Detailed information NTG0517086

Bioinformatically predicted

Overview

• Name: cinA
• Type: Machinery gene
• Locus tag: I6H74_RS02090
• Genome accession: NZ_CP066069
• Coordinates: 391207..392478 (+)
• Length: 423 a.a.
• NCBI ID: WP_046177922.1
• Uniprot ID: -
• Organism: Streptococcus dysgalactiae strain FDAARGOS_1017
• Function: require for competence (predicted from homology) Unclear

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type	MGE coordinates	Gene coordinates	Relative position	Distance (bp)
IS/Tn	390189..391058	391207..392478	flank	149

Gene organization within MGE regions

Location: 390189..392478

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
I6H74_RS02085 (I6H74_02080)	-	390189..391007 (+)	819	Protein_359	ISAs1-like element IS1548 family transposase	-
I6H74_RS02090 (I6H74_02085)	cinA	391207..392478 (+)	1272	WP_046177922.1	competence/damage-inducible protein A	Machinery gene

Sequence

Protein

• Length: 423 a.a.
• Molecular weight: 45997.37 Da
• Isoelectric Point: 4.7637

>NTDB_id=517086 I6H74_RS02090 WP_046177922.1 391207..392478(+) (cinA) [Streptococcus dysgalactiae strain FDAARGOS_1017]
MKAELITVGTEILTGQIVNTNAQFLSEKMAELGIDVYFQTAVGDNEERLLSVIATASQRSDLVILCGGLGPTEDDLTKQT
LAKYLNRDLVFEEQASQKLDAFYASRKESSRTANNAKQAQIIAGSSPLQNRTGLAVGGLITVNEVTYVVLPGPPSELKPM
VNEELLPFLSTQSRKLYSRVLRFFGIGESQLVTVLSDLIENQTDPTIAPYAKTGEVTLRLSTKAENQTLADTKLDSLEAQ
LLSRKTPDNQSLSDFLYGYREDNSLAREVFELLVKYDKTITAAESLTAGLFQSTLASFSGASQVFNGGFVTYSMEEKARM
LGIPLEDLISHGVVSAYTAEKMAEQARLLTGADIGVSLTGVAGPDMLEEQPAGTVFIGLATQNKVESIKVLISGRSRSDV
RHIATLHAFNMVRKTLLKPENLL

Nucleotide

• Length: 1272 bp

>NTDB_id=517086 I6H74_RS02090 WP_046177922.1 391207..392478(+) (cinA) [Streptococcus dysgalactiae strain FDAARGOS_1017]
ATGAAAGCTGAACTGATTACAGTAGGTACCGAAATTTTGACTGGTCAAATTGTGAATACCAATGCTCAATTTCTGTCGGA
AAAAATGGCAGAGCTAGGTATTGATGTCTATTTTCAAACGGCTGTTGGGGATAACGAGGAGCGTTTACTTTCAGTGATTG
CAACTGCTAGTCAGCGGAGTGATTTGGTCATTTTATGCGGTGGTCTTGGCCCCACGGAAGATGATTTAACCAAGCAGACT
TTAGCAAAATATCTTAATAGAGATTTGGTCTTTGAAGAACAAGCTAGTCAAAAATTGGACGCTTTTTATGCTAGTCGTAA
AGAGTCGTCTCGAACGGCAAATAATGCTAAGCAGGCTCAAATCATTGCTGGTTCAAGCCCTCTGCAAAATAGAACAGGAC
TTGCAGTGGGTGGCTTAATCACTGTTAATGAGGTGACTTATGTTGTTTTACCCGGGCCGCCAAGTGAATTAAAACCTATG
GTTAATGAGGAACTGCTTCCTTTTTTGTCCACACAATCTCGCAAACTTTATTCGAGAGTTTTACGATTTTTTGGGATTGG
TGAGAGTCAGCTGGTGACGGTCTTATCAGACCTTATTGAGAATCAAACTGATCCTACTATTGCACCTTATGCCAAAACTG
GTGAAGTGACCCTTCGTTTATCAACGAAAGCTGAAAATCAAACATTAGCAGATACGAAATTAGATTCACTAGAAGCGCAG
CTATTGTCGCGAAAAACTCCTGACAACCAGTCGTTATCAGATTTTCTTTATGGCTATAGGGAGGATAATTCCTTAGCGCG
TGAGGTATTTGAGCTCTTAGTAAAATATGATAAGACAATTACTGCAGCAGAAAGTCTAACCGCGGGATTATTTCAGTCAA
CTTTGGCGAGTTTTTCAGGAGCTTCTCAAGTATTCAATGGAGGCTTTGTGACTTATAGCATGGAAGAAAAAGCGAGAATG
CTAGGCATTCCTTTAGAGGATTTGATATCGCATGGAGTTGTTAGTGCTTATACGGCCGAGAAGATGGCGGAGCAAGCAAG
GTTATTGACTGGTGCTGATATTGGGGTAAGTTTAACAGGTGTTGCCGGACCAGATATGTTGGAGGAACAGCCTGCAGGTA
CAGTTTTCATTGGCCTTGCCACTCAAAATAAGGTAGAATCAATAAAGGTTTTGATTAGCGGGCGAAGCCGTTCAGATGTG
CGTCATATTGCGACTTTACATGCTTTTAATATGGTCCGTAAAACTTTATTAAAACCTGAAAATTTGCTATAA

Domains

Predicted by InterproScan.

• Damage-inducible protein CinA KH domain (CinA_KH) (178-243)

• Competence-damaged protein (CinA) (263-416)

• Probable molybdopterin binding domain (MoCF_biosynth) (5-169)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
cinA	Streptococcus mutans UA159	72.577	100	0.726
cinA	Streptococcus mitis SK321	70.983	98.582	0.7
cinA	Streptococcus mitis NCTC 12261	70.024	98.582	0.69
cinA	Streptococcus pneumoniae TIGR4	69.784	98.582	0.688
cinA	Streptococcus pneumoniae Rx1	69.784	98.582	0.688
cinA	Streptococcus pneumoniae R6	69.784	98.582	0.688
cinA	Streptococcus pneumoniae D39	69.544	98.582	0.686
cinA	Streptococcus suis isolate S10	52.644	98.345	0.518
cinA	Bacillus subtilis subsp. subtilis str. 168	45.455	98.818	0.449