Detailed information    

insolico Bioinformatically predicted

Overview

Name   cinA   Type   Machinery gene
Locus tag   I2435_RS09675 Genome accession   NZ_CP065059
Coordinates   2014153..2015424 (-) Length   423 a.a.
NCBI ID   WP_043983216.1    Uniprot ID   -
Organism   Streptococcus equi subsp. zooepidemicus strain SEZ25     
Function   require for competence (predicted from homology)   
Unclear

Genomic Context

Location: 2009153..2020424
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  I2435_RS09650 (JFMEOBDD_01946) - 2011043..2011342 (-) 300 WP_012516437.1 DUF1292 domain-containing protein -
  I2435_RS09655 (JFMEOBDD_01947) ruvX 2011352..2011771 (-) 420 WP_012678687.1 Holliday junction resolvase RuvX -
  I2435_RS09660 (JFMEOBDD_01948) - 2011768..2012037 (-) 270 WP_012516439.1 IreB family regulatory phosphoprotein -
  I2435_RS09665 (JFMEOBDD_01949) spx 2012149..2012547 (-) 399 WP_012516440.1 transcriptional regulator Spx -
  I2435_RS09670 (JFMEOBDD_01950) recA 2012923..2014059 (-) 1137 WP_012678688.1 recombinase RecA Machinery gene
  I2435_RS09675 (JFMEOBDD_01951) cinA 2014153..2015424 (-) 1272 WP_043983216.1 competence/damage-inducible protein A Machinery gene
  I2435_RS09680 (JFMEOBDD_01952) - 2016110..2016400 (-) 291 WP_012516443.1 hypothetical protein -
  I2435_RS09685 (JFMEOBDD_01953) - 2016394..2016966 (-) 573 WP_021321222.1 phospholipase A2 SlaB -
  I2435_RS09690 (JFMEOBDD_01954) - 2017263..2018108 (+) 846 WP_012678692.1 helix-turn-helix transcriptional regulator -
  I2435_RS09695 (JFMEOBDD_01955) - 2018544..2019095 (-) 552 WP_015898663.1 DNA-3-methyladenine glycosylase I -
  I2435_RS09700 (JFMEOBDD_01956) ruvA 2019105..2019701 (-) 597 WP_206156485.1 Holliday junction branch migration protein RuvA -

Sequence

Protein


Download         Length: 423 a.a.        Molecular weight: 45962.63 Da        Isoelectric Point: 5.0653

>NTDB_id=506513 I2435_RS09675 WP_043983216.1 2014153..2015424(-) (cinA) [Streptococcus equi subsp. zooepidemicus strain SEZ25]
MKAELIAVGTEILTGQIVNTNAQFLSEKMAELGIDVYFQTAVGDNEERLLSVIDIASQRSDLVILCGGLGPTDDDLTKQT
LAKYLGKALVFDEQAGQKLDAFFAHRKQTARTPNNQRQAQLIEGSVALQNQTGLAVGGLITVDGVTYVVLPGPPSELKPM
VKNELVPLLSASHASLYSRVLRFFGIGESQLVTALEDLIKYQTDPTIAPYAKTGEVTLRLSTKADHQALANERLDQLELQ
LLSIRTIDNQPLRRLLYGYGEDNSLARETFELLKRSGKTITAAESLTAGLFQAQLTDFAGASQVFNGGFITYSIEEKARM
LGIPLVELQRHGVVSSFTAEQMAAQARCLTDSDIGIGLTGVAGPEELEEQPAGTVFIGLATKNKVESLKVVIGGRSRLDV
RYIATLYAFNMVRKTLLKSENLL

Nucleotide


Download         Length: 1272 bp        

>NTDB_id=506513 I2435_RS09675 WP_043983216.1 2014153..2015424(-) (cinA) [Streptococcus equi subsp. zooepidemicus strain SEZ25]
ATGAAAGCTGAACTCATTGCGGTGGGAACCGAGATTCTGACTGGTCAGATTGTGAATACCAATGCTCAATTTTTATCAGA
AAAAATGGCGGAGCTTGGTATTGATGTTTATTTTCAAACAGCTGTAGGAGATAATGAAGAGCGTTTGCTTTCTGTTATTG
ATATTGCTAGCCAGCGAAGTGATTTAGTGATTTTATGTGGTGGTCTTGGTCCAACAGATGATGATCTAACGAAGCAGACC
TTAGCTAAGTATCTGGGAAAAGCTTTGGTCTTTGATGAGCAGGCAGGTCAAAAATTAGATGCTTTTTTTGCACATCGTAA
GCAGACTGCTAGGACACCAAACAACCAACGTCAGGCGCAGCTGATTGAAGGCTCTGTTGCTTTGCAAAATCAAACAGGAC
TTGCAGTAGGTGGCTTGATCACTGTAGATGGGGTAACCTATGTTGTCTTACCAGGGCCTCCAAGTGAGTTAAAGCCTATG
GTAAAAAATGAGCTGGTACCCCTTCTTTCAGCTAGTCACGCTAGTCTGTACTCAAGAGTGCTGCGCTTTTTTGGCATTGG
TGAGAGTCAACTGGTGACTGCTCTGGAGGATTTGATTAAGTATCAAACAGATCCTACTATTGCTCCTTATGCAAAGACCG
GCGAGGTAACACTGCGACTATCCACAAAGGCTGATCATCAAGCATTAGCTAATGAAAGGCTGGATCAGCTGGAGTTACAG
CTCTTATCCATAAGAACCATAGATAATCAACCCTTACGGCGTTTGCTTTATGGCTATGGGGAGGATAATTCCTTGGCACG
TGAGACCTTTGAGCTATTGAAGCGAAGTGGCAAGACGATAACAGCAGCTGAAAGCTTGACAGCAGGACTGTTTCAAGCCC
AGCTAACTGATTTTGCGGGAGCTTCACAGGTGTTTAACGGTGGCTTTATCACCTACAGCATTGAAGAAAAAGCAAGAATG
CTTGGTATTCCATTGGTTGAGCTCCAAAGGCATGGTGTTGTGAGCTCTTTTACAGCTGAGCAAATGGCTGCGCAGGCACG
TTGCTTGACCGATTCAGATATCGGTATTGGTCTAACAGGTGTTGCTGGTCCAGAGGAACTCGAGGAGCAGCCAGCAGGAA
CAGTTTTCATTGGCCTTGCCACTAAGAATAAGGTAGAATCTCTTAAAGTTGTCATAGGAGGTCGCAGCCGTTTGGACGTG
CGGTACATTGCTACTCTGTACGCTTTTAATATGGTTCGTAAAACTTTATTAAAATCAGAGAATTTGCTATAA

Domains

Predicted by InterproScan.

Damage-inducible protein CinA KH domain (CinA_KH)

(178-240)

Probable molybdopterin binding domain (MoCF_biosynth)

(5-169)

Competence-damaged protein (CinA)

(263-416)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cinA Streptococcus mutans UA159

70.922

100

0.709
  cinA Streptococcus mitis NCTC 12261

70.743

98.582

0.697
  cinA Streptococcus mitis SK321

70.743

98.582

0.697
  cinA Streptococcus pneumoniae TIGR4

70.264

98.582

0.693
  cinA Streptococcus pneumoniae Rx1

70.264

98.582

0.693
  cinA Streptococcus pneumoniae R6

70.264

98.582

0.693
  cinA Streptococcus pneumoniae D39

70.024

98.582

0.69
  cinA Streptococcus suis isolate S10

54.177

99.054

0.537
  cinA Bacillus subtilis subsp. subtilis str. 168

47.129

98.818

0.466