Detailed information NTG0506574

Bioinformatically predicted

Overview

• Name: cinA
• Type: Machinery gene
• Locus tag: I2436_RS09230
• Genome accession: NZ_CP065060
• Coordinates: 1957582..1958853 (-)
• Length: 423 a.a.
• NCBI ID: WP_206152833.1
• Uniprot ID: -
• Organism: Streptococcus equi subsp. zooepidemicus strain SEZ28
• Function: require for competence (predicted from homology) Unclear

Genomic Context

Location: 1952582..1963853

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
I2436_RS09205 (GDAKBCAL_01840)	-	1954471..1954770 (-)	300	WP_021321220.1	DUF1292 domain-containing protein	-
I2436_RS09210 (GDAKBCAL_01841)	ruvX	1954780..1955199 (-)	420	WP_012678687.1	Holliday junction resolvase RuvX	-
I2436_RS09215 (GDAKBCAL_01842)	-	1955196..1955465 (-)	270	WP_012516439.1	IreB family regulatory phosphoprotein	-
I2436_RS09220 (GDAKBCAL_01843)	spx	1955578..1955976 (-)	399	WP_012516440.1	transcriptional regulator Spx	-
I2436_RS09225 (GDAKBCAL_01844)	recA	1956352..1957488 (-)	1137	WP_012678688.1	recombinase RecA	Machinery gene
I2436_RS09230 (GDAKBCAL_01845)	cinA	1957582..1958853 (-)	1272	WP_206152833.1	competence/damage-inducible protein A	Machinery gene
I2436_RS09235 (GDAKBCAL_01846)	-	1959539..1959829 (-)	291	WP_012516443.1	hypothetical protein	-
I2436_RS09240 (GDAKBCAL_01847)	-	1959823..1960395 (-)	573	WP_012516444.1	phosphlipase A2 SlaA	-
I2436_RS09245 (GDAKBCAL_01848)	-	1960692..1961537 (+)	846	WP_206152834.1	helix-turn-helix transcriptional regulator	-
I2436_RS09250 (GDAKBCAL_01849)	-	1961970..1962521 (-)	552	WP_206152835.1	DNA-3-methyladenine glycosylase I	-
I2436_RS09255 (GDAKBCAL_01850)	ruvA	1962531..1963127 (-)	597	WP_206152836.1	Holliday junction branch migration protein RuvA	-

Sequence

Protein

• Length: 423 a.a.
• Molecular weight: 45980.65 Da
• Isoelectric Point: 5.3232

>NTDB_id=506574 I2436_RS09230 WP_206152833.1 1957582..1958853(-) (cinA) [Streptococcus equi subsp. zooepidemicus strain SEZ28]
MKAELIAVGTEILTGQIVNTNAQFLSEKMAELGIDVYFQTAVGDNEERLLSVIDIASQRSDLVILCGGLGPTDDDLTKQT
LAKYLGKALVFDEQAGQKLDAFFAHRKHTARTPNNQRQAQLIEGSVALQNQTGLAVGGLITVDGVTYVVLPGPPSELKPM
VKNELVPLLSASHASLYSRVLRFFGIGESQLVTALEDLIKYQTDPTIAPYAKTGEVTLRLSTKADHQALANERLDQLELQ
LLSIRTIDNHPLRRLLYGYGEDNSLARETFELLKRSGKTITAAESLTAGLFQAQLTDFAGASQVFNGGFITYSIEEKARM
LGIPLVELQRHGVVSSFTAEQMAAQARCLTDSDIGIGLTGVAGPEELEEQPAGTVFIGLATKNKVESLKVVIGGRSRLDV
RYIATLYAFNMVRKTLLKSENLL

Nucleotide

• Length: 1272 bp

>NTDB_id=506574 I2436_RS09230 WP_206152833.1 1957582..1958853(-) (cinA) [Streptococcus equi subsp. zooepidemicus strain SEZ28]
ATGAAAGCTGAACTCATTGCGGTGGGAACCGAGATTCTGACTGGTCAGATTGTGAATACCAATGCTCAATTTTTATCAGA
AAAAATGGCGGAGCTTGGTATTGATGTTTATTTTCAAACAGCTGTAGGAGATAATGAAGAGCGTTTGCTTTCTGTTATTG
ATATTGCTAGCCAGCGAAGTGATTTAGTGATTTTATGTGGTGGTCTTGGTCCAACAGATGATGATCTAACGAAGCAGACC
TTAGCTAAGTATCTGGGAAAAGCTTTGGTCTTTGATGAGCAGGCAGGTCAAAAATTAGATGCTTTTTTTGCACATCGTAA
GCATACTGCTAGGACACCAAACAACCAACGTCAGGCGCAGCTGATTGAAGGCTCTGTTGCTTTGCAAAATCAAACAGGAC
TTGCAGTAGGTGGCTTGATCACTGTAGATGGGGTAACCTATGTTGTCTTACCAGGGCCTCCAAGTGAGTTAAAGCCTATG
GTAAAAAATGAGCTGGTACCCCTTCTTTCAGCTAGTCACGCTAGTCTGTACTCAAGAGTGCTGCGCTTTTTTGGCATTGG
TGAGAGTCAACTGGTGACTGCTCTGGAGGATTTGATTAAGTATCAAACAGATCCTACTATTGCTCCTTATGCAAAGACCG
GCGAGGTAACACTGCGACTATCCACAAAGGCTGATCATCAAGCATTAGCTAATGAAAGGCTGGATCAGCTGGAGTTACAG
CTCTTATCCATAAGAACCATAGATAATCACCCCTTACGGCGTTTGCTTTATGGCTATGGGGAGGATAATTCCTTGGCACG
TGAGACCTTTGAGCTATTGAAGCGAAGTGGCAAGACGATAACAGCAGCTGAAAGCTTGACAGCAGGACTGTTTCAAGCCC
AGCTAACTGATTTTGCGGGAGCTTCACAGGTGTTTAACGGTGGCTTTATCACCTACAGCATTGAAGAAAAAGCAAGAATG
CTTGGTATTCCATTGGTTGAGCTCCAAAGGCATGGTGTTGTGAGCTCTTTTACAGCTGAGCAAATGGCTGCGCAGGCACG
TTGCTTGACCGATTCAGATATCGGTATTGGTCTAACAGGTGTTGCTGGTCCAGAGGAACTCGAGGAGCAGCCAGCAGGAA
CAGTTTTCATTGGCCTTGCCACTAAGAATAAGGTAGAATCTCTTAAAGTTGTCATAGGAGGTCGCAGCCGTTTGGACGTG
CGGTACATTGCTACTCTGTACGCTTTTAATATGGTTCGTAAAACTTTATTAAAATCAGAGAATTTGCTATAA

Domains

Predicted by InterproScan.

• Damage-inducible protein CinA KH domain (CinA_KH) (178-240)

• Probable molybdopterin binding domain (MoCF_biosynth) (5-169)

• Competence-damaged protein (CinA) (263-416)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
cinA	Streptococcus mutans UA159	70.922	100	0.709
cinA	Streptococcus mitis NCTC 12261	70.743	98.582	0.697
cinA	Streptococcus mitis SK321	70.743	98.582	0.697
cinA	Streptococcus pneumoniae TIGR4	70.264	98.582	0.693
cinA	Streptococcus pneumoniae Rx1	70.264	98.582	0.693
cinA	Streptococcus pneumoniae R6	70.264	98.582	0.693
cinA	Streptococcus pneumoniae D39	70.024	98.582	0.69
cinA	Streptococcus suis isolate S10	54.177	99.054	0.537
cinA	Bacillus subtilis subsp. subtilis str. 168	47.129	98.818	0.466