Detailed information NTG0516835

Bioinformatically predicted

Overview

• Name: comEA/celA/cilE
• Type: Machinery gene
• Locus tag: I6H72_RS02335
• Genome accession: NZ_CP066055
• Coordinates: 467617..468321 (-)
• Length: 234 a.a.
• NCBI ID: WP_150225670.1
• Uniprot ID: -
• Organism: Streptococcus constellatus strain FDAARGOS_1015
• Function: dsDNA binding to the cell surface (predicted from homology) DNA binding and uptake

Genomic Context

Location: 462617..473321

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
I6H72_RS02320 (I6H72_02320)	-	463176..464162 (-)	987	WP_198458221.1	Gfo/Idh/MocA family protein	-
I6H72_RS10190	-	464607..464747 (-)	141	WP_022525502.1	hypothetical protein	-
I6H72_RS10195	-	464838..465242 (-)	405	WP_006267075.1	DUF805 domain-containing protein	-
I6H72_RS02330 (I6H72_02330)	comEC/celB	465405..467633 (-)	2229	WP_020997762.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
I6H72_RS02335 (I6H72_02335)	comEA/celA/cilE	467617..468321 (-)	705	WP_150225670.1	helix-hairpin-helix domain-containing protein	Machinery gene
I6H72_RS02340 (I6H72_02340)	smpB	468489..468956 (-)	468	WP_006267184.1	SsrA-binding protein SmpB	-
I6H72_RS02345 (I6H72_02345)	rnr	469122..471258 (-)	2137	Protein_464	ribonuclease R	-
I6H72_RS02350 (I6H72_02350)	secG	471351..471584 (-)	234	WP_003024744.1	preprotein translocase subunit SecG	-
I6H72_RS02355 (I6H72_02355)	rpmG	471624..471773 (-)	150	WP_003024746.1	50S ribosomal protein L33	-
I6H72_RS02360 (I6H72_02360)	-	471757..472902 (-)	1146	WP_232619600.1	multidrug efflux MFS transporter	-

Sequence

Protein

• Length: 234 a.a.
• Molecular weight: 25361.75 Da
• Isoelectric Point: 8.7260

>NTDB_id=516835 I6H72_RS02335 WP_150225670.1 467617..468321(-) (comEA/celA/cilE) [Streptococcus constellatus strain FDAARGOS_1015]
MLEVIITKIKEYKILVCLSLIGLIIAGFFLMTSKSARQSNVGDIAQEATNAKLERKETSTETKKKQQKEETESQKNLASE
ELEFLTVDVKGAVKNPGIYQLKKTSRINDAIQKAGGLTTDADSKSINLAQKLTDEAVIYVAAMGENVTNAASNNGQTLTT
DTNGTAAQKGNKVNLNKANLSDLQSISGIGQKRAQDILDYREANGKFNSVDDLKNISGVGAKTLEKLKEYVTVD

Nucleotide

• Length: 705 bp

>NTDB_id=516835 I6H72_RS02335 WP_150225670.1 467617..468321(-) (comEA/celA/cilE) [Streptococcus constellatus strain FDAARGOS_1015]
ATGTTAGAGGTAATCATCACAAAAATAAAAGAGTATAAAATTTTAGTTTGTTTAAGCCTGATTGGTTTGATCATAGCAGG
ATTTTTTCTGATGACTAGTAAATCTGCTAGACAATCTAATGTAGGAGATATTGCACAAGAGGCCACAAATGCAAAACTAG
AACGGAAAGAAACTTCAACTGAAACGAAGAAAAAACAACAGAAAGAAGAAACAGAATCTCAAAAGAATTTAGCGAGTGAA
GAATTGGAATTTTTAACTGTAGATGTTAAAGGTGCTGTTAAAAATCCAGGTATTTATCAATTAAAAAAAACAAGCCGAAT
CAATGATGCTATCCAAAAAGCGGGTGGACTAACGACAGACGCTGACAGCAAATCTATCAATTTGGCTCAAAAACTAACAG
ATGAGGCTGTGATTTATGTGGCAGCTATGGGTGAAAATGTAACAAATGCTGCAAGTAATAATGGACAAACTTTAACGACA
GATACCAATGGAACTGCGGCACAAAAAGGGAATAAGGTCAATCTAAATAAGGCCAATTTGTCTGATTTACAGTCTATTTC
TGGTATTGGACAAAAGCGCGCCCAAGATATTTTAGATTATCGTGAGGCAAATGGAAAATTTAATTCTGTTGATGATCTTA
AAAATATATCAGGAGTTGGTGCTAAAACATTAGAGAAATTGAAAGAATATGTCACAGTGGATTAA

Domains

Predicted by InterproScan.

• SLBB domain (SLBB) (87-140)

• Helix-hairpin-helix motif (HHH_3) (169-232)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comEA/celA/cilE	Streptococcus mitis NCTC 12261	51.073	99.573	0.509
comEA/celA/cilE	Streptococcus pneumoniae TIGR4	50.644	99.573	0.504
comEA/celA/cilE	Streptococcus mitis SK321	50.644	99.573	0.504
comEA/celA/cilE	Streptococcus pneumoniae Rx1	50.215	99.573	0.5
comEA/celA/cilE	Streptococcus pneumoniae D39	50.215	99.573	0.5
comEA/celA/cilE	Streptococcus pneumoniae R6	50.215	99.573	0.5
comEA	Streptococcus thermophilus LMD-9	41.702	100	0.419
comEA	Lactococcus lactis subsp. cremoris KW2	37.339	99.573	0.372