Detailed information NTG0050724

Bioinformatically predicted

Overview

• Name: comR
• Type: Regulator
• Locus tag: SMULJ23_RS00355
• Genome accession: NC_017768
• Coordinates: 58189..59103 (+)
• Length: 304 a.a.
• NCBI ID: WP_002300254.1
• Uniprot ID: -
• Organism: Streptococcus mutans LJ23
• Function: activate transcription of comX (predicted from homology) Competence regulation

Genomic Context

Location: 53189..64103

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SMULJ23_RS00330 (SMULJ23_0044)	-	53636..53917 (+)	282	WP_002266649.1	hypothetical protein	-
SMULJ23_RS00335 (SMULJ23_0045)	-	53911..54336 (+)	426	WP_002266650.1	SRPBCC family protein	-
SMULJ23_RS00340 (SMULJ23_0046)	-	54367..55407 (+)	1041	WP_002270802.1	hypothetical protein	-
SMULJ23_RS10580	-	55400..55540 (+)	141	WP_002266374.1	hypothetical protein	-
SMULJ23_RS00345 (SMULJ23_0047)	purB	55800..57098 (+)	1299	WP_002263398.1	adenylosuccinate lyase	-
SMULJ23_RS00350 (SMULJ23_0048)	-	57118..57807 (+)	690	WP_014677674.1	DNA alkylation repair protein	-
SMULJ23_RS00355 (SMULJ23_0049)	comR	58189..59103 (+)	915	WP_002300254.1	helix-turn-helix domain-containing protein	Regulator
SMULJ23_RS00360 (SMULJ23_0050)	-	59635..61476 (-)	1842	WP_002266377.1	carbohydrate-binding domain-containing protein	-
SMULJ23_RS00365 (SMULJ23_0051)	ruvB	61811..62806 (+)	996	WP_002263402.1	Holliday junction branch migration DNA helicase RuvB	-
SMULJ23_RS00370 (SMULJ23_0052)	-	62844..63269 (+)	426	WP_002264681.1	low molecular weight protein-tyrosine-phosphatase	-
SMULJ23_RS00375 (SMULJ23_0053)	-	63334..63717 (+)	384	WP_011074470.1	membrane protein	-

Sequence

Protein

• Length: 304 a.a.
• Molecular weight: 35299.50 Da
• Isoelectric Point: 5.0064

>NTDB_id=50724 SMULJ23_RS00355 WP_002300254.1 58189..59103(+) (comR) [Streptococcus mutans LJ23]
MLKDFGKKIKNLRLEKGLTKEAVCLDESQLSTRQLTRIESGQSMPTLNKAIYIAGRLGVTLGYLTDGENVELPSRYKELK
YLLLRTPTYGDQQRLAEKETYFDEIFSQFYDDLPEEEQLIIDGLQSKLDIHFSDNIDFGVGILNDYFDQILRKTNYQVND
LILIDLYFSCLTVSGLDSAIFDSRKYNQLLETLLKQVDCLPLEDLFVLNNVLLNNFGLLLELKKYDFVKQLIAVSNKIMA
RTYDFQKKPIVNLLTWKHHLFVEKDYAKAKKSYDAAILFAQLTENINLRENLEKEWQKDSQNGT

Nucleotide

• Length: 915 bp

>NTDB_id=50724 SMULJ23_RS00355 WP_002300254.1 58189..59103(+) (comR) [Streptococcus mutans LJ23]
ATGTTAAAAGATTTTGGGAAGAAAATTAAGAACCTGAGGTTAGAAAAGGGGCTGACCAAAGAGGCTGTCTGCCTTGATGA
ATCGCAGTTGTCAACACGGCAGCTGACTAGAATTGAATCAGGACAGTCTATGCCAACTCTTAATAAAGCTATTTATATTG
CAGGACGTTTAGGAGTAACGCTTGGCTATTTAACGGACGGAGAAAATGTCGAGTTACCCAGTCGTTATAAAGAACTAAAA
TATTTATTATTACGAACGCCAACCTATGGTGACCAACAAAGATTAGCTGAAAAAGAAACCTATTTTGACGAGATTTTTAG
TCAGTTTTATGATGATTTGCCTGAAGAAGAACAATTGATTATTGATGGTTTACAATCGAAACTAGATATTCATTTTAGTG
ACAATATCGATTTTGGCGTTGGTATTTTAAATGACTATTTTGATCAGATTTTAAGAAAAACCAATTATCAGGTCAATGAT
TTGATTCTGATTGATCTCTATTTTTCCTGCTTAACTGTTAGTGGTTTGGATTCAGCTATTTTTGATTCAAGAAAATATAA
TCAATTATTGGAGACATTGCTTAAGCAGGTAGACTGCCTTCCATTGGAAGATCTTTTCGTTTTAAATAATGTTTTATTGA
ATAATTTTGGACTCCTCTTAGAATTGAAAAAATATGATTTTGTTAAGCAGCTTATTGCTGTCAGCAATAAAATCATGGCT
AGAACTTATGATTTTCAAAAAAAGCCTATTGTTAATCTTCTGACATGGAAGCATCATTTATTTGTTGAAAAAGATTATGC
GAAAGCTAAAAAGAGCTATGATGCTGCTATCTTATTTGCCCAGTTAACAGAAAACATTAATTTAAGAGAAAATTTGGAGA
AAGAATGGCAAAAAGATTCTCAGAACGGGACATAA

Domains

Predicted by InterproScan.

• Helix-turn-helix (HTH_3) (9-64)

• ComR tetratricopeptide (ComR_TPR) (73-296)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comR	Streptococcus mutans UA159	98.026	100	0.98
comR	Streptococcus infantarius subsp. infantarius ATCC BAA-102	52.431	94.737	0.497
comR	Streptococcus pyogenes MGAS8232	47.351	99.342	0.47
comR	Streptococcus pyogenes MGAS315	47.492	98.355	0.467
comR	Streptococcus suis P1/7	43.478	98.355	0.428
comR	Streptococcus suis 05ZYH33	43.478	98.355	0.428
comR	Streptococcus suis D9	37	98.684	0.365