Detailed information NTG0516644

Bioinformatically predicted

Overview

• Name: ccpA
• Type: Regulator
• Locus tag: I6I32_RS04075
• Genome accession: NZ_CP066041
• Coordinates: 851652..852662 (-)
• Length: 336 a.a.
• NCBI ID: WP_084881331.1
• Uniprot ID: A0A1X1I3N6
• Organism: Streptococcus oralis strain FDAARGOS_1075
• Function: regulate comCDE transcription and transformation (predicted from homology) Competence regulation

Genomic Context

Location: 846652..857662

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
I6I32_RS04060 (I6I32_04060)	-	846688..848682 (-)	1995	WP_198464982.1	CAP domain-containing protein	-
I6I32_RS04065 (I6I32_04065)	-	849180..850571 (-)	1392	WP_198464983.1	Cof-type HAD-IIB family hydrolase	-
I6I32_RS04070 (I6I32_04070)	-	850637..851599 (+)	963	WP_061426607.1	asparaginase	-
I6I32_RS04075 (I6I32_04075)	ccpA	851652..852662 (-)	1011	WP_084881331.1	catabolite control protein A	Regulator
I6I32_RS04080 (I6I32_04080)	-	852868..853185 (+)	318	WP_000886045.1	DUF960 domain-containing protein	-
I6I32_RS04085 (I6I32_04085)	-	853236..854519 (-)	1284	WP_198464984.1	DUF308 domain-containing protein	-
I6I32_RS04090 (I6I32_04090)	folK	854512..855333 (-)	822	WP_000372502.1	2-amino-4-hydroxy-6- hydroxymethyldihydropteridine diphosphokinase	-
I6I32_RS04095 (I6I32_04095)	folE	855492..856046 (-)	555	WP_000380930.1	GTP cyclohydrolase I FolE	-
I6I32_RS04100 (I6I32_04100)	-	856027..857349 (-)	1323	WP_198464985.1	bifunctional folylpolyglutamate synthase/dihydrofolate synthase	-

Sequence

Protein

• Length: 336 a.a.
• Molecular weight: 37200.21 Da
• Isoelectric Point: 5.5004

>NTDB_id=516644 I6I32_RS04075 WP_084881331.1 851652..852662(-) (ccpA) [Streptococcus oralis strain FDAARGOS_1075]
MNTDDTVTIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEVIDRLDYRPNAVARGLASKKTTTVGVVIPNITNGYFS
TLAKGIDDIAEMYKYNIVLANSDEDDEKEVSVVNTLFSKQVDGIIFMGYHLTEKIRSEFSRSRTPVVLAGTVDVEHQLPS
VNIDYKQATIDAVSYLLKENEKIAFVSGPLVDDINGKVRLIGYKEALKKAGHSYSEGLVFESKYSYDDGYALAERLISSQ
ATAAVVTGDELAAGVLNGLADHGVSVPEDFEIITTDDSQIARFTRPNLTTIAQPLYDLGAISMRMLTKIMHKEELEEREV
LLPHGLTERRSTRKRK

Nucleotide

• Length: 1011 bp

>NTDB_id=516644 I6I32_RS04075 WP_084881331.1 851652..852662(-) (ccpA) [Streptococcus oralis strain FDAARGOS_1075]
ATGAACACAGATGATACAGTAACGATTTATGACGTCGCCCGTGAAGCAGGAGTTTCAATGGCAACAGTTAGCCGTGTCGT
TAATGGCAACAAGAATGTTAAAGAGAACACTCGAAAAAAAGTCCTAGAAGTGATTGATCGCTTGGACTATCGTCCAAATG
CGGTAGCACGTGGTTTGGCTAGCAAGAAAACAACGACAGTCGGAGTTGTGATTCCGAACATTACCAATGGTTATTTCTCA
ACGCTTGCTAAGGGGATTGACGACATTGCTGAAATGTACAAGTATAACATTGTCCTAGCAAATAGTGATGAGGATGATGA
AAAGGAAGTTTCAGTGGTTAACACTCTCTTTTCAAAACAAGTCGATGGGATTATCTTTATGGGCTATCACTTGACTGAAA
AGATTCGTTCAGAGTTTTCTCGTTCACGGACACCGGTTGTTCTTGCTGGTACTGTAGATGTAGAACACCAACTTCCAAGT
GTAAATATCGACTACAAACAAGCAACGATTGATGCTGTAAGCTACCTTCTCAAAGAAAACGAAAAGATTGCTTTTGTGAG
TGGACCACTCGTCGATGATATCAATGGCAAGGTTCGTTTGATCGGTTACAAGGAAGCCTTGAAAAAAGCAGGACATTCTT
ATAGTGAGGGATTGGTCTTTGAATCAAAATACAGCTATGACGATGGTTATGCCTTGGCAGAACGCTTGATTTCATCACAA
GCTACAGCCGCAGTTGTAACAGGTGATGAATTGGCGGCAGGTGTGTTGAATGGTTTGGCTGACCATGGTGTATCTGTGCC
AGAAGATTTTGAAATCATCACGACAGATGACTCTCAGATTGCACGATTCACTCGTCCAAACTTGACGACTATTGCCCAAC
CTCTTTATGACCTAGGTGCTATCAGCATGCGTATGTTGACTAAGATTATGCATAAGGAAGAGTTGGAAGAACGTGAAGTT
CTCTTGCCTCATGGTTTGACAGAACGCCGCTCTACACGAAAACGTAAATAG

Domains

Predicted by InterproScan.

• Periplasmic binding protein-like domain (Peripla_BP_3) (182-332)

• Bacterial regulatory proteins, lacI family (LacI) (8-53)

3D structure

• AlphaFold DB: A0A1X1I3N6

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ccpA	Streptococcus pneumoniae D39	94.643	100	0.946
ccpA	Streptococcus gordonii str. Challis substr. CH1	88.922	99.405	0.884
ccpA	Lactococcus lactis subsp. lactis strain DGCC12653	58.006	98.512	0.571