Detailed information NTG0506454

Bioinformatically predicted

Overview

• Name: cinA
• Type: Machinery gene
• Locus tag: I2434_RS09425
• Genome accession: NZ_CP065058
• Coordinates: 1990160..1991431 (-)
• Length: 423 a.a.
• NCBI ID: WP_043039523.1
• Uniprot ID: -
• Organism: Streptococcus equi subsp. zooepidemicus strain SEZ18
• Function: require for competence (predicted from homology) Unclear

Genomic Context

Location: 1985160..1996431

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
I2434_RS09400 (MCPGFBBE_01885)	-	1987048..1987347 (-)	300	WP_012516437.1	DUF1292 domain-containing protein	-
I2434_RS09405 (MCPGFBBE_01886)	ruvX	1987357..1987776 (-)	420	WP_015898660.1	Holliday junction resolvase RuvX	-
I2434_RS09410 (MCPGFBBE_01887)	-	1987773..1988042 (-)	270	WP_012516439.1	IreB family regulatory phosphoprotein	-
I2434_RS09415 (MCPGFBBE_01888)	spx	1988155..1988553 (-)	399	WP_012516440.1	transcriptional regulator Spx	-
I2434_RS09420 (MCPGFBBE_01889)	recA	1988930..1990066 (-)	1137	WP_012516441.1	recombinase RecA	Machinery gene
I2434_RS09425 (MCPGFBBE_01890)	cinA	1990160..1991431 (-)	1272	WP_043039523.1	competence/damage-inducible protein A	Machinery gene
I2434_RS09430 (MCPGFBBE_01891)	-	1992117..1992407 (-)	291	WP_043026774.1	hypothetical protein	-
I2434_RS09435 (MCPGFBBE_01892)	-	1992401..1992973 (-)	573	WP_165623160.1	phospholipase	-
I2434_RS09440 (MCPGFBBE_01893)	-	1993270..1994115 (+)	846	WP_115251407.1	helix-turn-helix transcriptional regulator	-
I2434_RS09445 (MCPGFBBE_01894)	-	1994559..1995110 (-)	552	WP_012678693.1	DNA-3-methyladenine glycosylase I	-
I2434_RS09450 (MCPGFBBE_01895)	ruvA	1995120..1995716 (-)	597	WP_012678694.1	Holliday junction branch migration protein RuvA	-

Sequence

Protein

• Length: 423 a.a.
• Molecular weight: 45971.64 Da
• Isoelectric Point: 5.1820

>NTDB_id=506454 I2434_RS09425 WP_043039523.1 1990160..1991431(-) (cinA) [Streptococcus equi subsp. zooepidemicus strain SEZ18]
MKAELIAVGTEILTGQIVNTNAQFLSEKMAELGIDVYFQTAVGDNEERLLSVIDIASQRSDLVILCGGLGPTDDDLTKQT
LAKYLGKALVFDEQAGQKLDAFFAHRKHTARTPNNQRQAQLIEGSVALQNQTGLAVGGLITVDGVTYVVLPGPPSELKPM
VKNELVPLLSASHASLYSRVLRFFGIGESQLVTALEDLIKYQTDPTIAPYAKTGEVTLRLSTKADHQALANERLDQLELQ
LLSIRTIDNQPLRRLLYGYGEDNSLARETFELLKRSGKTITAAESLTAGLFQAQLTDFAGASQVFNGGFITYSIEEKARM
LGIPLVELQRHGVVSSFTAEQMAAQARCLTDSDIGIGLTGVAGPEELEEQPAGTVFIGLATKNKVESLKVVIGGRSRLDV
RYIATLYAFNMVRKTLLKSENLL

Nucleotide

• Length: 1272 bp

>NTDB_id=506454 I2434_RS09425 WP_043039523.1 1990160..1991431(-) (cinA) [Streptococcus equi subsp. zooepidemicus strain SEZ18]
ATGAAAGCTGAACTCATTGCGGTGGGAACCGAGATTCTGACTGGTCAGATTGTGAATACCAATGCTCAATTTTTATCAGA
AAAAATGGCGGAGCTTGGTATTGATGTTTATTTTCAAACAGCTGTAGGAGATAATGAAGAGCGTTTGCTTTCTGTTATTG
ATATTGCTAGCCAGCGAAGTGATTTAGTGATTTTATGTGGTGGTCTTGGTCCAACAGATGATGATCTAACGAAGCAGACC
TTAGCTAAGTATCTGGGAAAAGCTTTGGTCTTTGATGAGCAGGCAGGTCAAAAATTAGATGCTTTTTTTGCACATCGTAA
GCATACTGCTAGGACACCAAACAACCAACGTCAGGCGCAGCTGATTGAAGGCTCTGTTGCTTTGCAAAATCAAACAGGAC
TTGCAGTAGGTGGCTTGATCACTGTAGATGGGGTAACCTATGTTGTCTTACCAGGGCCTCCAAGTGAGTTAAAGCCTATG
GTAAAAAATGAGCTGGTACCCCTTCTTTCAGCTAGTCACGCTAGTCTGTACTCAAGAGTGCTGCGCTTTTTTGGCATTGG
TGAGAGTCAACTGGTGACTGCTCTGGAGGATTTGATTAAGTATCAAACAGATCCTACTATTGCTCCTTATGCAAAGACCG
GCGAGGTAACACTGCGACTATCCACAAAGGCTGATCATCAAGCATTAGCTAATGAAAGGCTGGATCAGCTGGAGTTACAG
CTCTTATCCATAAGAACCATAGATAATCAACCCTTACGGCGTTTGCTTTATGGCTATGGGGAGGATAATTCCTTGGCACG
TGAGACCTTTGAGCTATTGAAGCGAAGTGGCAAGACGATAACAGCAGCTGAAAGCTTGACAGCAGGACTGTTTCAAGCCC
AGCTAACTGATTTTGCGGGAGCTTCACAGGTGTTTAACGGTGGCTTTATCACCTACAGCATTGAAGAAAAAGCAAGAATG
CTTGGTATTCCATTGGTTGAGCTCCAAAGGCATGGTGTTGTGAGCTCTTTTACAGCTGAGCAAATGGCTGCGCAGGCACG
TTGCTTGACCGATTCAGATATCGGTATTGGTCTAACAGGTGTTGCTGGTCCAGAGGAACTCGAGGAGCAGCCAGCAGGAA
CAGTTTTCATTGGCCTTGCCACTAAGAATAAGGTAGAATCTCTTAAAGTTGTCATAGGAGGTCGCAGCCGTTTGGACGTG
CGGTACATTGCTACTCTGTACGCTTTTAATATGGTTCGTAAAACTTTATTAAAATCAGAGAATTTGCTATAA

Domains

Predicted by InterproScan.

• Damage-inducible protein CinA KH domain (CinA_KH) (178-240)

• Probable molybdopterin binding domain (MoCF_biosynth) (5-169)

• Competence-damaged protein (CinA) (263-416)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
cinA	Streptococcus mutans UA159	70.922	100	0.709
cinA	Streptococcus mitis NCTC 12261	70.743	98.582	0.697
cinA	Streptococcus mitis SK321	70.743	98.582	0.697
cinA	Streptococcus pneumoniae TIGR4	70.264	98.582	0.693
cinA	Streptococcus pneumoniae Rx1	70.264	98.582	0.693
cinA	Streptococcus pneumoniae R6	70.264	98.582	0.693
cinA	Streptococcus pneumoniae D39	70.024	98.582	0.69
cinA	Streptococcus suis isolate S10	54.177	99.054	0.537
cinA	Bacillus subtilis subsp. subtilis str. 168	47.129	98.818	0.466