Detailed information    

insolico Bioinformatically predicted

Overview

Name   comX/comX2   Type   Regulator
Locus tag   I6I32_RS04245 Genome accession   NZ_CP066041
Coordinates   881834..882307 (-) Length   157 a.a.
NCBI ID   WP_001049305.1    Uniprot ID   K0ZQB4
Organism   Streptococcus oralis strain FDAARGOS_1075     
Function   activate transcription of late competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 876834..887307
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  I6I32_RS04245 (I6I32_04245) comX/comX2 881834..882307 (-) 474 WP_001049305.1 hypothetical protein Regulator
  I6I32_RS04250 (I6I32_04250) nusG 882428..882964 (-) 537 WP_000376732.1 transcription termination/antitermination protein NusG -
  I6I32_RS04255 (I6I32_04255) secE 883023..883199 (-) 177 WP_000505776.1 preprotein translocase subunit SecE -
  I6I32_RS04260 (I6I32_04260) rpmG 883209..883361 (-) 153 WP_001809375.1 50S ribosomal protein L33 -
  I6I32_RS04265 (I6I32_04265) pbp2a 883414..885609 (-) 2196 WP_198464992.1 penicillin-binding protein PBP2A -
  I6I32_RS04270 (I6I32_04270) - 885696..886571 (+) 876 WP_332836303.1 RluA family pseudouridine synthase -

Sequence

Protein


Download         Length: 157 a.a.        Molecular weight: 19280.16 Da        Isoelectric Point: 7.7801

>NTDB_id=516645 I6I32_RS04245 WP_001049305.1 881834..882307(-) (comX/comX2) [Streptococcus oralis strain FDAARGOS_1075]
MNLKDLYEESKGIVHKCRKDYHLHLWEKEDWDQEGMLCLYELVSCNPELLEGERHRLYVCFKTKFRNRILDYIRKQESHK
RRFDKEPYEEVSEISHRLGEKGLRLDDYYLFHELLKNYKSKQSMEKQELIDRLMGGEVFRGRKALLRELSLIFSEFR

Nucleotide


Download         Length: 474 bp        

>NTDB_id=516645 I6I32_RS04245 WP_001049305.1 881834..882307(-) (comX/comX2) [Streptococcus oralis strain FDAARGOS_1075]
ATGAATCTAAAAGATTTATATGAAGAAAGTAAGGGAATCGTCCATAAGTGTCGCAAAGATTATCATTTGCATCTGTGGGA
GAAAGAGGACTGGGATCAGGAAGGCATGTTATGTCTGTATGAGCTGGTGAGTTGCAACCCAGAGTTACTAGAGGGGGAGC
GCCATCGACTTTATGTCTGCTTTAAAACAAAGTTTAGAAATCGTATCCTAGATTACATCCGTAAACAGGAAAGCCACAAG
CGCCGTTTTGACAAAGAACCCTATGAAGAGGTGAGTGAGATTAGTCATCGTCTAGGAGAAAAAGGACTCAGGCTGGACGA
TTATTATCTCTTTCACGAACTTCTAAAGAATTACAAATCAAAGCAGAGTATGGAAAAACAAGAGTTAATAGACCGTCTAA
TGGGAGGAGAAGTCTTTAGAGGACGTAAAGCTCTCCTGAGAGAACTTTCCCTAATCTTTTCAGAATTTCGATAA

Domains


No domain identified.



Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB K0ZQB4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comX/comX2 Streptococcus pneumoniae Rx1

64.935

98.089

0.637
  comX/comX2 Streptococcus pneumoniae D39

64.935

98.089

0.637
  comX/comX1 Streptococcus pneumoniae D39

64.935

98.089

0.637
  comX/comX2 Streptococcus pneumoniae R6

64.935

98.089

0.637
  comX/comX1 Streptococcus pneumoniae R6

64.935

98.089

0.637
  comX/comX1 Streptococcus pneumoniae Rx1

64.935

98.089

0.637
  comX/comX2 Streptococcus pneumoniae TIGR4

64.286

98.089

0.631
  comX/comX1 Streptococcus pneumoniae TIGR4

64.286

98.089

0.631
  comX/sigX/comX2/sigX2 Streptococcus mitis SK321

64.286

98.089

0.631
  comX/sigX/comX1/sigX1 Streptococcus mitis SK321

63.636

98.089

0.624
  comX/sigX/comX2/sigX2 Streptococcus mitis NCTC 12261

62.987

98.089

0.618
  comX/sigX/comX1/sigX1 Streptococcus mitis NCTC 12261

62.987

98.089

0.618
  comR/comR2 Streptococcus gordonii str. Challis substr. CH1

53.846

99.363

0.535
  comR/comR1 Streptococcus gordonii str. Challis substr. CH1

53.846

99.363

0.535
  comX/sigX Streptococcus mutans UA159

46.711

96.815

0.452
  comX/sigX Streptococcus suis isolate S10

40.764

100

0.408
  comX/sigX Streptococcus suis D9

40.764

100

0.408
  comX/sigX Streptococcus suis P1/7

40.764

100

0.408
  comX/sigX/comX2/sigX2 Streptococcus pyogenes MGAS315

39.744

99.363

0.395
  comX/sigX/comX1/sigX1 Streptococcus pyogenes MGAS315

39.744

99.363

0.395
  comX/sigX/comX2/sigX2 Streptococcus pyogenes JRS4

39.744

99.363

0.395
  comX/sigX/comX1/sigX1 Streptococcus pyogenes JRS4

39.744

99.363

0.395
  comX/sigX/comX2/sigX2 Streptococcus pyogenes MGAS8232

39.744

99.363

0.395
  comX/sigX/comX1/sigX1 Streptococcus pyogenes MGAS8232

39.744

99.363

0.395
  comX Streptococcus thermophilus LMD-9

40

95.541

0.382
  comX/sigX Streptococcus salivarius strain HSISS4

40

95.541

0.382
  comX Streptococcus thermophilus LMG 18311

40

95.541

0.382
  comX Streptococcus salivarius SK126

40

95.541

0.382
  comX Streptococcus sobrinus strain NIDR 6715-7

41.958

91.083

0.382
  comX/sigX Streptococcus infantarius subsp. infantarius ATCC BAA-102

37.342

100

0.376