Detailed information    

insolico Bioinformatically predicted

Overview

Name   comD/blpH   Type   Regulator
Locus tag   SANR_RS12230 Genome accession   NC_022239
Coordinates   557680..558987 (-) Length   435 a.a.
NCBI ID   WP_003037258.1    Uniprot ID   -
Organism   Streptococcus anginosus C238     
Function   phosphorylation of ComE; regulation of comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 552680..563987
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SANR_RS02830 (SANR_0553) - 553012..553386 (-) 375 WP_003037526.1 hypothetical protein -
  SANR_RS02835 (SANR_0554) comA/nlmT 553867..556017 (+) 2151 WP_020999513.1 peptide cleavage/export ABC transporter Regulator
  SANR_RS02840 (SANR_0555) - 556028..557389 (+) 1362 WP_003037280.1 bacteriocin secretion accessory protein -
  SANR_RS02845 (SANR_0556) - 557486..557635 (+) 150 WP_003037249.1 ComC/BlpC family leader-containing pheromone/bacteriocin -
  SANR_RS12230 (SANR_0557) comD/blpH 557680..558987 (-) 1308 WP_003037258.1 sensor histidine kinase Regulator
  SANR_RS02855 (SANR_0558) comE/blpR 558992..559738 (-) 747 WP_025271905.1 response regulator transcription factor Regulator
  SANR_RS02860 (SANR_0559) - 559907..560620 (-) 714 WP_003037434.1 CPBP family intramembrane glutamic endopeptidase -
  SANR_RS11820 - 560852..560920 (+) 69 Protein_533 bacteriocin class II family protein -
  SANR_RS12095 - 560950..561075 (+) 126 WP_003037205.1 hypothetical protein -
  SANR_RS02870 (SANR_0560) - 561163..561483 (+) 321 WP_003037422.1 hypothetical protein -
  SANR_RS02875 (SANR_0561) - 561491..561712 (+) 222 WP_003025422.1 Blp family class II bacteriocin -
  SANR_RS11100 (SANR_0562) - 562027..562278 (+) 252 WP_020998893.1 hypothetical protein -
  SANR_RS02880 (SANR_0563) - 562676..562996 (+) 321 WP_003037365.1 hypothetical protein -
  SANR_RS02885 (SANR_0564) - 563004..563237 (+) 234 WP_003025420.1 garvicin Q family class II bacteriocin -
  SANR_RS02890 (SANR_0565) - 563289..563579 (+) 291 WP_003025419.1 bacteriocin immunity protein -

Sequence

Protein


Download         Length: 435 a.a.        Molecular weight: 50300.86 Da        Isoelectric Point: 8.6778

>NTDB_id=50794 SANR_RS12230 WP_003037258.1 557680..558987(-) (comD/blpH) [Streptococcus anginosus C238]
MVQLSLIIIDMFLLLFLFSYISRQKLTTRTYLIAILTNLLYSIIFSFIPNSLFSYLIGPTYFLIFSWIVGKSYNKTLKIF
YGLFPITLWNLIQRLIIFFISPLFSFSVESLNKSFFGPIVTSIMATLIVLLFLRLIQYNFKTLKSQKINHNDKKIIIFVN
ISMIIYHLIVQVLSYLENENNLQTLNFRESLVVLYLILFVSVANYLDRHLRERIQNDLMLQKDLQLKNMENYSHHIEELY
TEVRSFRHDYANILTTLKLGIEQNDIGIVKNVYHSVLKDSNKRFRNPKYDIGRLVHIKNDALKSLLAAKFAQAQEHNVSV
SLEVPEDICPQGMELVDFITIVSILCDNAIEATTPTMTIAYVLSENKQVFSIENAIKEEHIDMSYIFDAGVSSKGSGRGI
GLSNVLAILDRYPNVSLTSASQNYRFQHVLEIHLN

Nucleotide


Download         Length: 1308 bp        

>NTDB_id=50794 SANR_RS12230 WP_003037258.1 557680..558987(-) (comD/blpH) [Streptococcus anginosus C238]
ATGGTGCAATTATCATTGATTATCATAGACATGTTTTTATTGTTGTTTCTTTTTTCCTACATTAGTAGACAAAAATTAAC
AACTAGAACATATCTGATAGCAATTCTAACCAATTTACTTTATAGTATAATTTTTTCTTTTATTCCAAATAGTTTATTTT
CTTATCTGATAGGTCCAACTTATTTTTTAATTTTTTCTTGGATTGTTGGAAAATCTTACAACAAAACGTTAAAAATTTTT
TACGGACTTTTTCCAATCACACTATGGAATTTAATTCAACGCTTGATTATTTTTTTCATATCTCCTTTATTTAGTTTTAG
TGTAGAAAGCCTCAATAAAAGTTTTTTTGGTCCGATTGTCACCTCAATTATGGCGACGCTGATAGTATTACTTTTTTTGC
GTTTAATTCAATATAATTTTAAGACATTAAAATCTCAAAAAATTAATCACAACGATAAGAAAATTATCATTTTTGTAAAT
ATCAGCATGATTATTTATCATCTTATTGTTCAAGTTCTATCTTATTTAGAAAATGAGAATAACTTACAGACACTAAATTT
TAGAGAAAGTTTAGTAGTTCTTTATCTTATCCTTTTTGTGAGTGTTGCCAATTATTTAGACCGTCATTTACGAGAGAGAA
TCCAAAATGATTTAATGCTTCAAAAAGATTTACAGTTAAAAAATATGGAAAACTACAGTCATCACATTGAGGAATTGTAC
ACAGAAGTTCGGAGCTTTCGGCATGATTACGCTAATATTTTAACAACCTTGAAATTAGGAATTGAGCAAAATGATATAGG
CATTGTAAAAAATGTCTATCATTCTGTTTTGAAAGATTCCAATAAGCGTTTTCGCAATCCCAAGTATGATATTGGACGGT
TAGTCCATATCAAAAACGATGCCTTAAAAAGCCTGCTAGCTGCTAAATTTGCACAAGCTCAAGAGCATAATGTATCCGTT
TCATTGGAGGTTCCAGAAGATATTTGTCCACAAGGAATGGAATTAGTTGACTTTATCACCATTGTCTCCATTTTGTGTGA
TAATGCGATTGAAGCTACCACTCCAACTATGACGATTGCTTATGTTTTGTCAGAAAACAAGCAGGTATTCTCCATTGAAA
ATGCTATAAAAGAAGAGCATATAGACATGTCTTATATTTTTGATGCGGGAGTTAGTTCTAAAGGATCTGGGCGAGGAATT
GGATTATCAAATGTCTTAGCAATTCTGGATCGATATCCAAATGTTTCTCTTACTAGCGCTAGTCAAAATTATCGTTTCCA
GCATGTCCTTGAGATTCATCTGAATTAA

Domains

Predicted by InterProScan.

GHKL domain (HATPase_c_5)

(333-428)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comD/blpH Streptococcus mutans UA159

38.005

96.782

0.368

Multiple sequence alignment