Detailed information    

insolico Bioinformatically predicted

Overview

Name   comR   Type   Regulator
Locus tag   STCNRZ1575_RS01515 Genome accession   NZ_CP065490
Coordinates   271581..272480 (+) Length   299 a.a.
NCBI ID   WP_179974221.1    Uniprot ID   -
Organism   Streptococcus thermophilus strain CNRZ1575     
Function   activate transcription of comX; activate transcription of comS (predicted from homology)   
Competence regulation

Genomic Context

Location: 266581..277480
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  STCNRZ1575_RS01495 (STCNRZ1575_01510) trkA 267717..269066 (-) 1350 WP_011225444.1 Trk system potassium transporter TrkA -
  STCNRZ1575_RS01500 (STCNRZ1575_01515) - 269355..269864 (+) 510 WP_011680717.1 tRNA (cytidine(34)-2'-O)-methyltransferase -
  STCNRZ1575_RS01505 (STCNRZ1575_01520) - 270176..270733 (+) 558 WP_002949523.1 ECF transporter S component -
  STCNRZ1575_RS01510 (STCNRZ1575_01525) - 270736..271386 (+) 651 WP_095559229.1 phosphatase PAP2 family protein -
  STCNRZ1575_RS01515 (STCNRZ1575_01530) comR 271581..272480 (+) 900 WP_179974221.1 helix-turn-helix domain-containing protein Regulator
  STCNRZ1575_RS01520 - 272718..273014 (+) 297 Protein_233 cysteine peptidase family C39 domain-containing protein -
  STCNRZ1575_RS01525 comA 273177..273413 (+) 237 WP_260214320.1 ABC transporter transmembrane domain-containing protein Regulator
  STCNRZ1575_RS01530 - 273403..273897 (+) 495 Protein_235 ABC transporter transmembrane domain-containing protein -
  STCNRZ1575_RS01535 comA 273919..274128 (+) 210 WP_002946147.1 hypothetical protein Regulator
  STCNRZ1575_RS01540 (STCNRZ1575_01555) - 274183..274751 (+) 569 Protein_237 ATP-binding cassette domain-containing protein -
  STCNRZ1575_RS01545 (STCNRZ1575_01560) - 274859..275176 (+) 318 WP_011225454.1 DUF805 domain-containing protein -
  STCNRZ1575_RS01550 - 275139..275423 (-) 285 WP_014727318.1 hypothetical protein -
  STCNRZ1575_RS01555 - 275663..276559 (-) 897 WP_260214319.1 urease cluster protein -
  STCNRZ1575_RS01560 (STCNRZ1575_01570) - 276964..277479 (+) 516 WP_002949547.1 AmiS/UreI family transporter -

Sequence

Protein


Download         Length: 299 a.a.        Molecular weight: 35302.78 Da        Isoelectric Point: 5.2218

>NTDB_id=510762 STCNRZ1575_RS01515 WP_179974221.1 271581..272480(+) (comR) [Streptococcus thermophilus strain CNRZ1575]
MNIKDSIGLRIKTERERQQMSREVLCLDGAELTVRQLIRIEKGESLPSLDRLSYIAKRLGKSMTELLDQDNITIPDEYYE
MKNRLIKFPTYRNPDRIKSKLTLIEEVYEKFFDILPEEELLTLDILENILSFTSWQESPKVEEIYEDLFEQVKRKRKFST
NDLLVIDYYFFHLYGRKQYDKKLFERIIKRVLNQEIWTDDVYNIVLFNDLMAIAALKIFHNSFSDFLTVVDKALAVIEKS
QLYSYKPSVFVLKAKYELLHKENKKEAAENYDKAIMFASVLEDSVLEESIKAGKLADGL

Nucleotide


Download         Length: 900 bp        

>NTDB_id=510762 STCNRZ1575_RS01515 WP_179974221.1 271581..272480(+) (comR) [Streptococcus thermophilus strain CNRZ1575]
TTGAACATAAAAGACAGCATTGGACTAAGAATCAAAACTGAGCGTGAACGCCAACAGATGTCACGTGAAGTGCTATGTTT
AGATGGTGCGGAATTGACTGTTCGCCAGTTAATTCGTATTGAAAAGGGGGAGTCTCTCCCGTCTTTAGATAGATTATCGT
ATATTGCTAAACGTTTAGGAAAAAGTATGACAGAGTTATTGGATCAAGACAATATTACCATTCCTGACGAATATTATGAA
ATGAAGAATCGTTTGATTAAGTTTCCAACGTACAGAAATCCTGACAGAATAAAGTCTAAACTTACTTTGATTGAGGAAGT
CTATGAGAAATTTTTTGATATTCTTCCAGAAGAAGAATTATTAACTCTAGACATTCTCGAAAATATATTGAGTTTTACTA
GCTGGCAGGAGAGTCCAAAAGTTGAGGAGATATATGAAGACTTATTTGAACAAGTCAAAAGGAAGAGGAAATTCTCAACT
AACGATTTATTAGTCATTGACTATTATTTCTTTCATCTTTATGGGAGAAAACAGTATGACAAAAAACTATTTGAAAGAAT
TATAAAGAGAGTGTTAAATCAGGAAATTTGGACAGATGATGTTTACAATATTGTTTTATTTAATGATTTGATGGCTATTG
CTGCTTTAAAGATTTTTCACAATTCCTTCTCAGACTTCTTAACAGTTGTGGATAAAGCCTTGGCTGTCATAGAAAAATCA
CAATTATATAGCTACAAACCTAGTGTTTTTGTACTTAAGGCTAAATATGAACTTCTGCATAAAGAAAACAAGAAAGAGGC
TGCAGAGAATTATGATAAGGCCATAATGTTTGCTTCCGTTTTGGAAGACTCGGTTTTAGAGGAAAGTATAAAGGCAGGAA
AATTGGCAGATGGTTTATAG

Domains

Predicted by InterproScan.

Helix-turn-helix (HTH_3)

(11-66)

ComR tetratricopeptide (ComR_TPR)

(75-292)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comR Streptococcus thermophilus LMG 18311

99.666

100

0.997
  comR Streptococcus thermophilus LMD-9

98.997

100

0.99
  comR Streptococcus salivarius strain HSISS4

94.983

100

0.95
  comR Streptococcus salivarius SK126

94.314

100

0.943
  comR/comR1 Streptococcus sobrinus strain NIDR 6715-7

42.14

100

0.421
  comR/comR2 Streptococcus sobrinus strain NIDR 6715-7

42.14

100

0.421