Detailed information    

insolico Bioinformatically predicted

Overview

Name   cinA   Type   Machinery gene
Locus tag   I2438_RS10040 Genome accession   NZ_CP065190
Coordinates   2040463..2041734 (-) Length   423 a.a.
NCBI ID   WP_021321221.1    Uniprot ID   A0A922NUY3
Organism   Streptococcus equi subsp. zooepidemicus strain SEZ36     
Function   require for competence (predicted from homology)   
Unclear

Genomic Context

Location: 2035463..2046734
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  I2438_RS10010 (HCFMJIKG_01985) - 2035668..2035967 (-) 300 WP_021321220.1 DUF1292 domain-containing protein -
  I2438_RS10015 (HCFMJIKG_01986) ruvX 2035977..2036396 (-) 420 WP_015898660.1 Holliday junction resolvase RuvX -
  I2438_RS10020 (HCFMJIKG_01987) - 2036393..2036662 (-) 270 WP_012516439.1 IreB family regulatory phosphoprotein -
  I2438_RS10025 (HCFMJIKG_01988) spx 2036775..2037173 (-) 399 WP_012516440.1 transcriptional regulator Spx -
  I2438_RS10035 (HCFMJIKG_01991) recA 2039233..2040369 (-) 1137 WP_012516441.1 recombinase RecA Machinery gene
  I2438_RS10040 (HCFMJIKG_01992) cinA 2040463..2041734 (-) 1272 WP_021321221.1 competence/damage-inducible protein A Machinery gene
  I2438_RS10045 (HCFMJIKG_01993) - 2042420..2042710 (-) 291 WP_012516443.1 hypothetical protein -
  I2438_RS10050 (HCFMJIKG_01994) - 2042704..2043276 (-) 573 WP_021321222.1 phospholipase A2 SlaB -
  I2438_RS10055 (HCFMJIKG_01995) - 2043573..2044418 (+) 846 WP_012516446.1 helix-turn-helix domain-containing protein -
  I2438_RS10060 (HCFMJIKG_01996) - 2044855..2045406 (-) 552 WP_021321223.1 DNA-3-methyladenine glycosylase I -
  I2438_RS10065 (HCFMJIKG_01997) ruvA 2045416..2046012 (-) 597 WP_012678694.1 Holliday junction branch migration protein RuvA -

Sequence

Protein


Download         Length: 423 a.a.        Molecular weight: 45862.62 Da        Isoelectric Point: 6.5143

>NTDB_id=507796 I2438_RS10040 WP_021321221.1 2040463..2041734(-) (cinA) [Streptococcus equi subsp. zooepidemicus strain SEZ36]
MKAELIAVGTEILTGQIVNTNAQFLSEKMAELGIDVYFQTAVGDNEERLLSVIDIASQRSDLVILCGGLGPTDDDLTKQT
LAKYLRKALVFDEQAGQKLDAFFAHRKQAARTPNNQRQAQLIEGSVALQNQTGLAVGGLITVDRVTYVVLPGPPSELKPM
VKNELVPLLSASHASLYSRVLRFFGIGESQLVTALEDLIKHQTDPTIAPYAKTGEVTLRLSTKADNQALADERLNRLEAQ
LLSIRTVDNQPLRRLLYGYGEDNSLARETFELLKRSGKTITAAESLTAGLFQAQLTDFAGASQVFNGGFITYSIEEKARM
LGIPLVELQRHGVVSSFTAEQMAAQARCLTNSDIGIGLTGVAGPEALEGQPAGTVFIGLATKNKVESLKVVIGGRSRLDV
RYIAALYAFNMVRKALLKSENLL

Nucleotide


Download         Length: 1272 bp        

>NTDB_id=507796 I2438_RS10040 WP_021321221.1 2040463..2041734(-) (cinA) [Streptococcus equi subsp. zooepidemicus strain SEZ36]
ATGAAAGCTGAACTCATTGCGGTGGGAACCGAGATTCTGACTGGTCAGATTGTGAATACCAATGCTCAATTTTTATCAGA
AAAAATGGCGGAGCTTGGTATTGATGTTTATTTTCAAACAGCTGTAGGAGATAATGAAGAGCGTTTGCTTTCTGTTATTG
ATATTGCTAGCCAGCGAAGTGATTTAGTGATTTTATGTGGTGGTCTTGGTCCAACAGATGATGATCTAACGAAGCAGACC
TTAGCTAAGTATCTAAGAAAAGCTTTGGTCTTTGATGAGCAGGCAGGTCAAAAATTAGATGCTTTTTTTGCACATCGTAA
GCAAGCTGCTAGGACACCAAATAATCAACGTCAGGCGCAGCTGATTGAAGGCTCTGTTGCTTTGCAAAATCAAACAGGAC
TTGCAGTAGGTGGGTTAATAACTGTAGATAGGGTAACCTATGTTGTCTTACCAGGGCCTCCAAGTGAGCTAAAGCCTATG
GTAAAAAATGAGCTGGTGCCCCTTCTTTCAGCTAGTCACGCCAGTCTATACTCAAGAGTGCTGCGTTTTTTTGGCATTGG
TGAAAGTCAACTGGTGACTGCTCTGGAGGATTTGATTAAGCATCAAACAGATCCCACCATTGCTCCTTATGCAAAGACCG
GCGAGGTAACACTGCGACTATCCACAAAGGCTGACAACCAAGCATTAGCTGATGAAAGGCTGAATCGACTAGAGGCGCAG
CTCTTATCCATAAGAACTGTAGATAATCAACCCTTACGGCGTTTGCTTTATGGCTATGGGGAGGATAATTCCTTGGCGCG
TGAGACCTTTGAGCTATTGAAGCGAAGTGGTAAGACGATAACAGCAGCTGAAAGCTTAACAGCAGGACTGTTTCAGGCTC
AGCTAACTGATTTTGCGGGAGCTTCACAGGTGTTTAACGGTGGCTTTATCACCTACAGCATTGAAGAAAAAGCAAGAATG
CTTGGCATTCCATTGGTTGAGCTACAAAGGCATGGTGTTGTGAGCTCTTTCACAGCTGAGCAAATGGCTGCGCAGGCACG
CTGCTTGACCAATTCGGATATCGGTATTGGTCTAACAGGTGTTGCTGGCCCAGAGGCACTTGAGGGACAGCCAGCAGGAA
CAGTTTTCATTGGCCTTGCCACTAAGAATAAGGTAGAATCTCTTAAAGTTGTTATAGGAGGCCGTAGCCGTTTGGACGTG
CGGTATATTGCTGCCCTATATGCTTTTAATATGGTTCGTAAAGCTTTATTAAAATCAGAGAATTTGCTATAA

Domains

Predicted by InterproScan.

Competence-damaged protein (CinA)

(263-416)

Damage-inducible protein CinA KH domain (CinA_KH)

(178-241)

Probable molybdopterin binding domain (MoCF_biosynth)

(5-169)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cinA Streptococcus mutans UA159

70.449

100

0.704
  cinA Streptococcus mitis NCTC 12261

70.264

98.582

0.693
  cinA Streptococcus mitis SK321

70.264

98.582

0.693
  cinA Streptococcus pneumoniae TIGR4

69.784

98.582

0.688
  cinA Streptococcus pneumoniae Rx1

69.784

98.582

0.688
  cinA Streptococcus pneumoniae R6

69.784

98.582

0.688
  cinA Streptococcus pneumoniae D39

69.544

98.582

0.686
  cinA Streptococcus suis isolate S10

53.461

99.054

0.53
  cinA Bacillus subtilis subsp. subtilis str. 168

47.608

98.818

0.47