Detailed information    

insolico Bioinformatically predicted

Overview

Name   micA   Type   Regulator
Locus tag   SCIM_RS03775 Genome accession   NC_018073
Coordinates   785735..786436 (+) Length   233 a.a.
NCBI ID   WP_003072980.1    Uniprot ID   A0A3R9KV56
Organism   Streptococcus intermedius JTH08     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 780735..791436
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SCIM_RS03755 (SCIM_0671) ccpA 781659..782663 (+) 1005 WP_003075707.1 catabolite control protein A Regulator
  SCIM_RS03760 (SCIM_0672) - 782756..783754 (+) 999 WP_003072984.1 glycosyltransferase family 4 protein -
  SCIM_RS03765 (SCIM_0673) - 783756..785069 (+) 1314 WP_003075701.1 glycosyltransferase family 4 protein -
  SCIM_RS03770 (SCIM_0674) - 785096..785437 (+) 342 WP_003075698.1 hypothetical protein -
  SCIM_RS03775 (SCIM_0675) micA 785735..786436 (+) 702 WP_003072980.1 response regulator YycF Regulator
  SCIM_RS03780 (SCIM_0676) micB 786429..787781 (+) 1353 WP_003072979.1 cell wall metabolism sensor histidine kinase VicK Regulator
  SCIM_RS03785 (SCIM_0677) vicX 787783..788586 (+) 804 WP_003075634.1 MBL fold metallo-hydrolase Regulator
  SCIM_RS03790 (SCIM_0678) - 788595..788954 (+) 360 WP_003072977.1 YbaN family protein -
  SCIM_RS03795 (SCIM_0679) rnc 789343..790041 (+) 699 WP_003072976.1 ribonuclease III -

Sequence

Protein


Download         Length: 233 a.a.        Molecular weight: 26851.80 Da        Isoelectric Point: 4.6824

>NTDB_id=51867 SCIM_RS03775 WP_003072980.1 785735..786436(+) (micA) [Streptococcus intermedius JTH08]
MKKILVVDDEKPISDIIKFNMVKEGYEVVTAFDGREALELFEAERPDILILDLMLPEIDGLEVARTIRKTSNVPIIVLSA
KDSEFDKVIGLEIGADDYMTKPFSNRELQARVKAILRRTDLTIENQEAEAAPTEIVIGDLQILTDAFVVKKHGEELDLTH
REFELLHHLATHIGQVMTREHLLETVWGYDYFGDVRTVDVTIRRLREKIEDIPSRPEYILTRRGVGYYMRNND

Nucleotide


Download         Length: 702 bp        

>NTDB_id=51867 SCIM_RS03775 WP_003072980.1 785735..786436(+) (micA) [Streptococcus intermedius JTH08]
ATGAAAAAAATATTAGTTGTAGATGATGAAAAACCAATCTCAGATATCATAAAATTTAACATGGTAAAAGAAGGTTATGA
GGTAGTGACAGCCTTCGATGGTCGTGAAGCGTTAGAGCTGTTTGAAGCAGAACGTCCAGATATTTTGATTTTGGATTTGA
TGTTGCCTGAAATAGATGGCTTAGAGGTAGCGCGAACGATTCGGAAAACGAGCAATGTACCAATCATCGTTCTGTCTGCT
AAAGATAGCGAATTTGATAAAGTCATTGGTCTCGAAATTGGCGCAGATGATTATATGACAAAGCCGTTTTCTAATCGTGA
GTTACAGGCGCGTGTCAAAGCTATTTTACGTCGTACAGATTTGACAATTGAAAATCAAGAAGCAGAAGCTGCTCCAACAG
AAATTGTGATTGGAGATTTGCAGATTTTGACGGATGCTTTTGTTGTGAAAAAGCATGGTGAAGAATTGGATTTAACACAC
CGTGAATTTGAATTACTACACCACCTAGCTACACATATTGGTCAAGTGATGACGCGTGAACACCTACTAGAAACAGTATG
GGGTTATGATTATTTTGGAGATGTGCGGACTGTTGATGTAACGATTCGCCGTTTGAGGGAAAAAATTGAAGATATTCCTA
GCCGCCCAGAGTATATTTTAACACGGCGTGGTGTTGGATATTATATGAGAAACAATGATTGA

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(153-228)

Response regulator receiver domain (Response_reg)

(4-112)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A3R9KV56

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  micA Streptococcus pneumoniae Cp1015

83.262

100

0.833
  vicR Streptococcus mutans UA159

79.237

100

0.803
  covR Streptococcus salivarius strain HSISS4

44.348

98.712

0.438
  covR Lactococcus lactis subsp. lactis strain DGCC12653

44.541

98.283

0.438
  scnR Streptococcus mutans UA159

36.052

100

0.361

Multiple sequence alignment