Detailed information    

insolico Bioinformatically predicted

Overview

Name   dprA   Type   Machinery gene
Locus tag   I3X05_RS16505 Genome accession   NZ_CP065217
Coordinates   3478906..3480009 (-) Length   367 a.a.
NCBI ID   WP_045569038.1    Uniprot ID   A0A0F2ITX6
Organism   Vibrio navarrensis strain 20-VB00237     
Function   ssDNA binding; loading RecA onto ssDNA (predicted from homology)   
DNA processing

Genomic Context

Location: 3473906..3485009
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  I3X05_RS16475 (I3X05_16825) hemF 3474444..3475361 (-) 918 WP_045569033.1 oxygen-dependent coproporphyrinogen oxidase -
  I3X05_RS16480 (I3X05_16830) - 3475391..3475948 (-) 558 WP_045569034.1 L-threonylcarbamoyladenylate synthase -
  I3X05_RS16485 (I3X05_16835) purE 3476133..3476618 (+) 486 WP_039460909.1 5-(carboxyamino)imidazole ribonucleotide mutase -
  I3X05_RS16490 (I3X05_16840) - 3476623..3477756 (+) 1134 WP_193157877.1 5-(carboxyamino)imidazole ribonucleotide synthase -
  I3X05_RS16495 (I3X05_16845) - 3477824..3478402 (-) 579 WP_337970864.1 topoisomerase DNA-binding C4 zinc finger domain-containing protein -
  I3X05_RS16500 (I3X05_16850) - 3478424..3478903 (-) 480 WP_045569037.1 DUF494 family protein -
  I3X05_RS16505 (I3X05_16855) dprA 3478906..3480009 (-) 1104 WP_045569038.1 DNA-processing protein DprA Machinery gene
  I3X05_RS16510 (I3X05_16860) - 3480009..3481106 (-) 1098 WP_045569039.1 LysM peptidoglycan-binding domain-containing protein -
  I3X05_RS16515 (I3X05_16865) def 3481245..3481757 (+) 513 WP_045569040.1 peptide deformylase -
  I3X05_RS16520 (I3X05_16870) fmt 3481791..3482738 (+) 948 WP_045569041.1 methionyl-tRNA formyltransferase -
  I3X05_RS16525 (I3X05_16875) rsmB 3482817..3484097 (+) 1281 WP_193157878.1 16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB -

Sequence

Protein


Download         Length: 367 a.a.        Molecular weight: 39663.19 Da        Isoelectric Point: 5.6335

>NTDB_id=508216 I3X05_RS16505 WP_045569038.1 3478906..3480009(-) (dprA) [Vibrio navarrensis strain 20-VB00237]
MSEQELIAWLSLSFTPQIGVKRLAKLLSIDSPLNILAYSDNALLNLGFSAVQLAYLRQEARRDVEASLTWQLQQGHHILT
LVDDDYPPLLKEAGAAPPYLFVKGEVGALSKPQLAMVGSRNASLEGLQHARQFAEFLVQQGLAVTSGLALGIDGHAHDGA
LNAGGDTIAVLGSGLEHIYPARHRKLAQRIAEQGALVSEFRPDAKPRAENFPRRNRIISGLALGVLVVEAAEKSGSLITA
RYAAEQGREVFALPCSISSVNGRGGNQLIKNGACLVSEPNDILREIQSLLDWSYQQQTGDLFSPLNTEEQLPFSELLANV
GSEATPVDILANRTNIPVQEVMMQLLELELSGHVVAINGGYIRRGRG

Nucleotide


Download         Length: 1104 bp        

>NTDB_id=508216 I3X05_RS16505 WP_045569038.1 3478906..3480009(-) (dprA) [Vibrio navarrensis strain 20-VB00237]
ATGTCAGAGCAAGAACTGATCGCTTGGTTAAGCTTAAGTTTTACGCCGCAGATCGGGGTAAAACGATTAGCCAAATTACT
CAGTATTGATTCTCCGCTCAATATTCTCGCCTACTCAGATAATGCATTGCTCAATTTGGGGTTTTCTGCCGTTCAACTCG
CCTATCTGCGGCAAGAGGCTCGCCGCGATGTGGAAGCGTCACTGACTTGGCAACTGCAACAAGGTCATCACATTCTCACC
TTAGTCGATGACGATTATCCGCCACTGCTTAAAGAAGCTGGAGCCGCGCCGCCTTATCTGTTTGTTAAAGGGGAGGTGGG
CGCACTGAGCAAGCCGCAACTTGCGATGGTTGGTAGTCGCAATGCCAGTCTAGAAGGGCTACAGCATGCTCGGCAGTTTG
CGGAGTTTTTAGTTCAACAGGGGCTTGCGGTGACCAGTGGTTTAGCGCTGGGTATTGATGGCCACGCTCACGATGGCGCA
CTCAATGCAGGTGGTGACACCATCGCCGTGCTAGGCTCAGGGCTCGAACACATTTATCCCGCTCGCCATCGCAAGTTGGC
GCAACGAATCGCCGAGCAAGGTGCGCTGGTGTCTGAGTTTCGCCCTGATGCTAAACCCCGTGCGGAGAACTTCCCTCGCC
GTAATCGTATTATCAGTGGCTTGGCGCTGGGGGTGTTGGTTGTGGAAGCGGCTGAAAAAAGCGGCTCACTCATCACCGCT
CGTTATGCGGCAGAGCAAGGGCGAGAAGTCTTTGCTCTGCCTTGTTCGATTTCTTCGGTGAATGGCCGAGGTGGCAATCA
ACTGATCAAAAACGGGGCGTGCTTAGTCTCTGAGCCCAATGACATCTTGCGTGAAATACAATCGTTACTGGATTGGTCTT
ATCAGCAGCAAACGGGAGATTTATTTTCTCCACTTAATACCGAAGAACAATTGCCATTTTCTGAGCTGTTAGCTAACGTA
GGAAGTGAGGCGACACCAGTTGATATTCTGGCAAACAGGACCAATATACCTGTGCAAGAAGTCATGATGCAGCTCCTAGA
GCTTGAGCTTTCAGGACATGTTGTTGCAATTAACGGTGGCTATATTCGAAGGGGGAGGGGCTAG

Domains

Predicted by InterproScan.

DNA recombination-mediator protein A (DNA_processg_A)

(74-277)

DprA winged helix domain (DprA_WH)

(315-360)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0F2ITX6

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  dprA Vibrio campbellii strain DS40M4

71.429

99.183

0.708
  dprA Vibrio cholerae strain A1552

56.873

100

0.575
  dprA Glaesserella parasuis strain SC1401

46.995

99.728

0.469
  dprA Haemophilus influenzae Rd KW20

44.142

100

0.441
  dprA Neisseria meningitidis strain C311

40.05

100

0.439
  dprA Neisseria meningitidis MC58

40.05

100

0.439
  dprA Neisseria gonorrhoeae MS11

39

100

0.425
  dprA Neisseria gonorrhoeae strain FA1090

38.75

100

0.422
  dprA Legionella pneumophila strain ERS1305867

47.525

82.561

0.392