Detailed information NTG0516834

Bioinformatically predicted

Overview

• Name: comEC/celB
• Type: Machinery gene
• Locus tag: I6H72_RS02330
• Genome accession: NZ_CP066055
• Coordinates: 465405..467633 (-)
• Length: 742 a.a.
• NCBI ID: WP_020997762.1
• Uniprot ID: -
• Organism: Streptococcus constellatus strain FDAARGOS_1015
• Function: ssDNA transport into the cell (predicted from homology) DNA binding and uptake

Genomic Context

Location: 460405..472633

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
I6H72_RS02305 (I6H72_02305)	-	460704..461981 (-)	1278	WP_198458219.1	dihydroorotase	-
I6H72_RS02310 (I6H72_02310)	-	461994..462464 (-)	471	WP_195674093.1	NUDIX hydrolase	-
I6H72_RS02315 (I6H72_02315)	-	462501..463154 (-)	654	WP_198458220.1	uracil-DNA glycosylase	-
I6H72_RS02320 (I6H72_02320)	-	463176..464162 (-)	987	WP_198458221.1	Gfo/Idh/MocA family protein	-
I6H72_RS10190	-	464607..464747 (-)	141	WP_022525502.1	hypothetical protein	-
I6H72_RS10195	-	464838..465242 (-)	405	WP_006267075.1	DUF805 domain-containing protein	-
I6H72_RS02330 (I6H72_02330)	comEC/celB	465405..467633 (-)	2229	WP_020997762.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
I6H72_RS02335 (I6H72_02335)	comEA/celA/cilE	467617..468321 (-)	705	WP_150225670.1	helix-hairpin-helix domain-containing protein	Machinery gene
I6H72_RS02340 (I6H72_02340)	smpB	468489..468956 (-)	468	WP_006267184.1	SsrA-binding protein SmpB	-
I6H72_RS02345 (I6H72_02345)	rnr	469122..471258 (-)	2137	Protein_464	ribonuclease R	-
I6H72_RS02350 (I6H72_02350)	secG	471351..471584 (-)	234	WP_003024744.1	preprotein translocase subunit SecG	-
I6H72_RS02355 (I6H72_02355)	rpmG	471624..471773 (-)	150	WP_003024746.1	50S ribosomal protein L33	-

Sequence

Protein

• Length: 742 a.a.
• Molecular weight: 85327.29 Da
• Isoelectric Point: 9.9939

>NTDB_id=516834 I6H72_RS02330 WP_020997762.1 465405..467633(-) (comEC/celB) [Streptococcus constellatus strain FDAARGOS_1015]
MSQWIKIFPIKPIYIAFLLVWLYFAIYQSSWLAWFCLIFLIVRLFVLYSPKKCFTTLMFLACFAAFFFVRREMAEWQTKA
EPSSVRQVAVLPDTIKVNGDSLSFRGKANGQTYQIYYKLKSKEEQLAFQNLSSLVTLTVEGEFESPEKQRNFSGFDYQVY
LKTQGIYRNLKVDQILSSQDRVSFQPFEWLSSWRRKALVFIKRNFPNPMNHYMTGLLFGALETDFDEMSDLYSSLGIIHL
FALSGMQVGFFMEGFRKLLLKLGLTKEMVHKCQYPFSFFYAGMTGFSVSVVRSLIQKLLSQHGITKLDNFALTIMVLSLL
MPSFLLTAGGVLSCAYAFVISVIDFESLTSWRKVVVESSIISLGVLPILIFYFGEFQPWSILLTFVFSLIFDIVMLPGLT
LIFLISPFIKLIQVNFLFEGLENSIRWIANVFGRPIVFGQPSSLLLVVMLLVLAILYDVRKNKKWVILLSLCLAILFFIT
KFPLQNEITMVDVGQGDSLFLRDWKGRNVLIDVGGREEIRTKESWQKRTTKSNAEKTLIPYLKSRGIDTIDTLILTNPNA
DYAGDVLKVVKKFAVKKIFISRSSLNDADFLNKLKETKTFVHVVKQGDKLPIFDHHLQVLSGTNKNDQSLVLYGQFFRTR
FLFMSNLTEEDEVKLMQLYPKLKTDVLKVGQHGAKNSSHSKFLQQIEPAVALISVGKNNQSKSPNQEMIERLNRLNAKIY
RTDERGAIKFSGWTKWQLETVQ

Nucleotide

• Length: 2229 bp

>NTDB_id=516834 I6H72_RS02330 WP_020997762.1 465405..467633(-) (comEC/celB) [Streptococcus constellatus strain FDAARGOS_1015]
ATGTCACAGTGGATTAAGATATTTCCGATTAAACCAATTTACATTGCTTTCTTACTTGTCTGGCTATATTTTGCAATCTA
TCAAAGTAGCTGGTTGGCTTGGTTTTGTCTTATTTTTCTAATAGTCCGTCTTTTTGTCCTTTATTCACCGAAAAAATGTT
TCACAACTTTAATGTTTCTCGCTTGTTTTGCTGCTTTTTTCTTTGTTCGTAGAGAAATGGCAGAGTGGCAAACAAAAGCA
GAACCTTCTTCTGTAAGACAAGTAGCAGTTCTACCTGACACGATTAAGGTAAATGGAGATTCGCTTTCTTTTCGCGGTAA
AGCAAATGGGCAGACTTATCAAATTTACTACAAATTGAAATCAAAAGAAGAACAGTTGGCTTTTCAAAATCTATCCAGTC
TTGTCACATTAACTGTTGAGGGGGAATTTGAATCTCCTGAAAAGCAGCGCAATTTTTCTGGTTTTGATTATCAAGTCTAT
CTAAAAACACAAGGGATTTATCGAAATTTAAAGGTGGATCAAATTTTGTCTAGTCAAGATAGGGTTAGCTTCCAACCGTT
TGAGTGGTTGTCTAGCTGGCGAAGAAAGGCATTGGTTTTCATTAAGAGAAATTTTCCAAATCCGATGAATCATTACATGA
CAGGGCTCTTATTTGGCGCATTAGAGACAGATTTTGATGAAATGAGTGATCTTTATTCTAGCTTGGGAATTATTCATTTA
TTTGCGTTATCTGGCATGCAAGTTGGCTTTTTTATGGAAGGATTTCGTAAGTTGCTTTTGAAGCTGGGACTTACGAAGGA
AATGGTTCATAAATGCCAATATCCGTTTTCTTTCTTTTATGCAGGAATGACTGGATTTTCAGTATCCGTTGTACGGAGCT
TAATTCAGAAATTATTGTCGCAACATGGTATCACTAAATTAGATAATTTTGCTTTAACAATAATGGTGTTGTCCTTGCTT
ATGCCATCTTTTCTTTTAACGGCAGGAGGAGTTCTCTCCTGTGCCTATGCTTTTGTTATTAGTGTTATAGATTTTGAAAG
TCTGACTTCTTGGAGAAAAGTTGTGGTAGAGAGTAGTATCATTTCACTTGGTGTTTTACCGATTCTAATCTTTTATTTTG
GAGAATTTCAACCTTGGTCTATTTTATTGACATTTGTTTTTTCACTAATTTTTGATATAGTGATGCTACCGGGTTTAACA
CTGATTTTTCTCATTTCACCTTTCATAAAGCTCATTCAAGTAAATTTTCTTTTTGAAGGCTTAGAAAATAGTATTCGTTG
GATAGCAAATGTCTTTGGCAGACCAATCGTTTTTGGGCAACCTAGCTCGCTTTTATTAGTTGTTATGCTGCTTGTACTGG
CTATTTTGTATGATGTTAGAAAAAATAAAAAATGGGTGATATTGCTCAGCTTGTGTCTTGCTATACTATTTTTTATAACT
AAATTTCCTTTGCAAAATGAGATCACAATGGTTGATGTTGGACAGGGAGATAGTCTTTTTTTGAGAGACTGGAAAGGTAG
AAATGTATTGATTGACGTTGGAGGACGTGAAGAAATTAGAACAAAAGAATCTTGGCAAAAACGAACAACTAAATCAAATG
CGGAGAAAACTTTGATTCCTTACCTAAAAAGTCGTGGTATAGATACGATTGATACTCTAATCTTAACAAATCCTAATGCA
GATTATGCGGGAGATGTATTAAAAGTGGTTAAAAAGTTTGCGGTAAAGAAAATTTTTATTTCCAGAAGTAGTTTGAATGA
TGCAGACTTTTTAAATAAATTAAAGGAGACAAAGACGTTTGTTCATGTCGTAAAACAAGGAGACAAACTTCCTATTTTTG
ATCATCATTTGCAAGTTCTTTCTGGTACGAATAAGAATGATCAATCGCTAGTTTTATATGGTCAATTTTTTCGTACAAGG
TTTTTATTTATGAGCAATTTAACAGAAGAGGATGAAGTAAAGCTAATGCAACTTTATCCAAAGCTAAAAACAGATGTCTT
GAAGGTTGGGCAACATGGAGCCAAAAATTCATCACATTCAAAATTTTTACAGCAAATAGAACCGGCAGTTGCACTCATTT
CTGTTGGGAAAAATAACCAATCCAAATCTCCGAATCAAGAAATGATAGAGCGATTGAATCGCTTAAATGCGAAGATTTAT
CGAACAGATGAACGAGGGGCGATCAAGTTTTCAGGATGGACAAAATGGCAATTAGAAACTGTTCAATAG

Domains

Predicted by InterproScan.

• Competence protein (Competence) (216-460)

• Metallo-beta-lactamase superfamily (Lactamase_B) (493-577)

• Domain of unknown function (DUF4131) (DUF4131) (30-175)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comEC/celB	Streptococcus mitis NCTC 12261	54.826	100	0.551
comEC/celB	Streptococcus mitis SK321	54.752	100	0.551
comEC/celB	Streptococcus pneumoniae TIGR4	53.949	100	0.543
comEC/celB	Streptococcus pneumoniae Rx1	53.146	100	0.535
comEC/celB	Streptococcus pneumoniae D39	53.146	100	0.535
comEC/celB	Streptococcus pneumoniae R6	53.146	100	0.535
comEC	Lactococcus lactis subsp. cremoris KW2	46.433	100	0.465