Detailed information    

insolico Bioinformatically predicted

Overview

Name   cinA   Type   Machinery gene
Locus tag   STAVA1121_RS00360 Genome accession   NZ_CP065488
Coordinates   61909..63180 (+) Length   423 a.a.
NCBI ID   WP_347131309.1    Uniprot ID   -
Organism   Streptococcus thermophilus strain AVA1121     
Function   facilitate localization of RecA (predicted from homology)   
Homologous recombination

Genomic Context

Location: 56909..68180
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  STAVA1121_RS00330 (STAVA1121_00325) - 57244..57637 (-) 394 Protein_44 LytTR family DNA-binding domain-containing protein -
  STAVA1121_RS00335 (STAVA1121_00330) - 57861..58166 (+) 306 WP_347131308.1 hypothetical protein -
  STAVA1121_RS00340 (STAVA1121_00335) mutL 58218..60160 (+) 1943 Protein_46 DNA mismatch repair endonuclease MutL -
  STAVA1121_RS00345 - 60290..60510 (+) 221 Protein_47 hypothetical protein -
  STAVA1121_RS00350 (STAVA1121_00340) ruvA 60662..61252 (+) 591 WP_002949053.1 Holliday junction branch migration protein RuvA -
  STAVA1121_RS00355 (STAVA1121_00345) - 61259..61813 (+) 555 Protein_49 DNA-3-methyladenine glycosylase I -
  STAVA1121_RS00360 (STAVA1121_00350) cinA 61909..63180 (+) 1272 WP_347131309.1 competence/damage-inducible protein A Machinery gene
  STAVA1121_RS00365 (STAVA1121_00355) recA 63216..64355 (+) 1140 WP_011680606.1 recombinase RecA Machinery gene
  STAVA1121_RS00370 (STAVA1121_00360) spx 64532..64929 (+) 398 Protein_52 transcriptional regulator Spx -

Sequence

Protein


Download         Length: 423 a.a.        Molecular weight: 45983.35 Da        Isoelectric Point: 5.0948

>NTDB_id=510637 STAVA1121_RS00360 WP_347131309.1 61909..63180(+) (cinA) [Streptococcus thermophilus strain AVA1121]
MKAELIAVGTEILTGQITNTNAQFLSEKLAELGIDVYFHTAVGDNENRLLSVLDQSSKRSDLVILCGGLGPTEDDLTKQT
LAKFLGKELIFDEEASKKLDSFFATRPKHTRTPNNERQAQIVEGAVPLQNLTGLAVGGIITVEGVTYVVLPGPPSELKPM
VNQELIPALTENHTTLYSRVLRFFGVGESQLVTIIKDLIVNQTDPTIAPYAKVGEVTLRLSTKASSQEEANRKLDVLEEQ
IRSTKTLDGKSLSDLIYGYGESNSLAYEVFYLLKKYGKTITAAESLTAGLFQASVADFPGASQVFKGGFVTYSMEEKAKM
LDIPLSKLEEHGVVSHFTAEKMAEGARVKTDSDYGIALTGVAGPDALEGHQAGTVFIGIADRNQVRSIKVVIGGRSRSDV
RYISTLYAFNLVRQALLQEDNSI

Nucleotide


Download         Length: 1272 bp        

>NTDB_id=510637 STAVA1121_RS00360 WP_347131309.1 61909..63180(+) (cinA) [Streptococcus thermophilus strain AVA1121]
ATGAAAGCTGAATTGATTGCAGTAGGAACTGAAATTCTTACAGGGCAAATCACCAATACCAATGCCCAATTTTTATCTGA
AAAACTAGCTGAATTAGGAATTGACGTGTATTTTCACACAGCGGTAGGAGACAATGAAAACCGTCTACTTTCAGTCTTAG
ACCAGTCTAGTAAACGTAGCGATTTAGTCATACTCTGTGGAGGACTTGGCCCTACTGAGGATGACTTAACCAAACAAACA
TTGGCTAAGTTTTTAGGCAAAGAACTCATTTTTGATGAGGAGGCAAGTAAAAAACTGGATAGTTTCTTTGCTACTCGTCC
TAAACATACACGAACGCCTAATAATGAACGCCAAGCGCAAATTGTTGAGGGGGCTGTCCCCTTGCAAAATCTCACAGGCC
TGGCAGTTGGAGGAATTATTACTGTTGAAGGAGTGACCTATGTTGTCTTGCCTGGTCCGCCAAGTGAACTCAAACCTATG
GTGAACCAAGAGCTTATTCCAGCTCTTACAGAGAATCATACTACGCTTTATTCTAGAGTCCTAAGGTTTTTTGGTGTTGG
AGAAAGTCAATTGGTGACTATTATTAAAGATCTCATTGTTAACCAAACAGACCCAACCATTGCGCCCTATGCTAAAGTGG
GAGAAGTGACCCTTCGCTTATCAACAAAGGCATCGTCGCAAGAAGAAGCGAATCGAAAACTAGATGTTTTAGAAGAACAA
ATTCGTTCTACTAAAACTCTAGATGGAAAAAGCTTGTCTGATCTCATCTATGGATATGGAGAATCAAATAGCTTAGCTTA
TGAAGTGTTCTATTTGCTTAAGAAATATGGCAAAACTATTACTGCAGCTGAAAGTTTAACAGCTGGCTTATTTCAAGCTA
GTGTTGCTGATTTTCCTGGAGCTTCACAAGTATTCAAGGGTGGTTTTGTCACCTATAGCATGGAAGAAAAAGCTAAAATG
TTGGATATTCCCTTATCTAAATTAGAAGAGCATGGTGTTGTTAGTCATTTTACAGCAGAAAAAATGGCTGAGGGTGCCCG
AGTTAAGACAGATAGTGATTACGGAATTGCGCTTACTGGAGTAGCAGGACCAGATGCTTTGGAAGGGCATCAAGCAGGTA
CAGTCTTTATTGGTATTGCCGATAGAAACCAAGTGCGGTCAATTAAGGTTGTTATAGGTGGAAGAAGTCGATCTGATGTT
AGATATATCAGTACACTCTATGCCTTTAACCTAGTTCGCCAAGCTTTATTACAAGAGGACAACTCAATTTAA

Domains

Predicted by InterproScan.

Competence-damaged protein (CinA)

(264-415)

Damage-inducible protein CinA KH domain (CinA_KH)

(178-243)

Probable molybdopterin binding domain (MoCF_biosynth)

(5-170)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cinA Streptococcus mitis SK321

75.179

99.054

0.745
  cinA Streptococcus mitis NCTC 12261

73.986

99.054

0.733
  cinA Streptococcus pneumoniae TIGR4

72.792

99.054

0.721
  cinA Streptococcus pneumoniae Rx1

72.554

99.054

0.719
  cinA Streptococcus pneumoniae R6

72.554

99.054

0.719
  cinA Streptococcus pneumoniae D39

72.315

99.054

0.716
  cinA Streptococcus mutans UA159

69.834

99.527

0.695
  cinA Streptococcus suis isolate S10

54.567

98.345

0.537
  cinA Bacillus subtilis subsp. subtilis str. 168

44.418

99.527

0.442