Detailed information    

insolico Bioinformatically predicted

Overview

Name   cinA   Type   Machinery gene
Locus tag   ST90728_RS00370 Genome accession   NZ_CP065479
Coordinates   64260..65531 (+) Length   423 a.a.
NCBI ID   WP_022096618.1    Uniprot ID   -
Organism   Streptococcus thermophilus strain 90728     
Function   facilitate localization of RecA (predicted from homology)   
Homologous recombination

Genomic Context

Location: 59260..70531
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ST90728_RS00340 (ST90728_00335) - 59596..59987 (-) 392 Protein_46 LytTR family DNA-binding domain-containing protein -
  ST90728_RS00345 (ST90728_00340) - 60211..60516 (+) 306 WP_002949050.1 hypothetical protein -
  ST90728_RS00350 (ST90728_00345) mutL 60568..62511 (+) 1944 WP_179966861.1 DNA mismatch repair endonuclease MutL -
  ST90728_RS00355 (ST90728_00350) - 62640..62861 (+) 222 WP_011680602.1 hypothetical protein -
  ST90728_RS00360 (ST90728_00355) ruvA 63013..63603 (+) 591 WP_011680603.1 Holliday junction branch migration protein RuvA -
  ST90728_RS00365 (ST90728_00360) - 63610..64164 (+) 555 WP_347114193.1 DNA-3-methyladenine glycosylase I -
  ST90728_RS00370 (ST90728_00365) cinA 64260..65531 (+) 1272 WP_022096618.1 competence/damage-inducible protein A Machinery gene
  ST90728_RS00375 (ST90728_00370) recA 65567..66706 (+) 1140 WP_164177842.1 recombinase RecA Machinery gene
  ST90728_RS00380 (ST90728_00375) spx 66883..67281 (+) 399 WP_002949058.1 transcriptional regulator Spx -

Sequence

Protein


Download         Length: 423 a.a.        Molecular weight: 45956.32 Da        Isoelectric Point: 5.0948

>NTDB_id=510098 ST90728_RS00370 WP_022096618.1 64260..65531(+) (cinA) [Streptococcus thermophilus strain 90728]
MKAELITVGTEILTGQITNTNAQFLSEKLAELGIDVYFHTAVGDNENRLLSVLDQSSKRSDLVILCGGLGPTEDDLTKQT
LAKFLGKELIFDEEASKKLDSFFATRPKHTRTPNNERQAQIVEGAVPLQNLTGLAVGGIITVEGVTYVVLPGPPSELKPM
VNQELIPALTENHTTLYSRVLRFFGVGESQLVTIIKDLIVNQTDPTIAPYAKVGEVTLRLSTKASSQEEADRKLDVLEEQ
IRSTKTLDGKSLSDLIYGYGESNSLAYEVFYLLKKYGKTITAAESLTAGLFQASVADFPGASQVFKGGFVTYSMEEKAKM
LGIPLSKLEEHGVVSHFTAEKMAEGARVKTDSDYGIALTGVAGPDALEGHQAGTVFIGIADRNQVRSIKVVIGGRSRSDV
RYISTLYAFNLVRQALLQEDNSI

Nucleotide


Download         Length: 1272 bp        

>NTDB_id=510098 ST90728_RS00370 WP_022096618.1 64260..65531(+) (cinA) [Streptococcus thermophilus strain 90728]
ATGAAAGCTGAATTGATTACAGTAGGAACTGAAATTCTTACAGGGCAAATCACCAATACCAATGCCCAATTTTTATCTGA
AAAACTAGCTGAATTAGGAATTGACGTGTATTTTCACACAGCGGTAGGAGACAATGAAAACCGTCTACTTTCAGTCTTAG
ACCAGTCTAGTAAACGTAGCGATTTAGTCATACTCTGTGGAGGACTTGGCCCTACTGAGGATGACTTAACCAAACAAACA
TTGGCTAAGTTTTTAGGCAAAGAACTCATTTTTGATGAGGAGGCAAGTAAAAAACTGGATAGTTTCTTTGCTACTCGTCC
TAAACATACACGAACGCCTAATAATGAACGCCAAGCGCAAATTGTTGAGGGGGCTGTCCCCTTGCAAAATCTCACAGGTC
TGGCAGTTGGAGGAATTATTACTGTTGAAGGAGTGACCTATGTTGTCTTGCCTGGTCCGCCAAGTGAACTCAAACCTATG
GTGAACCAAGAGCTTATTCCAGCTCTTACAGAGAATCATACTACGCTTTATTCTAGAGTCCTAAGGTTTTTTGGTGTTGG
AGAAAGTCAATTGGTGACTATTATTAAAGATCTCATTGTTAACCAAACAGACCCAACCATTGCGCCCTATGCTAAAGTGG
GAGAAGTGACCCTTCGCTTATCAACAAAGGCATCGTCGCAAGAAGAAGCGGATCGAAAACTAGATGTTTTAGAAGAACAA
ATTCGTTCTACTAAAACTCTAGATGGAAAAAGCTTGTCTGATCTCATCTATGGATATGGAGAATCAAATAGCTTAGCTTA
TGAAGTGTTCTATTTGCTTAAGAAATATGGCAAAACTATTACTGCAGCTGAAAGTTTAACAGCTGGCTTATTTCAAGCTA
GTGTTGCTGATTTTCCTGGAGCTTCACAAGTATTCAAGGGTGGTTTTGTCACCTATAGCATGGAAGAAAAAGCTAAAATG
TTGGGTATTCCCTTATCTAAATTAGAAGAGCATGGTGTTGTTAGTCATTTTACAGCAGAAAAAATGGCTGAGGGTGCCCG
AGTTAAGACAGATAGTGATTACGGAATTGCGCTTACTGGAGTAGCAGGACCAGATGCTTTGGAAGGGCATCAAGCAGGTA
CAGTCTTTATTGGTATTGCCGATAGAAACCAAGTGCGGTCAATTAAGGTTGTTATAGGTGGAAGAAGTCGATCTGATGTT
AGATATATCAGTACACTCTATGCCTTTAACCTAGTTCGCCAAGCTTTATTACAAGAGGACAACTCAATTTAA

Domains

Predicted by InterproScan.

Competence-damaged protein (CinA)

(264-415)

Damage-inducible protein CinA KH domain (CinA_KH)

(178-243)

Probable molybdopterin binding domain (MoCF_biosynth)

(5-170)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cinA Streptococcus mitis SK321

74.463

99.054

0.738
  cinA Streptococcus mitis NCTC 12261

73.27

99.054

0.726
  cinA Streptococcus pneumoniae TIGR4

72.076

99.054

0.714
  cinA Streptococcus pneumoniae Rx1

71.838

99.054

0.712
  cinA Streptococcus pneumoniae R6

71.838

99.054

0.712
  cinA Streptococcus pneumoniae D39

71.599

99.054

0.709
  cinA Streptococcus mutans UA159

70.071

99.527

0.697
  cinA Streptococcus suis isolate S10

54.327

98.345

0.534
  cinA Bacillus subtilis subsp. subtilis str. 168

44.418

99.527

0.442