Multiple sequence alignment