Detailed information    

insolico Bioinformatically predicted

Overview

Name   cinA   Type   Machinery gene
Locus tag   I6I02_RS10040 Genome accession   NZ_CP066093
Coordinates   2167999..2169264 (-) Length   421 a.a.
NCBI ID   WP_060972115.1    Uniprot ID   A0A6A8UKS0
Organism   Streptococcus salivarius strain FDAARGOS_1045     
Function   facilitate localization of RecA (predicted from homology)   
Homologous recombination

Genomic Context

Location: 2162999..2174264
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  I6I02_RS10030 (I6I02_10030) spx 2166252..2166650 (-) 399 WP_002886328.1 transcriptional regulator Spx -
  I6I02_RS10035 (I6I02_10035) recA 2166819..2167958 (-) 1140 WP_002889600.1 recombinase RecA Machinery gene
  I6I02_RS10040 (I6I02_10040) cinA 2167999..2169264 (-) 1266 WP_060972115.1 competence/damage-inducible protein A Machinery gene
  I6I02_RS10045 (I6I02_10045) - 2169361..2169915 (-) 555 WP_013989916.1 DNA-3-methyladenine glycosylase I -
  I6I02_RS10050 (I6I02_10050) ruvA 2169924..2170514 (-) 591 WP_013989915.1 Holliday junction branch migration protein RuvA -
  I6I02_RS10055 (I6I02_10055) - 2170672..2170893 (-) 222 WP_013989914.1 hypothetical protein -
  I6I02_RS10060 (I6I02_10060) mutL 2171024..2172967 (-) 1944 WP_198463551.1 DNA mismatch repair endonuclease MutL -
  I6I02_RS10065 (I6I02_10065) - 2173018..2173323 (-) 306 WP_037603797.1 hypothetical protein -
  I6I02_RS10070 (I6I02_10070) - 2173502..2173939 (+) 438 WP_198463552.1 LytTR family DNA-binding domain-containing protein -

Sequence

Protein


Download         Length: 421 a.a.        Molecular weight: 45529.76 Da        Isoelectric Point: 6.1862

>NTDB_id=517391 I6I02_RS10040 WP_060972115.1 2167999..2169264(-) (cinA) [Streptococcus salivarius strain FDAARGOS_1045]
MKAELIAVGTEILTGQITNTNAQFLSEKLAELGIDVYFHTAVGDNENRLLSVLEQASKRSDLVILCGGLGPTEDDLTKQT
LAKFLGKELVFDEEASKKLDSFFATRPKHTRTPNNERQAQIVEGAIPLQNPTGLAVGGVITTQGVTYVVLPGPPSELKPM
VNQELVPALTGNHASLYSRVLRFFGVGESQLVTILKDFIVNQTDPTIAPYAKVGEVTLRLSTKASSREEADQKLDVLEKQ
IRSTKTLDGKSLSDFIYGYGESNSLAFEAFRLLKNHGKTITAAESLTAGLFQASIADFSGASQVFKGGFVTYSIEEKSKM
LDIPLSQLEKHGVVSHFTAEKMAEGARAKTDSDYGIALTGVAGPDSLEGHPAGTVFIGIADRNQVRSIKVVIGGRSRSDV
RYISTLYAFNLVRQALLQETT

Nucleotide


Download         Length: 1266 bp        

>NTDB_id=517391 I6I02_RS10040 WP_060972115.1 2167999..2169264(-) (cinA) [Streptococcus salivarius strain FDAARGOS_1045]
ATGAAAGCTGAATTGATTGCAGTAGGAACCGAAATCCTAACCGGGCAAATCACCAATACCAATGCCCAATTTTTATCTGA
GAAACTAGCTGAATTAGGAATCGATGTGTATTTTCACACAGCAGTAGGAGACAATGAAAACCGCCTACTCTCAGTTCTAG
AACAAGCTAGTAAACGTAGTGATTTAGTCATACTTTGTGGAGGACTTGGTCCTACTGAGGATGACTTAACCAAGCAAACA
CTGGCTAAGTTTTTAGGCAAAGAACTCGTTTTTGATGAAGAGGCAAGTAAAAAATTGGACAGTTTCTTTGCTACTCGTCC
TAAACACACACGAACGCCTAATAATGAACGTCAAGCGCAAATTGTTGAGGGGGCTATCCCCTTGCAAAATCCTACAGGTC
TTGCAGTTGGAGGTGTCATTACTACTCAAGGGGTGACCTATGTAGTCCTACCTGGGCCACCAAGTGAACTTAAACCTATG
GTGAATCAGGAACTTGTTCCAGCACTTACTGGGAATCACGCAAGTCTTTATTCGAGAGTCCTAAGATTCTTTGGCGTTGG
AGAAAGTCAATTGGTGACTATTCTGAAGGATTTTATTGTTAACCAAACAGATCCAACCATAGCTCCATACGCTAAAGTGG
GAGAAGTAACACTTCGCTTGTCAACAAAGGCTTCTTCACGAGAAGAAGCGGATCAAAAACTAGATGTTTTAGAAAAACAA
ATTCGTTCTACTAAAACTCTAGATGGCAAATCCTTATCTGATTTTATTTATGGGTATGGAGAGTCTAATAGTTTAGCCTT
TGAAGCTTTTCGTTTGCTTAAGAACCATGGCAAGACTATCACTGCAGCTGAAAGCCTAACAGCAGGTTTATTTCAGGCTA
GTATTGCTGATTTTTCAGGAGCCTCACAAGTATTTAAAGGCGGCTTTGTTACTTACAGCATTGAAGAAAAATCTAAAATG
TTGGATATTCCCTTGTCGCAACTAGAAAAACATGGTGTTGTCAGTCATTTTACTGCAGAAAAAATGGCTGAAGGTGCCCG
AGCTAAAACAGATAGCGATTACGGAATTGCACTTACCGGAGTAGCTGGACCAGATTCATTAGAAGGACACCCAGCAGGTA
CAGTATTTATTGGTATTGCTGATAGGAATCAAGTAAGGTCAATCAAGGTTGTTATAGGTGGAAGAAGTCGTTCTGACGTT
AGATATATTAGTACCCTCTATGCCTTTAACCTAGTTCGCCAAGCCTTATTACAAGAGACAACTTGA

Domains

Predicted by InterproScan.

Probable molybdopterin binding domain (MoCF_biosynth)

(5-169)

Damage-inducible protein CinA KH domain (CinA_KH)

(178-243)

Competence-damaged protein (CinA)

(264-415)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A6A8UKS0

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cinA Streptococcus mitis SK321

74.94

99.525

0.746
  cinA Streptococcus mitis NCTC 12261

74.224

99.525

0.739
  cinA Streptococcus pneumoniae TIGR4

73.747

99.525

0.734
  cinA Streptococcus pneumoniae Rx1

73.508

99.525

0.732
  cinA Streptococcus pneumoniae R6

73.508

99.525

0.732
  cinA Streptococcus pneumoniae D39

73.27

99.525

0.729
  cinA Streptococcus mutans UA159

71.223

99.05

0.705
  cinA Streptococcus suis isolate S10

55.529

98.812

0.549
  cinA Bacillus subtilis subsp. subtilis str. 168

45.131

100

0.451