Detailed information    

insolico Bioinformatically predicted

Overview

Name   comA/nlmT   Type   Regulator
Locus tag   SANR_RS02835 Genome accession   NC_022239
Coordinates   553867..556017 (+) Length   716 a.a.
NCBI ID   WP_020999513.1    Uniprot ID   -
Organism   Streptococcus anginosus C238     
Function   transport of ComC (predicted from homology)   
Competence regulation

Genomic Context

Location: 548867..561017
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SANR_RS02810 (SANR_0549) holA 549784..550821 (+) 1038 WP_003034316.1 DNA polymerase III subunit delta -
  SANR_RS02815 (SANR_0550) - 550892..551497 (+) 606 WP_003034324.1 superoxide dismutase -
  SANR_RS11090 - 551590..552941 (+) 1352 WP_148290568.1 IS3 family transposase -
  SANR_RS02830 (SANR_0553) - 553012..553386 (-) 375 WP_003037526.1 hypothetical protein -
  SANR_RS02835 (SANR_0554) comA/nlmT 553867..556017 (+) 2151 WP_020999513.1 peptide cleavage/export ABC transporter Regulator
  SANR_RS02840 (SANR_0555) - 556028..557389 (+) 1362 WP_003037280.1 bacteriocin secretion accessory protein -
  SANR_RS02845 (SANR_0556) - 557486..557635 (+) 150 WP_003037249.1 ComC/BlpC family leader-containing pheromone/bacteriocin -
  SANR_RS12230 (SANR_0557) comD/blpH 557680..558987 (-) 1308 WP_003037258.1 sensor histidine kinase Regulator
  SANR_RS02855 (SANR_0558) comE/blpR 558992..559738 (-) 747 WP_025271905.1 response regulator transcription factor Regulator
  SANR_RS02860 (SANR_0559) - 559907..560620 (-) 714 WP_003037434.1 CPBP family intramembrane glutamic endopeptidase -
  SANR_RS11820 - 560852..560920 (+) 69 Protein_533 bacteriocin class II family protein -

Sequence

Protein


Download         Length: 716 a.a.        Molecular weight: 80267.79 Da        Isoelectric Point: 9.4610

>NTDB_id=50723 SANR_RS02835 WP_020999513.1 553867..556017(+) (comA/nlmT) [Streptococcus anginosus C238]
MNVKKTFVPQIDARDCGVAALASIAKYYGSDYSLAHLRELAKTSKEGTTALGIVQAAQEIGFETRPIQGDMSLFDMEAIP
YPFIVHVQKKGKLPHYYVIYKNTKKGLLVGDPDPSVKITKISKEQFTKEWTGVAIFLAPKPSYKPHKDKKNGLASFLPLI
FKQRSLIFYIVLASLLVTLINIVGSYYLQSVLDEYIPNQMKSTLGIVSIGLIITYILQQMMSFSRDYLLIVLSQRLTIDV
ILSYIRHIFELPMSFFATRRTGEIISRFTDANSIIDALASTILSLLLDLSILIIVGSVLLLQNANLFLLTLLAIPIYALI
IFAFMKPFEKMNNDVMQSNAMVNSAIIEDINGIETIKSLTSEESRYQKIDSEFVDYLDKTFKLSKYSIVQTALKQGAQFV
LNVVILWVGASLVMSQKISIGQLITFNALLSYFTSPLESIINLQTKLQSAKVANHRLNEIYLVESEFKTKQVLTEKNFLA
GDITFHNVSYKYGFGRDTLSDISLTIKKGDKISLFGISGSGKTTLAKMIVHFYEPYQGQIRLNGNDLKTIDKKVLRQYIN
YLPQQAYIFSGSILDNLTLGADQTVSQSDILRACEIAEIRSDIEQMPMGYQIELSDGAGLSGGQKQRIALARALLTKSPI
LILDEATSGLDVLTEKKVIDNLMKLPDKTIIFVAHRLSISKRTNQIIVLDQGKVIETGSHTELIERKGFYYHLFNK

Nucleotide


Download         Length: 2151 bp        

>NTDB_id=50723 SANR_RS02835 WP_020999513.1 553867..556017(+) (comA/nlmT) [Streptococcus anginosus C238]
GTGAATGTTAAGAAAACATTTGTTCCTCAAATAGATGCAAGAGATTGCGGTGTCGCTGCGCTTGCTTCCATTGCAAAATA
CTATGGTTCAGACTACTCTCTTGCACATCTGAGAGAACTTGCTAAGACAAGTAAAGAAGGGACAACGGCTCTTGGAATTG
TTCAAGCAGCGCAAGAAATAGGTTTTGAGACACGACCGATTCAAGGGGATATGTCTTTGTTTGATATGGAAGCTATTCCC
TATCCTTTTATCGTTCATGTTCAGAAAAAAGGTAAACTCCCACATTATTATGTTATCTATAAAAATACGAAAAAAGGTCT
GCTAGTTGGAGATCCTGATCCAAGTGTAAAAATAACTAAGATTAGCAAAGAACAATTTACTAAAGAATGGACAGGTGTTG
CTATCTTTCTCGCACCAAAACCTAGCTATAAACCTCATAAGGATAAGAAAAATGGACTTGCTAGCTTTTTACCACTCATC
TTTAAACAGCGTTCTTTGATTTTTTATATTGTCTTAGCTAGTTTGCTCGTGACCCTCATCAACATTGTTGGCTCCTATTA
TCTGCAAAGCGTTTTGGACGAATACATCCCAAATCAGATGAAATCAACTCTTGGAATCGTTTCAATTGGGCTTATCATTA
CTTACATCTTGCAGCAAATGATGAGTTTTTCCAGAGATTACTTATTGATTGTACTTAGTCAGCGGCTGACCATTGATGTG
ATTTTATCATATATTCGACACATTTTTGAATTACCGATGTCTTTTTTTGCTACGAGACGCACTGGAGAGATTATTTCTCG
TTTTACAGATGCCAACTCTATTATTGATGCTCTAGCGTCAACAATTCTATCCCTCCTTCTTGATTTGTCCATTTTGATAA
TTGTCGGCAGTGTTCTTTTACTGCAAAATGCCAATCTCTTTCTACTCACTTTGCTTGCAATTCCTATCTACGCTCTCATT
ATTTTTGCTTTTATGAAGCCTTTTGAAAAAATGAACAACGATGTTATGCAAAGCAATGCTATGGTGAATTCTGCTATTAT
CGAAGATATCAATGGAATTGAAACCATTAAATCTTTAACTAGCGAAGAAAGTCGTTACCAAAAGATTGATAGCGAGTTTG
TTGATTATCTGGATAAAACTTTCAAATTAAGTAAATATTCCATTGTGCAGACCGCTCTCAAACAAGGAGCACAATTTGTT
TTGAATGTGGTTATTCTCTGGGTTGGAGCGTCCTTAGTCATGTCTCAAAAGATTTCAATTGGTCAACTGATTACTTTCAA
TGCTCTCCTTTCATACTTTACTAGTCCGCTTGAAAGTATCATCAATCTTCAAACCAAACTGCAATCAGCTAAAGTTGCCA
ATCATCGACTGAATGAAATTTATCTGGTAGAATCTGAATTCAAAACCAAACAAGTCCTTACGGAGAAAAATTTCTTAGCT
GGTGATATTACTTTTCATAACGTCTCCTATAAATATGGCTTTGGACGAGATACTTTATCAGATATTAGTTTAACTATCAA
GAAGGGAGATAAAATCAGTCTTTTCGGTATTAGCGGTTCGGGAAAAACAACACTTGCTAAGATGATTGTTCATTTTTATG
AGCCTTATCAAGGACAAATTCGCCTCAATGGAAATGACCTCAAGACAATTGATAAGAAAGTTCTTCGGCAATATATCAAC
TACTTACCTCAGCAAGCTTACATATTTAGTGGTTCCATTCTAGACAACCTCACATTAGGAGCCGATCAAACAGTTTCTCA
ATCAGATATTCTTCGTGCCTGTGAAATTGCAGAAATTCGTTCAGATATCGAACAAATGCCCATGGGATACCAGATAGAAT
TGTCTGACGGAGCTGGATTATCTGGTGGGCAAAAACAGCGAATCGCACTTGCACGCGCTCTCCTGACGAAATCTCCCATT
CTCATTTTAGATGAAGCAACGAGTGGATTAGATGTTCTAACAGAGAAAAAAGTCATTGATAATCTCATGAAATTACCCGA
CAAAACCATTATTTTTGTTGCTCATCGTCTCAGCATTTCAAAGCGTACAAATCAGATTATCGTCCTTGACCAAGGAAAAG
TGATTGAAACGGGTTCTCATACTGAATTGATAGAAAGAAAAGGTTTTTATTATCATCTATTTAATAAATAA

Domains

Predicted by InterProScan.

ABC transporter transmembrane region (ABC_membrane)

(167-437)

ABC transporter (ABC_tran)

(499-648)

Peptidase C39 family (Peptidase_C39)

(6-141)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comA/nlmT Streptococcus mutans UA159

71.65

99.022

0.709
  comA Streptococcus mitis NCTC 12261

66.199

99.581

0.659
  comA Streptococcus mitis SK321

65.778

99.581

0.655
  comA Streptococcus gordonii str. Challis substr. CH1

65.638

99.581

0.654
  comA Streptococcus pneumoniae D39

65.358

99.581

0.651
  comA Streptococcus pneumoniae Rx1

65.358

99.581

0.651
  comA Streptococcus pneumoniae R6

65.358

99.581

0.651
  comA Streptococcus pneumoniae TIGR4

64.937

99.581

0.647

Multiple sequence alignment